- Comparison of Invariant NKT Cells with Conventional T Cells by Using Gene Set Enrichment Analysis (GSEA)
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Oh SJ, Ahn JY, Chung DH
- KMID: 2150727
- Immune Netw.
- 2011 Dec;11(6):406-411.
- doi: 10.4110/in.2011.11.6.406
BACKGROUND: Invariant Natural killer T (iNKT) cells, a distinct subset of CD1d-restricted T cells with invariant Valphabeta TCR, functionally bridge innate and adaptive immunity. While iNKT cells share features with... -
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- Immunomodulatory Effects of Hypocrellin A on MHC-restricted Antigen Processing
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Park S, Im SA, Kim KH, Lee CK
- KMID: 2150728
- Immune Netw.
- 2011 Dec;11(6):412-415.
- doi: 10.4110/in.2011.11.6.412
Hypocrellin A has gained much attention in recent years due to its light-induced antitumor, antifungal and antiviral activities. Here we report that hypocrellin A exerts immunomodulatory effects on MHC-restricted presentation... -
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- HLA and Disease Associations in Koreans
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Ahn S, Choi HB, Kim TG
- KMID: 2150716
- Immune Netw.
- 2011 Dec;11(6):324-335.
- doi: 10.4110/in.2011.11.6.324
The human leukocyte antigen (HLA), the major histocompatibility complex (MHC) in humans has been known to reside on chromosome 6 and encodes cell-surface antigen-presenting proteins and many other proteins related... -
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- Influence of Interferon-gamma Deficiency in Immune Tolerance Induced by Male Islet Transplantation
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Kim YH, Lim Y, Park CG
- KMID: 2150720
- Immune Netw.
- 2011 Dec;11(6):358-363.
- doi: 10.4110/in.2011.11.6.358
BACKGROUND: Traditionally, interferon-gamma (IFN-gamma) was regarded as a pro-inflammatory cytokine, however, recent reports suggested role of IFN-gamma in immune tolerance. In our previous report, we could induce tolerance to male... -
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- Production of Prostaglandin E2 and I2 Is Coupled with Cyclooxygenase-2 in Human Follicular Dendritic Cells
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Cho W, Kim J, Cho KB, Choe J
- KMID: 2150721
- Immune Netw.
- 2011 Dec;11(6):364-367.
- doi: 10.4110/in.2011.11.6.364
BACKGROUND: Prostaglandins (PGs) play pathogenic and protective roles in inflammatory diseases. The novel concept of PGs as immune modulators is being documented by several investigators. By establishing an in vitro... -
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- NDRG2 Promotes GATA-1 Expression through Regulation of the JAK2/STAT Pathway in PMA-stimulated U937 Cells
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Kang K, Jung H, Nam S, Lim JS
- KMID: 2150719
- Immune Netw.
- 2011 Dec;11(6):348-357.
- doi: 10.4110/in.2011.11.6.348
BACKGROUND: N-myc downstream-regulated gene 2 (NDRG2), a member of a newly described family of differentiation-related genes, has been characterized as a regulator of dendritic cells. However, the role of NDRG2... -
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- Anti-CD137 mAb Deletes Both Donor CD4+ and CD8+ T Cells in Acute Graft-versus-host Disease
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Kim J, Cho HR, Kwon B
- KMID: 2150732
- Immune Netw.
- 2011 Dec;11(6):428-430.
- doi: 10.4110/in.2011.11.6.428
We previously demonstrated that in vivo engagement of CD137, a member of TNF receptor superfamily, can delete allorective CD4+ T cells through the induction of activation-induced cell death (AICD) in... -
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- CKD-712, (S)-1-(alpha-naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, Inhibits the NF-kappaB Activation and Augments Akt Activation during TLR4 Signaling
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Lee J, Yang EJ, Shin JS, Kim DH, Lee SS, Choi IH
- KMID: 2150730
- Immune Netw.
- 2011 Dec;11(6):420-423.
- doi: 10.4110/in.2011.11.6.420
Since CKD-712 has been developed as an anti-inflammatory agent, we examined the effect of CKD-712 during TLR4 signaling. Using HEK293 cells expressing TLR4, CKD-712 was pre-treated 1 hr before LPS... -
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- Maturation-Resistant Dendritic Cells Ameliorate Experimental Autoimmune Uveoretinitis
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Oh K, Kim YS, Lee DS
- KMID: 2150726
- Immune Netw.
- 2011 Dec;11(6):399-405.
- doi: 10.4110/in.2011.11.6.399
BACKGROUND: Endogenous uveitis is a chronic inflammatory eye disease of human, which frequently leads to blindness. Experimental autoimmune uveoretinitis (EAU) is an animal disease model of human endogenous uveitis and... -
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- Modulation of Glial and Neuronal Migration by Lipocalin-2 in Zebrafish
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Kim H, Lee S, Park HC, Lee WH, Lee MS, Suk K
- KMID: 2150718
- Immune Netw.
- 2011 Dec;11(6):342-347.
- doi: 10.4110/in.2011.11.6.342
BACKGROUND: Glial cells are involved in immune and inflammatory responses in the central nervous system (CNS). Glial cells such as microglia and astrocytes also provide structural and functional support for... -
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- MicroRNAs in Human Diseases: From Lung, Liver and Kidney Diseases to Infectious Disease, Sickle Cell Disease and Endometrium Disease
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Ha TY
- KMID: 2150715
- Immune Netw.
- 2011 Dec;11(6):309-323.
- doi: 10.4110/in.2011.11.6.309
MicroRNAs (miRNAs) are a class of naturally occurring small non-coding RNAs of about 22 nucleotides that have recently emerged as important regulators of gene expression at the posttranscriptional level. Recent... -
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- The Role of Intracellular Receptor NODs for Cytokine Production by Macrophages Infected with Mycobacterium leprae
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Kang TJ, Chae GT
- KMID: 2150731
- Immune Netw.
- 2011 Dec;11(6):424-427.
- doi: 10.4110/in.2011.11.6.424
The nucleotide-oligomerization domain (NOD) proteins are members of the NOD-like receptor (NLR) family, which are intracellular and cytoplasmic receptors. We analyzed the role of NODs for cytokine production by macrophages... -
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- T Cell Receptor Signaling That Regulates the Development of Intrathymic Natural Regulatory T Cells
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Song KD, Hwang S, Yun CH
- KMID: 2150717
- Immune Netw.
- 2011 Dec;11(6):336-341.
- doi: 10.4110/in.2011.11.6.336
T cell receptor (TCR) signaling plays a critical role in T cell development, survival and differentiation. In the thymus, quantitative and/or qualitative differences in TCR signaling determine the fate of... -
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- Th17 Responses Are Not Induced in Dextran Sodium Sulfate Model of Acute Colitis
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Kim YS, Lee MH, Ju AS, Rhee KJ
- KMID: 2150729
- Immune Netw.
- 2011 Dec;11(6):416-419.
- doi: 10.4110/in.2011.11.6.416
Dextran sodium sulfate (DSS) is a widely used chemical model for inflammatory bowel disease (IBD). It is thought that imbalances in the T helper (Th) cell subsets contribute to IBD.... -
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- Cellular Mechanism of Newly Synthesized Indoledione Derivative-induced Immunological Death of Tumor Cell
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Oh SJ, Ryu CK, Baek SY, Lee H
- KMID: 2150724
- Immune Netw.
- 2011 Dec;11(6):383-389.
- doi: 10.4110/in.2011.11.6.383
BACKGROUND: EY-6 is one of the newly synthesized indoledione derivatives to induce tumor cell-specific cell death. In this study, we investigated the mechanism of immunological death induced by EY-6 at... -
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- Cross-linking of CD80 and CD86 Diminishes Expression of CD54 on EBV-transformed B Cells through Inactivation of RhoA and Ras
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Park GB, Kim YS, Song H, Kim S, Park DM, Lee WJ, Hur DY
- KMID: 2150725
- Immune Netw.
- 2011 Dec;11(6):390-398.
- doi: 10.4110/in.2011.11.6.390
BACKGROUND: Epstein Barr virus (EBV) infected B cells are transformed into lymphoblastoid cell lines. Some researchers suggested some a few similarities between this process and carcinogenesis. We observed the expression... -
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- CO/HO-1 Induces NQO-1 Expression via Nrf2 Activation
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Kim HJ, Zheng M, Kim SK, Cho JJ, Shin CH, Joe Y, Chung HT
- KMID: 2150723
- Immune Netw.
- 2011 Dec;11(6):376-382.
- doi: 10.4110/in.2011.11.6.376
BACKGROUND: Carbon monoxide (CO) is a cytoprotective and homeostatic molecule with important signaling capabilities in physiological and pathophysiological situations. CO protects cells/tissues from damage by free radicals or oxidative stress.... -
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- Blockade of Vascular Endothelial Growth Factor (VEGF) Aggravates the Severity of Acute Graft-versus-host Disease (GVHD) after Experimental Allogeneic Hematopoietic Stem Cell Transplantation (allo-HSCT)
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Kim AR, Lim JY, Jeong DC, Park G, Lee BC, Min CK
- KMID: 2150722
- Immune Netw.
- 2011 Dec;11(6):368-375.
- doi: 10.4110/in.2011.11.6.368
BACKGROUND: Recent clinical observation reported that there was a significant correlation between change in circulating vascular endothelial growth factor (VEGF) levels and the occurrence of severe acute graft-versus-host disease (GVHD)... -
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