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Genetic variations in open reading frame 2 gene of porcine circovirus type 2 isolated in Korea during 2016–2017

Kim K, Choi JY, Lyoo KS, Hahn TW

The capsid protein of porcine circovirus type 2 (PCV2) encoded by open reading frame 2 (ORF2) is important for neutralizing activity against PCV2 infection. This study investigated the heterogeneity of...
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Detection and genetic characterization of porcine circovirus 3 from aborted fetuses and pigs with respiratory disease in Korea

Kim SH, Park JY, Jung JY, Kim HY, Park YR, Lee KK, Lyoo YS, Yeo SG, Park CK

A novel porcine circovirus 3 (PCV3) was first detected in pigs showing porcine dermatitis and nephropathy syndrome, reproductive failure, and multisystemic inflammation in the USA. Herein, we report on PCV3...
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Pathologic studies in lymph nodes of pigs infected with porcine circovirus type 2, porcine reproductive and respiratory syndrome virus

Jung JY, Kim JH

  • KMID: 1790572
  • Korean J Vet Res.
  • 2013 Dec;53(4):245-251.
Porcine circovirus type 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) have been suspected to have immunosuppressive effects on pigs. To investigate the correlation between these virus infection...
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Recent vaccine technology in industrial animals

Kim H, Lee YK, Kang SC, Han BK, Choi KM

Various new technologies have been applied for developing vaccines against various animal diseases. Virus-like particle (VLP) vaccine technology was used for manufacturing the porcine circovirus type 2 and RNA particle...
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Prevalence of porcine reproductive and respiratory syndrome virus, porcine circovirus type 2 and porcine parvovirus from aborted fetuses and pigs with respiratory problems in Korea

Lyoo KS, Park YH, Park BK

  • KMID: 1119216
  • J Vet Sci.
  • 2001 Dec;2(3):201-207.
Porcine reproductive and respiratory syndrome virus(PRRSV)0, porcine circovirus type 2(PCV-2) and porcine parvovirus (PPV)0 infections were investigated as possible causes of the postweaning multisystemic wasting syndrome(PMWS). Specific primers for RT-PCR...
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Porcine circovirus type 2 increases interleukin-1beta and interleukin-10 production via the MyD88–NF-kappa B signaling pathway in porcine alveolar macrophages in vitro

Han J, Zhang S, Zhang Y, Chen M, Lv Y

Porcine alveolar macrophages (PAMs) represent the first line of defense in the porcine lung after infection with porcine circovirus type 2 (PCV2) via the respiratory tract. However, PCV2 infection impairs...
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Age-specific Prevalence of Porcine Reproductive and Respiratory Syndrome Virus, Porcine Circovirus Type 2, and Mycoplasma hyopneumoniae in Korea Pig Farms

Kang I, Ham H

Porcine respiratory disease complex (PRDC) continues to be a significant economic problem to the swine industry. Porcine circovirus type 2 (PCV2), porcine reproductive and respiratory syndrome virus (PRRSV), and Mycoplasma...
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Duplex nested reverse transcriptase polymerase chain reaction for simultaneous detection of type 2 porcine reproductive and respiratory syndrome virus and porcine circovirus type 2 from tissue samples

Kim HK, Lyoo KS, Huynh TM, Moon HJ, Nguyen VG, Park BK

There are high levels of co-incidence of porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus type 2 (PCV2) in porcine tissue. This study established a duplex nested reverse...
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Genetic characterization of porcine circovirus-2 field isolates from PMWS pigs

Kim JH, Lyoo YS

  • KMID: 1101572
  • J Vet Sci.
  • 2002 Mar;3(1):31-39.
PMWS is a new emerging disease in swine herds worldwide. Field isolates of PCV-2, a putative major causative agent of PMWS, were isolated and genetically characterized. Viral genome of two...
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Assessing PCV2 antibodies in field pigs vaccinated with different porcine circovirus 2 vaccines using two commercial ELISA systems

Shin MK, Yoon SH, Kim MH, Lyoo YS, Suh SW, Yoo HS

Porcine circovirus type 2 (PCV2) is the primary causative agent for post-weaning, multisystemic, wasting syndrome. Consequently, serologic detection of and vaccination against PCV2 are important for the swine industry. Among...
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Characterization of the Recombinant Proteins of Porcine Circovirus Type2 Field Isolate Expressed in the Baculovirus System

Kim Y, Kim J, Kang K, Lyoo YS

  • KMID: 1101570
  • J Vet Sci.
  • 2002 Mar;3(1):19-23.
Porcine circovirus (PCV) type2 was isolated using primary porcine kidney cells from lymph node of piglets with typical PMWS. The presence of the virus was identified by PCR using primers...
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Genetic Characterization of Porcine Circovirus Type 2 Detected from the Pigs in Commercial Swine Farms in Korea

Oh SS, Chu J, Park SH, Park CS, Kim MC, Jun MH

Porcine circovirus type 2 (PCV-2) has been nowadays recognized as a major agent causing postweaning multisystemic wasting syndrome (PMWS) in pigs worldwide. PMWS most commonly affects the weaned piglets, being...
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Enhancing mucosal immunity in mice by recombinant adenovirus expressing major epitopes of porcine circovirus-2 capsid protein delivered with cytosine-phosphate-guanosine oligodeoxynucleotides

Chang HT, He XY, Liu YF, Chen L, Guo QH, Yu QY, Zhao J, Wang XW, Yang X, Wang CQ

A recombinant replication-defective adenovirus expressing the major epitopes of porcine circovirus-2 (PCV-2) capsid protein (rAd/Cap/518) was previously constructed and shown to induce mucosal immunity in mice following intranasal delivery. In...
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Enhanced protective immune response to PCV2 adenovirus vaccine by fusion expression of Cap protein with InvC in pigs

Zhang Z, Luo Y, Zhang Y, Guo K

The major immunogenic protein capsid (Cap) of porcine circovirus type 2 (PCV2) is critical to induce neutralizing antibodies and protective immune response against PCV2 infection. This study was conducted to...
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Nucleotide Sequencing and Expression of Type 2 Porcine Circoviruses Isolated in Korea

Kim KM, Park HS, Kim JH, Kang SY

  • KMID: 1515657
  • J Bacteriol Virol.
  • 2003 Jun;33(2):151-160.
Porcine circovirus (PCV) is a small, nonenveloped virus that contains a single-stranded circular DNA genome of about 1.76 Kb and belongs to the family Circoviridae. The PCV-2 was thought to...
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Distribution and characterization of IL-10-secreting cells in lymphoid tissues of PCV2-infected pigs

Doster AR, Subramaniam S, Yhee JY, Kwon BJ, Yu CH, Kwon SY, Osorio FA, Sur JH

Distribution and characterization of interlukin-10 (IL-10)-secreting cells in lymphoid tissues of pigs naturally infected with porcine circovirus type 2 (PCV2) were evaluated in accordance with PCV2 antigen detection. After screening...
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Quantification and genotyping of PCV2 DNA in the tissues of PCV2-infected conventional pigs with different clinical signs

Kim HK, Luo Y, Moon HJ, Park SJ, Rho SM, Han JY, Nguyen VG, Park BK

  • KMID: 1991809
  • Korean J Vet Res.
  • 2011 Mar;51(1):7-14.
This study was focused on the genotyping and quantification of Porcine circovirus type 2 (PCV2) in thirty PCV2-positive pigs with different clinical symptoms (PCV2-infected without wasting, PCV2-infected with wasting, PCV2-infected...
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Prevalence and pathologic study of porcine salmonellosis in Jeju

Yang HS, Kang SC, Kim AR, Jung BY, Kim JH

Salmonella (S.) Typhimurium is highly contagious, and its infection may rapidly spread within pig populations of herd. According to the survey (1,191 pigs) from 2003 to 2012, 155 pigs (13.0%)...
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Prevalence of porcine parvovirus in pigs with postweaning multisystemic wasting syndrome in Jeju Island

Ko KN, Jung JY, Kang SC, Kim KS, Kim JH, Kim DY, Hwang EK, Kim JH

  • KMID: 1991800
  • Korean J Vet Res.
  • 2011 Sep;51(3):203-208.
Postweaning multisystemic wasting syndrome (PMWS), which was first identified in western Canada in 1991 and more recently in the United States, Europe and Asia, is an emerging disease in pigs....
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Epidemiological characteristics of pulmonary pneumocystosis and concurrent infections in pigs in Jeju Island, Korea

Kim KS, Jung JY, Kim JH, Kang SC, Hwang EK, Park BK, Kim DY, Kim JH

Epidemiological characteristics of swine pulmonary Pneumocystis (P.) carinii and concurrent infections were surveyed on Jeju Island, Korea, within a designated period in 172 pigs submitted from 54 farms to the...
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