- Hematopoietic Stem Cells and Their Roles in Tissue Regeneration
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Lee JY, Hong SH
- KMID: 2500562
- Int J Stem Cells.
- 2020 Mar;13(1):1-12.
- doi: 10.15283/ijsc19127
Hematopoietic stem cells (HSCs) are regarded as one of essential cell sources for treating regenerative diseases. Among many stem cells, the feasibility of using adult-derived hematopoietic stem cells in therapeutic... -
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- Manipulated Mesenchymal Stem Cells Applications in Neurodegenerative Diseases
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Sadatpoor , Salehi Z, Rahban D, Salimi A
- KMID: 2500564
- Int J Stem Cells.
- 2020 Mar;13(1):24-45.
- doi: 10.15283/ijsc19031
Mesenchymal stem cells (MSCs) are multipotent stem cells that have multilinear differentiation and self-renewal abilities. These cells are immune-privileged as they express no or low level of class-II major histocompatibility... -
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- Mesenchymal Stem Cell-Derived Exosomes: A Promising Therapeutic Ace Card to Address Autoimmune Diseases
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Baharlooi , Azimi M, Salehi Z, Izad M
- KMID: 2500563
- Int J Stem Cells.
- 2020 Mar;13(1):13-23.
- doi: 10.15283/ijsc19108
With the development of novel treatments for autoimmune disorders, it has become a popular research focus which mesenchymal stem cells (MSCs) have the capacity to counteract with autoimmune diseases progression.... -
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- Quantitative Tracking Tumor Suppression Efficiency of Human Umbilical Cord-Derived Mesenchymal Stem Cells by Bioluminescence Imaging in Mice Hepatoma Model
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Liu J, Shi Y, Han J, Zhang Y, Cao Z, Cheng J
- KMID: 2500570
- Int J Stem Cells.
- 2020 Mar;13(1):104-115.
- doi: 10.15283/ijsc19098
Background and Objectives: Tracking of the tumor progression by MSCs-based therapy is being increasingly important in evaluating relative therapy effectively. Herein, Bioluminescence imaging (BLI) technology was used to dynamically and... -
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- Hyaluronan Induces a Mitochondrial Functional Switch in Fast-Proliferating Human Mesenchymal Stem Cells
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Solis MA, Wei YH, Chang CH, Yu CH, Huang LL
- KMID: 2500574
- Int J Stem Cells.
- 2020 Mar;13(1):151-162.
- doi: 10.15283/ijsc19004
Background and Objectives: Hyaluronan preserves the proliferation and differentiation potential of mesenchymal stem cells. Supplementation of low-concentration hyaluronan (SHA) in stem cells culture medium increases its proliferative rate, whereas coated-surface... -
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- The Overexpression of Epidermal Growth Factor (EGF) in HaCaT Cells Promotes the Proliferation, Migration, Invasion and Transdifferentiation to Epidermal Stem Cell Immunophenotyping of Adipose-Derived Stem Cells (ADSCs)
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Mao Y, Ma J, Xia Y, Xie X
- KMID: 2500569
- Int J Stem Cells.
- 2020 Mar;13(1):93-103.
- doi: 10.15283/ijsc18146
Background and Objectives: The application of adipose derived stem cells (ADSCs) in skin repair has attracted much attention nowadays. Epidermal growth factor (EGF) participates in the progress of skin proliferation,... -
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- Molecular Characterization of Embryonic Stem Cell-Derived Cardiac Neural Crest-Like Cells Revealed a Spatiotemporal Expression of an Mlc-3 Isoform
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Schmitteckert S, Ziegler C, Rappold GA, Niesler B, Rolletschek A
- KMID: 2500567
- Int J Stem Cells.
- 2020 Mar;13(1):65-79.
- doi: 10.15283/ijsc19069
Background and Objectives: Pluripotent embryonic stem (ES) cells represent a perfect model system for the investigation of early developmental processes. Besides their differentiation into derivatives of the three primary germ... -
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- Estrogen Promotes cAMP Production in Mesenchymal Stem Cells by Regulating ADCY2
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Zhao G, Li X, Miao H, Chen S, Hou Y
- KMID: 2500566
- Int J Stem Cells.
- 2020 Mar;13(1):55-64.
- doi: 10.15283/ijsc19139
Background and Objectives: The maternal-fetal interface is an important source of mesenchymal stem cells (MSCs), and it is influenced by high levels of estradiol (E2) during pregnancy. It is highly... -
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- Neurogenin-1 Overexpression Increases the Therapeutic Effects of Mesenchymal Stem Cells through Enhanced Engraftment in an Ischemic Rat Brain
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Kim GH, Subash M, Yoon JS, Jo D, Han J, Hong JM, Kim SS, Kim HS
- KMID: 2500572
- Int J Stem Cells.
- 2020 Mar;13(1):127-141.
- doi: 10.15283/ijsc19111
Background and Objectives: Stem cell therapy is a promising strategy for treating neurological diseases but its effectiveness is influenced by the route of administration and the characteristics of the stem... -
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- IL6 Receptor Facilitates Adipogenesis Differentiation of Human Mesenchymal Stem Cells through Activating P38 Pathway
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Deng W, Chen H, Su H, Wu X, Xie Z, Wu Y, Shen H
- KMID: 2500573
- Int J Stem Cells.
- 2020 Mar;13(1):142-150.
- doi: 10.15283/ijsc19073
Background and Objectives: Mesenchymal stem cells (MSCs) have the multipotent capacity to differentiate into multiple tissue lineages as well as to self-renew, which is the main origin of adipocytes. IL6/IL6R... -
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- Robust and Reproducible Generation of Induced Neural Stem Cells from Human Somatic Cells by Defined Factors
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Kwak TH, Hali S, Kim S, Kim J, La H, Kim KP, Hong KH, Shin CY, Kim NH, Han DW
- KMID: 2500568
- Int J Stem Cells.
- 2020 Mar;13(1):80-92.
- doi: 10.15283/ijsc19097
Background and Objectives: Recent studies have described direct reprogramming of mouse and human somatic cells into induced neural stem cells (iNSCs) using various combinations of transcription factors. Although iNSC technology... -
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- Protective Effect of Human Mesenchymal Stem Cells on the Survival of Pancreatic Islets
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Fumagalli , Monfrini M, Donzelli E, Rodriguez-Menendez V, Bonandrini B, Figliuzzi , Remuzzi A, D’Amico G, Cavaletti , Scuteri A
- KMID: 2500571
- Int J Stem Cells.
- 2020 Mar;13(1):116-126.
- doi: 10.15283/ijsc19094
Background and Objectives: Transplantation of pancreatic islets is an intriguing new therapeutic option to face the worldwide spread problem of Type-I diabetes. Currently, its clinical use is limited by several... -
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- miR-450a-5p Eliminates MGO-Induced Insulin Resistance via Targeting CREB
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Wei C, Meng L, Zhang Y
- KMID: 2500565
- Int J Stem Cells.
- 2020 Mar;13(1):46-54.
- doi: 10.15283/ijsc19088
Background and Objectives: miR-450a-5p was involved in fat formation, however, its role in insulin resistance remains unclear. This study investigated the effects of miR-450a-5p on endothelial cells, with the aim... -
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- Effect of Stem Cells, Ascorbic Acid and SERCA1a Gene Transfected Stem Cells in Experimentally Induced Type I Diabetic Myopathy
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Zickri MB, Sadek EM, Fares AE, Heteba NG, Reda AM
- KMID: 2500575
- Int J Stem Cells.
- 2020 Mar;13(1):163-175.
- doi: 10.15283/ijsc18066
Background and Objectives: Sarco/endoplasmic reticulum Ca2＋-ATPase (SERCA) inhibition was proved in streptozotocin (STZ)-diabetic rats. The present study aimed at investigating and comparing the therapeutic effect of bone marrow mesenchymal stem... -
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