Korean J Vet Res.  2011 Sep;51(3):203-208.

Prevalence of porcine parvovirus in pigs with postweaning multisystemic wasting syndrome in Jeju Island

• Ko KN
• Jung JY
• Kang SC
• Kim KS
• Kim JH
• Kim DY
• Hwang EK
• Kim JH

Abstract

Postweaning multisystemic wasting syndrome (PMWS), which was first identified in western Canada in 1991 and more recently in the United States, Europe and Asia, is an emerging disease in pigs. Porcine circovirus type 2 (PCV-2) is the primary infectious viral agent causing PMWS, but the full expression of the disease may require the presence of other agents. It is reported that there is apparent synergism between PCV-2 and porcine parvovirus (PPV) in increasing the severity of the clinical signs and lesions of PMWS. From January 2006 to May 2008, a total of the 154 lymph node samples were collected from 4~12 weeks old pigs which had been submitted to the College of Veterinary Medicine, Jeju National University, Korea. These pigs were diagnosed as PMWS on the basis of clinical and pathological examination from 48 commercial herds in Jeju Island. Based on the immunohistochemistry, porcine parvovirus was detected in 69 cases (44.8%) from 154 weaned or grower pigs. PPV antigens were detected in the cytoplasm of histiocytic cells multifocally infiltrated in the cortex and paracortex of lymph nodes. The results of this study clarify that PPV is prevalent in pigs with PMWS on Jeju Island. Therefore PPV is one of the most important co-agents in the development of naturally acquired PMWS. This study may be helpful to the control of this disease and to epidemiological aspects.

Keyword

co-infection; immunohistochemistry; Jeju Island; PMWS; porcine parvovirus

MeSH Terms

Asia
Canada
Circovirus
Coinfection
Cytoplasm
Europe
Immunohistochemistry
Korea
Lymph Nodes
Parvovirus, Porcine
Prevalence
Swine
United States
Veterinary Medicine
Wasting Syndrome