Korean J Vet Res.
2018 Sep;58(3):143-146. 10.14405/kjvr.2018.58.3.143.
Genetic variations in open reading frame 2 gene of porcine circovirus type 2 isolated in Korea during 2016–2017
- Affiliations
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- 1College of Veterinary Medicine & Institute of Veterinary Science, Kangwon National University, Chuncheon 24341, Korea. twhahn@kangwon.ac.kr
- 2Dodam Veterinary Clinic, Seoul 04716, Korea.
- 3Korea Zoonosis Research Institute, Chonbuk National University, Iksan 54531, Korea.
- KMID: 2437685
- DOI: http://doi.org/10.14405/kjvr.2018.58.3.143
Abstract
- The capsid protein of porcine circovirus type 2 (PCV2) encoded by open reading frame 2 (ORF2) is important for neutralizing activity against PCV2 infection. This study investigated the heterogeneity of the ORF2 gene of PCV2 isolated in Korea during 2016-2017. The results revealed that PCV2d is currently the predominant genotype. Moreover, comparison of ORF2 from 17 PCV2 isolates revealed 88.3-100% homology at the nucleotide (deduced amino acid 86.3-100%) level. Interestingly, 61.5% (8/13) of the PCV2d isolates had glycine at position 210. These data provide a useful information for PCV2 epidemiology in Korea.
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