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Posterior Circulation Stroke: Advances in Understanding and Management

Donnan GA

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Residual Risk and Its Risk Factors for Ischemic Stroke with Adherence to Guideline-Based Secondary Stroke Prevention

Pan Y, Li Z, Li J, Jin A, Lin J, Jing J, Li H, Meng X, Wang Y, Wang Y

Background and Purpose Despite administration of evidence-based therapies, residual risk of stroke recurrence persists. This study aimed to evaluate the residual risk of recurrent stroke in acute ischemic stroke or...
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Clinical Outcomes of Mechanical Thrombectomy in Stroke Tandem Lesions According to Intracranial Occlusion Location

Zapata-Arriaza E, Albóniga-Chindurza Ad, Ortega-Quintanilla J, Escudero-Martínez I, Moniche F, Medina-Rodríguez M, Pardo-Galiana B, Rodríguez JAC, Hernández LL, Ainz L, Pérez-Sánchez S, Domínguez-Mayoral A, Barragán A, Cayuela A, Montaner J, García AG

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Early Fluid Attenuation Inversion Recovery Sulcal Contrast Enhancement Correlates with Severity of Reversible Cerebral Vasoconstriction Syndrome

Itsekson-Hayosh Z, Tsarfaty G, Greenberg G, Sharon M, Bakon M, Wohl A, Chapman J, Orion D

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Tobacco Use: A Major Risk Factor of Intracerebral Hemorrhage

Cho S, Rehni AK, Dave KR

Spontaneous intracerebral hemorrhage (sICH) is one of the deadliest subtypes of stroke, and no treatment is currently available. One of the major risk factors is tobacco use. In this article,...
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Eighteen-Year Disease Progression and Survival in CADASIL

Gravesteijn G, Hack RJ, Opstal AMv, van Eijsden BJ, Middelkoop HA, Rodriguez Girondo MD, Aartsma-Rus A, Grond Jvd, Rutten JW, Oberstein SAL

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Perfusion and Diffusion Variables Predict Early Neurological Deterioration in Minor Stroke and Large Vessel Occlusion

Gwak DS, Kwon JA, Shim DH, Kim YW, Hwang YH

Background and Purpose Patients with acute large vessel occlusion (LVO) presenting with mild stroke symptoms are at risk of early neurological deterioration (END). This study aimed to identify the optimal...
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Development and Testing of Thrombolytics in Stroke

Nikitin D, Choi S, Mican J, Toul M, Ryu WS, Damborsky J, Mikulik R, Kim DE

Despite recent advances in recanalization therapy, mechanical thrombectomy will never be a treatment for every ischemic stroke because access to mechanical thrombectomy is still limited in many countries. Moreover, many...
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Delayed Lesions on Diffusion-Weighted Imaging in Initially Lesion-Negative Stroke Patients

Kim K, Kim BJ, Huh J, Yang SK, Yang MH, Han MK, Jung C, Choi BS, Kim JH, Bae HJ

Background and Purpose Lesions on diffusion-weighted imaging (DWI) occasionally appear on follow-up magnetic resonance imaging (MRI) among initially DWI-negative but clinically suspicious stroke patients. We established the prevalence of positive...
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Health Economic Impact of First Pass Success: An Asia-Pacific Cost Analysis of the ARISE II Study

Yeo L, Zaidat OO, Saver JL, Mattle HP, Lee SHY, Kottenmeier E, Cameron HL, Qadeer RA, Andersson T

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Role of Blood Pressure Management in Stroke Prevention: A Systematic Review and Network Meta-Analysis of 93 Randomized Controlled Trials

Zhong XL, Dong Y, Xu W, Huang YY, Wang HF, Zhang TS, Sun L, Tan L, Dong Q, Yu JT

Background and Purpose The present study aimed to compare the efficacy and tolerability of different blood pressure (BP)-lowering strategies. Methods Randomized controlled trials that compared various antihypertensive treatments and stroke outcomes...
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Initiation of Guideline-Matched Oral Anticoagulant in Atrial Fibrillation-Related Stroke

Eun MY, Kim JY, Hwang YH, Park MS, Kim JT, Choi KH, Jung JM, Yu S, Kim CK, Oh K, Song TJ, Kim YJ, Kim BJ, Heo SH, Park KY, Kim JM, Park JH, Choi JC, Chung JW, Bang OY, Kim GM, Seo WK

Background and Purpose To evaluate the outcome events and bleeding complications of the European Society of Cardiology (ESC) guideline-matched oral anticoagulant therapy for patients with acute ischemic stroke and atrial...
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General Anesthesia versus Conscious Sedation in Mechanical Thrombectomy

Feil K, Herzberg M, Dorn F, Tiedt S, Küpper C, Thunstedt DC, Hinske LC, Mühlbauer K, Goss S, Liebig T, Dieterich M, Bayer A, Kellert L, on Behalf of the GSR Investigators

Background and Purpose Anesthesia regimen in patients undergoing mechanical thrombectomy (MT) is still an unresolved issue. Methods We compared the effect of anesthesia regimen using data from the German Stroke Registry-Endovascular...
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Golden Hour Thrombolysis in Acute Ischemic Stroke: The Changing Pattern in South Korea

Kim H, Kim JT, Lee JS, Kim BJ, Park JM, Kang K, Lee SJ, Kim JG, Cha JK, Kim DH, Park TH, Park SS, Lee KB, Lee J, Hong KS, Cho YJ, Park HK, Lee BC, Yu KH, Oh MS, Kim DE, Ryu WS, Choi JC, Kwon JH, Kim WJ, Shin DI, Sohn SI, Hong JH, Park MS, Choi KH, Cho KH, Lee J, Bae HJ

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Cilostazol and Probucol for Cognitive Decline after Stroke: A Cognitive Outcome Substudy of the PICASSO Trial

Lim JS, Kwon SU, Yu KH, Yu S, Park JH, Lee BC, Oh MS, Kim YJ, Rha JH, Hwang YH, Lee JS, Heo SH, Ahn SH, Seo WK, Park JM, Lee JH, Kwon JH, Sohn SI, Jung JM, Kim HY, Kim EG, Cha JK, Park MS, Nam HS, Bae HJ, Kim DE, Park J, Kang Y, Choi J, Lee J

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Dual-Energy CT Angiography Improves Accuracy of Spot Sign for Predicting Hematoma Expansion in Intracerebral Hemorrhage

Peeters MT, Kort KJd, Houben R, Henneman WJ, Oostenbrugge RJv, Staals J, Postma AA

Background and Purpose Spot sign (SS) on computed tomography angiography (CTA) is associated with hematoma expansion (HE) and poor outcome after intracerebral hemorrhage (ICH). However, its predictive performance varies across...
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Safety and Angiographic Efficacy of Intra-Arterial Fibrinolytics as Adjunct to Mechanical Thrombectomy: Results from the INFINITY Registry

Kaesmacher J, Abdullayev N, Maamari B, Dobrocky T, Vynckier J, Piechowiak EI, Pop R, Behme D, Sporns PB, Styczen H, Virtanen P, Meyer L, Meinel TR, Cantré D, Kabbasch C, Maus V, Pekkola J, Fischer S, Hasiu A, Schwarz A, Wildgruber M, Seiffge DJ, Langner S, Martinez-Majander N, Radbruch A, Schlamann M, Mihoc D, Beaujeux R, Strbian D, Fiehler J, Mordasini P, Gralla J, Fischer U

Background and Purpose Data on safety and efficacy of intra-arterial (IA) fibrinolytics as adjunct to mechanical thrombectomy (MT) are sparse. Methods INtra-arterial FIbriNolytics In ThrombectomY (INFINITY) is a retrospective multi-center observational...
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