- Impact of Social Support during Diagnosis and Treatment on Disease Progression in Young Patients with Breast Cancer: A Prospective Cohort Study
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Kang D, Park S, Kim HJ, Kim SW, Lee JE, Yu J, Lee SK, Kim JY, Nam SJ, Cho J, Park YH
- KMID: 2550329
- Cancer Res Treat.
- 2024 Jan;56(1):125-133.
- doi: 10.4143/crt.2023.673
Purpose We evaluated the association between changes in social support after cancer treatment and recurrence-free survival (RFS) in such patients using a prospective cohort study. Materials and Methods Data were obtained... -
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- Clinical Features of Li-Fraumeni Syndrome in Korea
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Song R, Kong SY, Choi W, Lee EG, Woo J, Han JH, Lee S, Kang HS, Jung SY
- KMID: 2550348
- Cancer Res Treat.
- 2024 Jan;56(1):334-341.
- doi: 10.4143/crt.2023.794
Purpose Li-Fraumeni syndrome (LFS) is a hereditary disorder caused by germline mutation in TP53. Owing to the rarity of LFS, data on its clinical features are limited. This study aimed... -
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- Intensity-Modulated Radiation Therapy for Uterine Cervical Cancer to Reduce Toxicity and Enhance Efficacy – an Option or a Must?: A Narrative Review
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Lee SW, Kim A, Lee SJ, Kim SH, Lee JH
- KMID: 2550318
- Cancer Res Treat.
- 2024 Jan;56(1):1-17.
- doi: 10.4143/crt.2023.562
Radiotherapy (RT) is a fundamental modality in treatment of cervical cancer. With advancement of technology, conventional RT used for external beam radiotherapy (EBRT) for over half a century has been... -
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- GASTric Cancer HER2 Re-Assessment Study 2 (GASTHER2): HER2 Re-assessment for Initially HER2-Negative Advanced Gastric Cancer Patients after Progression on First-Line Treatment
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Hyung J, Kim HD, Ryu MH, Park YS, Moon M, Kang YK
- KMID: 2550336
- Cancer Res Treat.
- 2024 Jan;56(1):199-207.
- doi: 10.4143/crt.2023.490
Purpose Heterogeneous human epidermal growth factor receptor 2 (HER2) overexpression in gastric cancer may lead to a misdiagnosis of HER2 status. Accurate assessment of HER2 status is essential for optimal... -
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- Short-term Impact of Hormone Replacement Therapy on Risk of Breast Cancer in BRCA Mutation Carriers: A Nationwide Study in South Korea
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Kim HY, Park J, Moon SJ, Jeong S, Hong JH, Lee JK, Cho GJ, Cho HW
- KMID: 2550331
- Cancer Res Treat.
- 2024 Jan;56(1):143-148.
- doi: 10.4143/crt.2023.653
Purpose BRCA1/2 mutations are well-known risk factors for breast and ovarian cancers in women. Risk-reducing salpingo-oophorectomy (RRSO) is the standard treatment for preventing ovarian cancer with BRCA mutations. Postmenopausal syndrome... -
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- First-in-Human Phase 1 Study of a B Cell– and Monocyte-Based Immunotherapeutic Vaccine against HER2-Positive Advanced Gastric Cancer
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Jung M, Lee JB, Kim HS, Kwon WS, Kim HO, Kim S, Park M, Kim W, Choi KY, Oh T, Kang CY, Chung HC, Rha SY
- KMID: 2550337
- Cancer Res Treat.
- 2024 Jan;56(1):208-218.
- doi: 10.4143/crt.2022.1328
Purpose BVAC-B is an autologous B cell– and monocyte-based immunotherapeutic vaccine that contains cells transfected with a recombinant human epidermal growth factor receptor 2 (HER2) gene and loaded with the... -
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- Association between Metabolically Healthy Status and Risk of Gastrointestinal Cancer
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Cui H, Tian F, Chen Y, Ma X
- KMID: 2550339
- Cancer Res Treat.
- 2024 Jan;56(1):238-246.
- doi: 10.4143/crt.2023.539
Purpose Although obesity is associated with numerous diseases, the risks of disease may depend on metabolically healthy status. Nevertheless, it is unclear to whether metabolically healthy status affects risk of... -
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- Longitudinal Changes in Smoking Behaviors and Cancer-Related Mortality Risk in Middle-Aged Korean Women
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Tran TXM, Kim S, Kim S, Park B
- KMID: 2550319
- Cancer Res Treat.
- 2024 Jan;56(1):18-26.
- doi: 10.4143/crt.2023.341
Purpose This study investigated association between smoking habit change and cancer-related mortality risk in Korean women. Materials and Methods Study population were women aged ≥ 40 years who underwent two biennial... -
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- Next-Generation Sequencing in Breast Cancer Patients: Real-World Data for Precision Medicine
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Lee H, Cho YA, Kim DG, Cho EY
- KMID: 2550332
- Cancer Res Treat.
- 2024 Jan;56(1):149-161.
- doi: 10.4143/crt.2023.800
Purpose Breast cancer is one of the most common causes of cancer-related death in females. Numerous drug-targetable biomarkers and predictive biomarkers have been developed. Some researchers have expressed doubts about... -
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- Trends and Clinical Characteristics of Next-Generation Sequencing–Based Genetic Panel Tests: An Analysis of Korean Nationwide Claims Data
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Jang M, Pak HY, Heo JY, Lim H, Choi YL, Shim HS, Kim EK
- KMID: 2550320
- Cancer Res Treat.
- 2024 Jan;56(1):27-36.
- doi: 10.4143/crt.2023.844
Purpose In the modern era of precision medicine, next-generation sequencing (NGS) is employed for a variety of clinical purposes. The aim of this study was to investigate the trends and... -
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- Gemcitabine Inhibits the Progression of Pancreatic Cancer by Restraining the WTAP/MYC Chain in an m6A-Dependent Manner
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Cao P, Zhang W, Qiu J, Tang Z, Xue X, Feng T
- KMID: 2550341
- Cancer Res Treat.
- 2024 Jan;56(1):259-271.
- doi: 10.4143/crt.2022.1600
Purpose Pancreatic cancer (PC) is a common malignant tumor of the digestive system, and its 5-year survival rate is only 4%. N6-methyladenosine (m6A) RNA methylation is the most common post-transcriptional... -
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- Risk Factors for Distant Metastasis in Extrahepatic Bile Duct Cancer after Curative Resection (KROG 1814)
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Park Y, Kim TH, Kim K, Yu JI, Jung W, Seong J, Kim WC, Choi JH, Chang AR, Jeong BK, Kim BH, Kim TG, Kim JH, Park HJ, Shin HS, Im JH, Chie EK
- KMID: 2550342
- Cancer Res Treat.
- 2024 Jan;56(1):272-279.
- doi: 10.4143/crt.2023.616
Purpose Risk factors predicting distant metastasis (DM) in extrahepatic bile duct cancer (EHBDC) patients treated with curative resection were investigated. Materials and Methods Medical records of 1,418 EHBDC patients undergoing curative... -
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- Tumor Microenvironment Can Predict Chemotherapy Response of Patients with Triple-Negative Breast Cancer Receiving Neoadjuvant Chemotherapy
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Kim D, Yu Y, Jung KS, Kim YH, Kim JJ
- KMID: 2550333
- Cancer Res Treat.
- 2024 Jan;56(1):162-177.
- doi: 10.4143/crt.2023.330
Purpose Triple-negative breast cancer (TNBC) is a breast cancer subtype that has poor prognosis and exhibits a unique tumor microenvironment. Analysis of the tumor microbiome has indicated a relationship between... -
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- Tumor Microenvironment Modulation by Neoadjuvant Erlotinib Therapy and Its Clinical Impact on Operable EGFR-Mutant Non–Small Cell Lung Cancer
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Ahn BC, Park C, Kim MS, Lee JM, Choi JH, Kim HY, Lee GK, Yu N, Lee Y, Han JY
- KMID: 2550324
- Cancer Res Treat.
- 2024 Jan;56(1):70-80.
- doi: 10.4143/crt.2023.482
Purpose Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors have greatly improved survival in EGFR-mutant (EGFRm) non–small cell lung cancer (NSCLC); however, their effects on the tumor microenvironment (TME) are... -
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- First-Line Alectinib vs. Brigatinib in Advanced Non–Small Cell Lung Cancer with ALK Rearrangement: Real-World Data
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Jeon Y, Park S, Jung HA, Sun JM, Lee SH, Ahn JS, Ahn MJ
- KMID: 2550323
- Cancer Res Treat.
- 2024 Jan;56(1):61-69.
- doi: 10.4143/crt.2023.461
Purpose Alectinib and brigatinib are second-generation anaplastic lymphoma receptor tyrosine kinases (ALKs) that are widely used as first-line therapy for treating ALK-positive advanced non–small cell lung cancer (NSCLC). Given the... -
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- Toremifene, an Alternative Adjuvant Endocrine Therapy, Is Better Than Tamoxifen in Breast Cancer Patients with CYP2D6*10 Mutant Genotypes
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Li X, Li Z, Li L, Liu T, Qian C, Ren Y, Li Z, Chen K, Ji D, Zhang M, Wang J
- KMID: 2550330
- Cancer Res Treat.
- 2024 Jan;56(1):134-142.
- doi: 10.4143/crt.2023.652
Purpose Tamoxifen showed individual differences in efficacy under different CYP2D6*10 genotypes. Our study evaluated the prognosis of tamoxifen or toremifene in hormone receptor (HR)–positive breast cancer patients under different genotypes. Materials... -
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- Strategies to Improve Smoking Cessation for Participants in Lung Cancer Screening Program: Analysis of Factors Associated with Smoking Cessation in Korean Lung Cancer Screening Project (K-LUCAS)
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Kim Y, Lee J, Lee E, Lim J, Kim Y, Lee CT, Jang SH, Paek YJ, Lee WC, Lee CW, Kim HY, Goo JM, Choi KS, Park B, Lee DH, Seo HG
- KMID: 2550326
- Cancer Res Treat.
- 2024 Jan;56(1):92-103.
- doi: 10.4143/crt.2022.1598
Purpose Smoking cessation intervention is one of the key components of successful lung cancer screening program. We investigated the effectiveness and related factors of smoking cessation services provided to the... -
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- Aggressive Local Ablative Radiotherapy Mitigates Progression Risk in Oligometastatic Lung Adenocarcinoma
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Yang G, Kim KH, Lee CG, Hong MH, Kim HR, Cho Y, Yoon HI
- KMID: 2550328
- Cancer Res Treat.
- 2024 Jan;56(1):115-124.
- doi: 10.4143/crt.2023.600
Purpose This study aimed to determine the role of local ablative radiotherapy (LART) in oligometastatic/oligoprogressive lung adenocarcinoma. Materials and Methods Patients (n=176) with oligometastatic lung adenocarcinoma treated with LART were identified,... -
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- Clinical Validation of the Unparalleled Sensitivity of the Novel Allele-Discriminating Priming System Technology–Based EGFR Mutation Assay in Patients with Operable Non–Small Cell Lung Cancer
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Park IH, Son DS, Choi YL, Choi JH, Park JE, Jeon YJ, Cho M, Kim HK, Choi YS, Shim YM, Kang JH, Park S, Lee J, Kim SH, Lee BC, Kim J
- KMID: 2550325
- Cancer Res Treat.
- 2024 Jan;56(1):81-91.
- doi: 10.4143/crt.2023.408
Purpose Recently, we developed allele-discriminating priming system (ADPS) technology. This method increases the sensitivity of conventional quantitative polymerase chain reaction up to 100 folds, with limit of detection, 0.01%, with... -
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- Functional Annotation and Gene Set Analysis of Gastric Cancer Risk Loci in a Korean Population
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Pyun H, Gunathilake M, Lee J, Choi IJ, Kim YI, Sung J, Kim J
- KMID: 2550335
- Cancer Res Treat.
- 2024 Jan;56(1):191-198.
- doi: 10.4143/crt.2022.958
Purpose We aimed to identify the associated single nucleotide polymorphisms (SNPs) with gastric cancer (GC) risk by genome-wide association study (GWAS) and to explore the pathway enrichment of implicated genes... -
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