- First Course of treatment and Prognosis of Exocrine Pancreatic Cancer in Korea from 2006 to 2017
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Kang MJ, Lim J, Han SS, Park HM, Park SJ, Won YJ, Kim SW
- KMID: 2524601
- Cancer Res Treat.
- 2022 Jan;54(1):208-217.
- doi: 10.4143/crt.2021.421
Purpose Hospital-based clinical studies have limitations in holistic assessment of cancer treatment and prognosis, as they omit out-of-hospital patients including elderly individuals. This study aimed to investigate trends in initial treatment... -
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- Occupational Exposure to Pesticides and Lung Cancer Risk: A Propensity Score Analyses
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Kim B, Park EY, Kim J, Park E, Oh JK, Lim MK
- KMID: 2524594
- Cancer Res Treat.
- 2022 Jan;54(1):130-139.
- doi: 10.4143/crt.2020.1106
Purpose Occupational exposure to pesticides is thought to be associated with lung cancer, but studies have yielded conflicting results. We performed a propensity score (PS) based analyses to evaluate the... -
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- Validation of the Korean Version of the Patient-Reported Outcomes Measurement Information System 29 Profile V2.1 among Cancer Survivors
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Kang D, Kim Y, Lim J, Yoon J, Kim S, Kang E, Nam H, Shim S, Lee M, Bok H, Lee SW, Shin SY, Ahn JS, Oh D, Cho J
- KMID: 2524583
- Cancer Res Treat.
- 2022 Jan;54(1):10-19.
- doi: 10.4143/crt.2020.1200
Purpose The purpose of the study was to validate the Korean version of Patient-Reported Outcomes Measurement Information System 29 Profile v2.1 (K-PROMIS-29 V2.1) among cancer survivors. Materials and Methods Participants were... -
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- Association between the Persistence of Obesity and the Risk of Gastric Cancer: A Nationwide Population-Based Study
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Lim JH, Shin CM, Han KD, Lee SW, Jin EH, Choi YJ, Yoon H, Park YS, Kim N, Lee DH
- KMID: 2524600
- Cancer Res Treat.
- 2022 Jan;54(1):199-207.
- doi: 10.4143/crt.2021.130
Purpose There remains controversy about relationship between obesity and gastric cancer. We aimed to examine the association using obesity-persistence. Materials and Methods We analyzed a nationwide population-based cohort which underwent health... -
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- Oncological and Functional Outcomes of Larynx-preserving Surgery for Hypopharyngeal Cancer: A Comparison with Definitive Radiation-based Treatment
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Kim D, Kim N, Koh S, Chung MK, Son YI, Oh D, Jeong HS, Ahn YC
- KMID: 2524590
- Cancer Res Treat.
- 2022 Jan;54(1):84-95.
- doi: 10.4143/crt.2020.1197
Purpose Larynx-preserving surgery (LPS) have recently gained popularity and achieved comparable oncologic outcomes to conventional radical surgery for localized hypopharyngeal cancer (HPC). In the current study, the role of LPS... -
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- Recommendations for the Use of Next-Generation Sequencing and the Molecular Tumor Board for Patients with Advanced Cancer: A Report from KSMO and KCSG Precision Medicine Networking Group
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Yoon S, Kim M, Hong YS, Kim HS, Kim ST, Kim J, Yun H, Yoo C, Ahn HK, Kim HS, Lee IH, Kim IH, Park I, Jeong JH, Cheon J, Kim JW, Yun J, Lim SM, Cha Y, Jang SJ, Zang DY, Kim TW, Kang JH, Kim JH
- KMID: 2524582
- Cancer Res Treat.
- 2022 Jan;54(1):1-9.
- doi: 10.4143/crt.2021.1115
Next-generation sequencing (NGS) is becoming essential in the fields of precision oncology. With implementation of NGS in daily clinic, the needs for continued education, facilitated interpretation of NGS results and... -
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- Long-term Survival in Non–Small Cell Lung Cancer Patients with Metachronous Brain-Only Oligorecurrence Who Underwent Definitive Treatment
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Kim H, Park S, Jung HA, Sun JM, Lee SH, Ahn JS, Park K, Ahn MJ
- KMID: 2524596
- Cancer Res Treat.
- 2022 Jan;54(1):150-156.
- doi: 10.4143/crt.2021.306
Purpose Metachronous brain-only oligorecurrence in patients with non–small cell lung cancer (NSCLC) is a rare event with favorable prognosis, but the clinical outcome has not been fully determined. We retrospectively... -
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- Analysis of Cancer Patient Decision-Making and Health Service Utilization after Enforcement of the Life-Sustaining Treatment Decision-Making Act in Korea
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Kim D, Yoo SH, Seo S, Lee HJ, Kim MS, Shin SJ, Lim CY, Kim DY, Heo DS, Lim CM
- KMID: 2524584
- Cancer Res Treat.
- 2022 Jan;54(1):20-29.
- doi: 10.4143/crt.2021.131
Purpose This study aimed to confirm the decision-making patterns for life-sustaining treatment (LST) and analyze medical service utilization changes after enforcement of the Life-Sustaining Treatment Decision-Making Act. Materials and Methods Of... -
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- Absolute Neutrophil Count after the First Chemotherapy Cycle as a Surrogate Marker for Treatment Outcomes in Patients with Neuroblastoma
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Lee JW, Bae JS, Kim JH, Cho HW, Ju HY, Yoo KH, Koo HH, Woo Sy, Kim S, Sung KW
- KMID: 2524607
- Cancer Res Treat.
- 2022 Jan;54(1):259-268.
- doi: 10.4143/crt.2021.010
Purpose We performed this study to determine whether the degree of neutropenia after the first chemotherapy cycle can be used as a surrogate marker of individual susceptibility to chemotherapeutic agents... -
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- Effect of Waiting Time from Pathological Diagnosis to Definitive Concurrent Chemoradiation for Cervical Cancer on Overall Survival
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Noh KW, Kim B, Choi CH, Kim TJ, Lee JW, Kim BG, Bae DS, Cho WK, Park W, Lee YY
- KMID: 2524605
- Cancer Res Treat.
- 2022 Jan;54(1):245-252.
- doi: 10.4143/crt.2021.023
Purpose This study aimed to evaluate the effect of waiting time, from diagnosis to initiation of definitive concurrent chemoradiation (CCRT), on overall survival in cervical cancer patients. Materials and Methods Patients... -
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- Role of Roflumilast Combined with ESHAP Chemotherapy in Relapsed/Refractory Patients with Diffuse Large B-Cell Lymphoma
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Kim DY, Nam J, Chung Js, Kim SW, Shin HJ
- KMID: 2524611
- Cancer Res Treat.
- 2022 Jan;54(1):301-313.
- doi: 10.4143/crt.2020.1371
Purpose There are unmet needs associated with the current treatment strategies for relapsed/refractory diffuse large B-cell lymphoma (DLBCL) due to the poor treatment outcomes of these strategies. Roflumilast, a selective... -
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- Acquired Resistance Mechanism of EGFR Kinase Domain Duplication to EGFR TKIs in Non–Small Cell Lung Cancer
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Lee C, Kim M, Kim DW, Kim TM, Kim S, Im SW, Jeon YK, Keam B, Ku JL, Heo DS
- KMID: 2524595
- Cancer Res Treat.
- 2022 Jan;54(1):140-149.
- doi: 10.4143/crt.2021.385
Purpose Epidermal growth factor receptor kinase domain duplication (EGFR-KDD) is a rare and poorly understood oncogenic mutation in non–small cell lung cancer (NSCLC). We aimed to investigate the acquired resistance... -
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- Re-irradiation with Moderate Hypo-fractionation Using Intensity Modulated Photon or Proton Radiation Therapy in Locally Recurrent Squamous Cell Carcinoma of Nasopharynx
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Nam H, Ahn YC, Yang K, Oh D, Noh JM
- KMID: 2524591
- Cancer Res Treat.
- 2022 Jan;54(1):96-108.
- doi: 10.4143/crt.2020.1349
Purpose This study aimed to analyze the treatment outcomes of locally recurrent nasopharyngeal cancer (NPC) patients following moderate hypo-fractionation re-irradiation (re-RT). Materials and Methods Sixty locally recurrent NPC patients underwent hypo-fractionation... -
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- Increased Radiosensitivity of Solid Tumors Harboring ATM and BRCA1/2 Mutations
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Kim KH, Kim HS, Kim Ss, Shim HS, Yang AJ, Lee JJB, Yoon HI, Ahn JB, Chang JS
- KMID: 2524587
- Cancer Res Treat.
- 2022 Jan;54(1):54-64.
- doi: 10.4143/crt.2020.1247
Purpose Preclinical data indicate that response to radiotherapy (RT) depends on DNA damage repair. In this study, we investigated the role of mutations in genes related to DNA damage repair in... -
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- Potentiation of the Anticancer Effects by Combining Docetaxel with Ku-0063794 against Triple-Negative Breast Cancer Cells
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Jeon YW, Kim OH, Shin JS, Hong HE, Kim CH, Kim SJ
- KMID: 2524597
- Cancer Res Treat.
- 2022 Jan;54(1):157-173.
- doi: 10.4143/crt.2020.1063
Purpose mTORC1 and mTORC2 inhibition by Ku-0063794 could confer profound anticancer effects against cancer cells because it eliminates feedback activation of Akt. Herein, we aimed to determine anticancer effects of... -
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- Vps34 Inhibits Hepatocellular Carcinoma Invasion by Regulating Endosome-Lysosome Trafficking via Rab7-RILP and Rab11
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Qi C, Zou L, Wang S, Mao X, Hu Y, Shi J, Zhang Z, Wu H
- KMID: 2524599
- Cancer Res Treat.
- 2022 Jan;54(1):182-198.
- doi: 10.4143/crt.2020.578
Purpose The role of vacuolar protein sorting 34 (Vps34), an indispensable protein required for cell vesicular trafficking, in the biological behavior of hepatocellular carcinoma (HCC) has yet to be studied. Materials... -
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- Evaluation of a Direct Reverse Transcription Loop-Mediated Isothermal Amplification Method without RNA Extraction (Direct RT-LAMP) for the Detection of Lymph Node Metastasis in Early Breast Cancer
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Lee IH, Jung JH, Lee SJ, Lee J, Park HY, Park JY, Park JY, Jung Jh, Lee H, Jeon HS, Chae YS
- KMID: 2524598
- Cancer Res Treat.
- 2022 Jan;54(1):174-181.
- doi: 10.4143/crt.2020.749
Purpose Assessing lymph node metastasis, tumor-derived DNA, or tumor-derived RNA has previously been studied in place of immunohistochemical assay. Because a direct reverse transcription loop-mediated isothermal amplification method (direct RT-LAMP)... -
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- Targeted Liquid Biopsy Using Irradiation to Facilitate the Release of Cell-Free DNA from a Spatially Aimed Tumor Tissue
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Noh JM, Kim YJ, Lee HY, Choi C, Ahn WG, Lee T, Pyo H, Park JH, Park D, Park WY
- KMID: 2524586
- Cancer Res Treat.
- 2022 Jan;54(1):40-53.
- doi: 10.4143/crt.2021.151
Purpose We investigated the feasibility of using an anatomically localized, target-enriched liquid biopsy (TLB) in mouse models of lung cancer. Materials and Methods After irradiating xenograft mouse with human lung cancer... -
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- Long-term Survivals, Toxicities and the Role of Chemotherapy in Early-Stage Nasopharyngeal Carcinoma Patients Treated with Intensity-Modulated Radiation Therapy: A Retrospective Study with 15-Year Follow-up
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Wang L, Miao J, Huang H, Chen B, Xiao X, Zhu M, Liang Y, Xiao W, Huang S, Peng Y, Deng X, Lv X, Xia W, Xiang Y, Guo X, Han F, Zhao C
- KMID: 2524593
- Cancer Res Treat.
- 2022 Jan;54(1):118-129.
- doi: 10.4143/crt.2021.101
Purpose This study was aimed to investigate long-term survivals and toxicities of early-stage nasopharyngeal carcinoma (NPC) in endemic area, evaluating the role of chemotherapy in stage II patients. Materials and Methods... -
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- The Prognosis and the Role of Adjuvant Chemotherapy for Node-Positive Bladder Cancer Treated with Neoadjuvant Chemotherapy Followed by Surgery
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Jeong H, Park KJ, Lee Y, Kim HD, Kim JH, Yoon S, Hong B, Lee JL
- KMID: 2524603
- Cancer Res Treat.
- 2022 Jan;54(1):226-233.
- doi: 10.4143/crt.2021.365
Purpose This study aims to evaluate the prognosis of pathologically node-positive bladder cancer after neoadjuvant chemotherapy, the role of adjuvant chemotherapy in these patients, and the value of preoperative clinical... -
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