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Atypical Subtrochanteric Femur Fracture in Patient with Metastatic Breast Cancer Treated with Zoledronic Acid

Kim YS, Park WC

Several case series have suggested an association exists between atypical femoral subtrochanteric fractures and long-term use of bisphosphonates. It is thought that prolonged use of bisphosphonates may lead to adynamic,...
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Giant Breast Involvement in Acute Lymphoblastic Leukemia: MRI Findings

Basara I, Orguc S

Breast metastases in cases of leukemia are rare. We aimed to report the conventional-advanced magnetic resonance imaging (MRI) findings of unilateral breast involvement of acute lymphoblastic leukemia (ALL) and review...
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MRI Findings of Large Low-Grade Angiosarcoma of the Breast with Subsequent Bone Metastases: A Case Report

Cucci E, Ciuffreda , Tambaro R, Aquilani L, Barrassi M, Sallustio

We describe the magnetic resonance imaging (MRI) findings of 13 cm-sized low-grade angiosarcoma of the breast that occurred in a 23-year-old woman. Magnetic resonance examination revealed an ill-defined mass with...
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An Incidentally Detected Breast Cancer on Tc-99m MIBI Cardiac Scintigraphy

Seker D, Seker G, Ozturk E, Bayar B, Kulacoglu

Tc-99m methoxyisobutylisonitrile (MIBI) scintigraphy is generally used as a second-line diagnostic tool for obscured breast lesions. When the entire field of view is examined carefully, it is often possible to...
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Synchronous Bilateral Male Breast Cancer: A Case Report

Sun WY, Lee KH, Lee HC, Ryu DH, Park JW, Yun HY, Song YJ

Synchronous bilateral breast cancer is extremely rare in men and has not, up to date, been reported in Korea. A 54-year-old man presented with a palpable mass in the right...
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Breast Metastasis from Renal Cell Carcinoma: Rare Initial Presentation of Disease Recurrence after 5 Years

Mahrous M, Al Morsy W, Al-Hujaily A, AL-Sulimani S

Metastasis to the breast from extra-mammary tumors is rare with only a few sporadic cases reported. We present a 58-year-old female patient diagnosed with renal cell carcinoma. Five years ago...
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Survey of the Application of the Korean Clinical Practice Recommendations on Breast Cancer Treatment: The Utility of the Korean Breast Cancer Society Guidelines

Gwak G, Lee HK, Kim HJ, Lee SY, Park YL, Lee JW, Kim SG, Huh H, Shin H, Kim JR, Ahn JS, Son JH, Lee IG, Park WC, Kim SY, Han S, Lee ES, Korean Breast Cancer Society, Korea Breast Cancer Foundation

This survey was performed to analyze the usability of the third edition of the Korean breast cancer clinical practice guidelines (KBCCPG) in clinical practice. We made a questionnaire composed of...
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Development of Novel Breast Cancer Recurrence Prediction Model Using Support Vector Machine

Kim W, Kim KS, Lee JE, Noh DY, Kim SW, Jung YS, Park MY, Park RW

PURPOSE: The prediction of breast cancer recurrence is a crucial factor for successful treatment and follow-up planning. The principal objective of this study was to construct a novel prognostic model...
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Long-Term Follow-Up Result of Benign Phyllodes Tumor of the Breast Diagnosed and Excised by Ultrasound-Guided Vacuum-Assisted Breast Biopsy

Park HL, Kwon SH, Chang SY, Huh JY, Kim JY, Shim JY, Lee YH

PURPOSE: Percutaneous removal of benign breast tumors using ultrasound-guided vacuum-assisted breast biopsy (VABB) has been recently regarded as a feasible and safe method without serious complications. The aim of this...
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The Risk Factors Influencing between the Early and Late Recurrence in Systemic Recurrent Breast Cancer

Song WJ, Kim KI, Park SH, Kwon MS, Lee TH, Park HK, An JS

PURPOSE: Patients with recurrent breast cancer usually die of their disease, even after radical surgery and adjuvant therapies which could reduce the odds of dying. Many studies analyzed and compared...
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Efficiency of Ultrasound and Ultrasound-Guided Fine Needle Aspiration Cytology in Preoperative Assessment of Axillary Lymph Node Metastases in Breast Cancer

Oz A, Demirkazik FB, Akpinar MG, Soygur I, Baykal A, Onder SC, Uner A

PURPOSE: We performed this study to detect preoperative axillary metastases with ultrasound (US)-guided fine needle aspiration biopsy (FNAB), to eliminate the need for time-consuming and costly sentinel lymph node (SLN)...
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Impact of Immunohistochemistry-Based Molecular Subtype on Chemosensitivity and Survival in Patients with Breast Cancer Following Neoadjuvant Chemotherapy

Yoo C, Ahn JH, Jung KH, Kim SB, Kim HH, Shin HJ, Ahn SH, Son BH, Gong G

PURPOSE: Pathologic complete response (pCR) has been suggested as a surrogate prognostic indicator in breast cancer patients treated with neoadjuvant chemotherapy. We assessed whether the likelihood of pCR and survival...
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Impact of Triple-Negative Breast Cancer Phenotype on Prognosis in Patients with Stage I Breast Cancer

Kim JE, Ahn HJ, Ahn JH, Yoon DH, Kim SB, Jung KH, Gong GY, Kim MJ, Son BH, Ahn SH

PURPOSE: Although most patients with stage I breast cancer have a good prognosis, their clinical outcomes may vary significantly. We assessed clinical outcomes and prognostic factors in stage I breast...
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The Predictive Value of Serum HER2/neu for Response to Anthracycline-Based and Trastuzumab-Based Neoadjuvant Chemotherapy

Lee JS, Son BH, Ahn SH

PURPOSE: Little information exists about the possible influence of serum HER2/neu on response to chemotherapy. We propose that the assessment of serum HER2/neu in a pretreatment serum sample may be...
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The Role of Neutrophil Estrogen Receptor Status on Maspin Synthesis via Nitric Oxide Production in Human Breast Cancer

Ganguly Bhattacharjee K, Bhattacharyya M, Halder UC, Jana P, Sinha AK

PURPOSE: Estrogen, through its binding to nuclear estrogen receptor (ER), has been implicated in the development of human breast cancer. The presence or absence of ER in breast lesions has...
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The Glycolytic Phenotype is Correlated with Aggressiveness and Poor Prognosis in Invasive Ductal Carcinomas

Jang SM, Han H, Jang KS, Jun YJ, Jang SH, Min KW, Chung MS, Paik SS

PURPOSE: Glucose uptake and glycolytic metabolism are enhanced in cancer cells, and increased expression of glucose transporter 1 (GLUT1) has also been reported. The aim of this study was to...
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Overexpression of Cell Cycle Progression Inhibitor Geminin is Associated with Tumor Stem-Like Phenotype of Triple-Negative Breast Cancer

Di Bonito , Cantile M, Collina F, Scognamiglio G, Cerrone M, La Mantia , Barbato A, Liguori G, Botti G

PURPOSE: Triple-negative breast cancer, has a significant clinical relevance being associated with a shorter median time to relapse and death and does not respond to endocrine therapy or other available...
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Association of Alanine-Valine Manganese Superoxide Dismutase Gene Polymorphism and Microheterogeneity Manganese Superoxide Dismutase Activity in Breast Cancer and Benign Breast Tissue

Atoum M, Abdel-Fattah M, Nimer N, Abdel-Rahman S, Abdeldayem SA

PURPOSE: Although the etiology of breast cancer is multifactorial, oxidative stress plays an important role in carcinogenesis. In this study, manganese superoxide dismutase (MnSOD) gene polymorphism and activity were evaluated...
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Breast Cancer as an Acquired Thrombophilic State

Kyriazi V

Cancer is an acquired thrombophilic condition manifested by increased incidence of venous and arterial thromboembolic complications. Despite progress that has been achieved in treatments over the recent years, thromboembolism remains...
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Enhanced Radiosensitivity and Chemosensitivity of Breast Cancer Cells by 2-Deoxy-D-Glucose in Combination Therapy

Aghaee F, Pirayesh Islamian J, Baradaran

Breast cancer is the most common malignancy, and it is also the major cause of cancer-related deaths of women worldwide. Breast cancer treatment involves surgery, chemotherapy, radiation therapy, or combination...
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