J Breast Cancer.  2012 Jun;15(2):248-251. 10.4048/jbc.2012.15.2.248.

Synchronous Bilateral Male Breast Cancer: A Case Report

• Sun WY
• Lee KH
• Lee HC
• Ryu DH
• Park JW
• Yun HY
• Song YJ

• KMID: 2242199
• DOI: http://doi.org/10.4048/jbc.2012.15.2.248

Abstract

Synchronous bilateral breast cancer is extremely rare in men and has not, up to date, been reported in Korea. A 54-year-old man presented with a palpable mass in the right breast. The right nipple was retracted and bilateral axillary accessory breasts and nipples were present. On physical examination, a 2 cm-sized mass was palpated directly under the right nipple, and, with squeezing, bloody discharge developed in a single duct of the left nipple. There was no palpable mass in the left breast, and axillary lymph nodes were not palpable. Physical examination of external genitalia revealed a unilateral undescended testis on the left side. Synchronous bilateral breast cancer was diagnosed using mammography, ultrasonography, and core-needle biopsy. Histopathological examination revealed invasive ductal carcinoma in the right breast and ductal carcinoma in situ in the left breast. Bilateral total mastectomy, sentinel lymph node biopsy, and excision of accessory breasts in the axilla were performed.

Keyword

Breast; Male; Synchronous neoplasms

MeSH Terms

Axilla
Biopsy
Breast
Breast Neoplasms
Carcinoma, Ductal
Carcinoma, Intraductal, Noninfiltrating
Cryptorchidism
Genitalia
Humans
Korea
Lymph Nodes
Male
Mammography
Mastectomy, Simple
Middle Aged
Neoplasms, Multiple Primary
Nipples
Nitriles
Physical Examination
Pyrethrins
Sentinel Lymph Node Biopsy
Nitriles
Pyrethrins

Figure

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  Figure 1 A mass (arrowheads) with nipple retraction was detected in the right breast. Bilateral accessory breasts in the axilla with nipples (arrows) were also present. (A) Right. (B) Left.

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  Figure 2 Mammography showed a mass in the subareolar area of both breasts. (A) Right. (B) Left.

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  Figure 3 Ultrasonography showed a hypoechoic breast mass (BIRADS Category 5) in the subareolar area of both breasts. (A) Right. (B) Left.

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  Figure 4 Positron emission tomography/computed tomography showed bilateral uptake in the subareolar area. SUVmax was 6.8 in the right breast and 5.2 in the left breast.

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  Figure 5 (A) The invasive ductal carcinoma in the right breast was mainly composed of micropapillary components (H&E stain, ×200). The tumor cells were suspended in a clear space. (B) The solid papillary carcinoma in the left breast showed solid tumor cell nests with focal necrosis (H&E stain, ×100).

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