- Transcription Factors in the Cellular Signaling Network as Prime Targets of Chemopreventive Phytochemicals
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Surh YJ
- KMID: 1804561
- Cancer Res Treat.
- 2004 Oct;36(5):275-286.
Accumulating evidence from epidemiologic and laboratory studies support an inverse relationship between a regular consumption of fruits and vegetables and the risk of specific cancers. Numerous phytochemicals derived from edible... -
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- Elucidation of the Inhibitory Effect of Phytochemicals with Kir6.2 Wild-Type and Mutant Models Associated in Type-1 Diabetes through Molecular Docking Approach
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Jagadeb M, Konkimalla VB, Rath SN, Das RP
- KMID: 2391509
- Genomics Inform.
- 2014 Dec;12(4):283-288.
- doi: 10.5808/GI.2014.12.4.283
Among all serious diseases globally, diabetes (type 1 and type 2) still poses a major challenge to the world population. Several target proteins have been identified, and the etiology causing... -
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- Lipids in Ginseng (Panax ginseng) and Their Analysis
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Kim SH, Kim SY, Choi HK
- KMID: 2409603
- Nat Prod Sci.
- 2018 Mar;24(1):1-12.
- doi: 10.20307/nps.2018.24.1.1
Ginseng (Panax ginseng) is recognized as one of the most valuable medicinal herbs in Asia and it contains diverse phytochemicals that contribute to its pharmacological effects. Although lipids represent a... -
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- Downregulation of Reactive Oxygen Species in Apoptosis
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Jeong CH, Joo SH
- KMID: 2161518
- J Cancer Prev.
- 2016 Mar;21(1):13-20.
- doi: 10.15430/JCP.2016.21.1.13
Generation of reactive oxygen species (ROS) by diverse anti-cancer drugs or phytochemicals has been closely related with the induction of apoptosis in cancers. Also, the downregulation of ROS by these... -
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- Regulation of Neural Stem Cell Fate by Natural Products
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Kim HJ
- KMID: 2432062
- Biomol Ther.
- 2019 Jan;27(1):15-24.
- doi: 10.4062/biomolther.2018.184
Neural stem cells (NSCs) can proliferate and differentiate into multiple cell types that constitute the nervous system. NSCs can be derived from developing fetuses, embryonic stem cells, or induced pluripotent... -
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- Functional Foods in International Market and Its Prospects
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Park KY, Kil JH
- KMID: 2340842
- J Korean Med Assoc.
- 2005 Jun;48(6):529-537.
Nutraceuticals link nutrition with medicine. They cover dietary supplements, functional foods, and medical foods. The definition of functional foods is the foods that promote health and possibly prevention and curing... -
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- Intake of Fruits for Diabetics: Why and How Much?
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Lee EY
- KMID: 2451840
- J Korean Diabetes.
- 2019 Jun;20(2):106-111.
- doi: 10.4093/jkd.2019.20.2.106
Fruits are universally promoted as healthy. Fruits supply dietary fiber, vitamins, minerals and phytochemicals that function as antioxidants. But many people often have concerns that fruit intake has a negative... -
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- The efficacy of phytoestrogen in postmenopausal women
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Park HM
- KMID: 1870350
- Korean J Obstet Gynecol.
- 2007 Mar;50(3):389-415.
Phytoestrogen is a group of phytochemicals called phenolic compounds. Phytoestrogen may be functionally or structurally related to estrogens, resulting in agonistic and antagonistic activity depending upon the tissues. Phytoestrogen may... -
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- Phytochemical Identification from Boehmeria nivea Leaves and Analysis of (-)-Loliolide by HPLC
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Cho S, Lee DG, Jung YS, Kim HB, Cho EJ, Lee S
- KMID: 2328880
- Nat Prod Sci.
- 2016 Jun;22(2):134-139.
- doi: 10.20307/nps.2016.22.2.134
Phytochemicals were isolated from leaves of the fiber crop, ramie (Boehmeria nivea, Bn), using open column chromatography and medium pressure liquid chromatography. Their structures were identified as β-sitosterol, (-)-loliolide, rutin,... -
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- Bioavailability of plant pigment phytochemicals in Angelica keiskei in older adults: A pilot absorption kinetic study
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Correa CR, Chen CY, Aldini G, Rasmussen , Ronchi CF, Berchieri-Ronchi C, Cho SM, Blumberg J, Yeum KJ
- KMID: 2313778
- Nutr Res Pract.
- 2014 Oct;8(5):550-557.
- doi: 10.4162/nrp.2014.8.5.550
BACKGROUND/OBJECTIVES: Angelica keiskei is a green leafy vegetable rich in plant pigment phytochemicals such as flavonoids and carotenoids. This study examined bioavailability of flavonoids and carotenoids in Angelica keiskei and... -
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- Sleep-Aids Derived from Natural Products
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Hu Z, Oh S, Ha TW, Hong JT, Oh KW
- KMID: 2420384
- Biomol Ther.
- 2018 Jul;26(4):343-349.
- doi: 10.4062/biomolther.2018.099
Although drugs such as barbiturates and benzodiazepines are often used for the treatment of insomnia, they are associated with various side effects such as habituations, tolerance and addiction. Alternatively, natural... -
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- Cytotoxic Triterpenoids from the Fruits of Ligustrum japonicum
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Ngo QM, Cao TQ, Woo MH, Min BS, Weon KY
- KMID: 2416068
- Nat Prod Sci.
- 2018 Jun;24(2):93-98.
- doi: 10.20307/nps.2018.24.2.93
Medicinal plants are potential sources of anticancer agents screening. A large number of phytochemicals, including triterpenoids, have been reported to have significant cytotoxic effects on cancer cells. From the fruits... -
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- Galangin (3,5,7-Trihydroxyflavone) Shields Human Keratinocytes from Ultraviolet B-Induced Oxidative Stress
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Madduma Hewage SRK, Piao MJ, Kim KC, Cha JW, Han X, Choi YH, Chae S, Hyun JW
- KMID: 2380350
- Biomol Ther.
- 2015 Mar;23(2):165-173.
- doi: 10.4062/biomolther.2014.130
Most skin damage caused by ultraviolet B (UVB) radiation is owing to the generation of reactive oxygen species. Phytochemicals can act as antioxidants against UVB-induced oxidative stress. This study investigated... -
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- Study on nutritional property and use potential of Gochujang using Gongju chestnuts
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Kim SH
- KMID: 2357141
- J Nutr Health.
- 2016 Oct;49(5):395-399.
- doi: 10.4163/jnh.2016.49.5.395
PURPOSE: Gongju is a famous area for chestnuts, which contain various nutrients and phytochemicals. This study aimed to develop gochujang items using Gongju chestnuts and analyze nutritional properties for the... -
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- Effect of Sasa quelpaertensis Nakai Extracts and its Constituent p-coumaric Acid on the Apoptosis of Human Cancer Cell Lines
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Jang MG, Ko HC, Kim SJ
- KMID: 2432426
- Nat Prod Sci.
- 2018 Dec;24(4):293-297.
- doi: 10.20307/nps.2018.24.4.293
Sasa quelpaertensis Nakai leaves contain a mixture of polysaccharides, amino acids, and polyphenols, which mediate various biological activities. For efficient utilization of its leaf, we reported the preparation procedure for... -
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- Antitumor Effects of Genipin: New and Emerging Insights from Recent Studies
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Shin YS, Cho M, Park GH, Cho H, Kang H
- KMID: 2327907
- J Bacteriol Virol.
- 2016 Jun;46(2):108-113.
- doi: 10.4167/jbv.2016.46.2.108
Genipin, an aglycone derived from geniposide found in Gardenia jasminoides, is known to be an excellent natural cross-linker, strong apoptosis inducer, and antiviral agent. Although evidence suggests antiviral activity of... -
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- 3,3'-Diindolylmethane Inhibits Flt3L/GM-CSF-induced-bone Marrow-derived CD103+ Dendritic Cell Differentiation Regulating Phosphorylation of STAT3 and STAT5
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Park JH, Choi AJ, Kim SJ, Jeong SY
- KMID: 2132702
- Immune Netw.
- 2015 Dec;15(6):278-290.
- doi: 10.4110/in.2015.15.6.278
The intestinal immune system maintains oral tolerance to harmless antigens or nutrients. One mechanism of oral tolerance is mediated by regulatory T cell (Treg)s, of which differentiation is regulated by... -
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- Pharmacological Activities and Applications of Spicatoside A
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Ramalingam M, Kim SJ
- KMID: 2351669
- Biomol Ther.
- 2016 Sep;24(5):469-474.
- doi: 10.4062/biomolther.2015.214
Liriopogons (Liriope and Opiopogon) species are used as a main medicinal ingredient in several Asian countries. The Liriopes Radix (tuber, root of Liriope platyphylla) has to be a promising candidate... -
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- APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functions
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Thakur S, Sarkar B, Cholia RP, Gautam N, Dhiman M, Mantha AK
- KMID: 2155371
- Exp Mol Med.
- 2014 Jul;46(7):e106.
- doi: 10.1038/emm.2014.42
Apurinic/apyrimidinic endonuclease 1 (APE1) is a multifunctional enzyme involved in the base excision repair (BER) pathway, which repairs oxidative base damage caused by endogenous and exogenous agents. APE1 acts as... -
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- Identification of Suitable Natural Inhibitor against Influenza A (H1N1) Neuraminidase Protein by Molecular Docking
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Sahoo M, Jena L, Rath SN, Kumar S
- KMID: 2353661
- Genomics Inform.
- 2016 Sep;14(3):96-103.
- doi: 10.5808/GI.2016.14.3.96
The influenza A (H1N1) virus, also known as swine flu is a leading cause of morbidity and mortality since 2009. There is a need to explore novel anti-viral drugs for... -
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