- Exploring Renal Pyruvate Metabolism as a Therapeutic Avenue for Diabetic Kidney Injury
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Lee J
- KMID: 2555769
- Diabetes Metab J.
- 2024 May;48(3):385-386.
- doi: 10.4093/dmj.2024.0210
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- Does Rosuvastatin/Ezetimibe Combination Therapy Offer Potential Benefits for Glucose Metabolism beyond Lipid-Lowering Efficacy in T2DM?
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Park IR, Moon JS
- KMID: 2555770
- Diabetes Metab J.
- 2024 May;48(3):387-389.
- doi: 10.4093/dmj.2024.0168
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- Glucagon-Like Peptide-1: New Regulator in Lipid Metabolism
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Bu T, Sun Z, Pan Y, Deng X, Yuan G
- KMID: 2555767
- Diabetes Metab J.
- 2024 May;48(3):354-372.
- doi: 10.4093/dmj.2023.0277
Glucagon-like peptide-1 (GLP-1) is a 30-amino acid peptide hormone that is mainly expressed in the intestine and hypothalamus. In recent years, basic and clinical studies have shown that GLP-1 is... -
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- Insulin Resistance, Non-Alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus: Clinical and Experimental Perspective
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Jung I, Koo DJ, Lee WY
- KMID: 2555765
- Diabetes Metab J.
- 2024 May;48(3):327-339.
- doi: 10.4093/dmj.2023.0350
It has been generally accepted that insulin resistance (IR) and reduced insulin secretory capacity are the basic pathogenesis of type 2 diabetes mellitus (T2DM). In addition to genetic factors, the... -
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- Clinical Characteristics of Diabetes in People with Mitochondrial DNA 3243A>G Mutation in Korea
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Rho EH, Baek SI, Lee H, Seong MW, Chae JH, Park KS, Kwak SH
- KMID: 2555779
- Diabetes Metab J.
- 2024 May;48(3):482-486.
- doi: 10.4093/dmj.2023.0078
Maternally inherited diabetes and deafness (MIDD) is a rare mitochondrial disorder primarily resulting from m.3243A>G mutation. The clinical characteristics of MIDD exhibit significant heterogeneity. Our study aims to delineate these... -
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- Roles of Histone Deacetylase 4 in the Inflammatory and Metabolic Processes
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Kang H, Park YK, Lee JY, Bae M
- KMID: 2555766
- Diabetes Metab J.
- 2024 May;48(3):340-353.
- doi: 10.4093/dmj.2023.0174
Histone deacetylase 4 (HDAC4), a class IIa HDAC, has gained attention as a potential therapeutic target in treating inflammatory and metabolic processes based on its essential role in various biological... -
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- Optimal Coefficient of Variance Threshold to Minimize Hypoglycemia Risk in Individuals with Well-Controlled Type 1 Diabetes Mellitus
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Yoo JH, Yang SH, Jin SM, Kim JH
- KMID: 2555774
- Diabetes Metab J.
- 2024 May;48(3):429-439.
- doi: 10.4093/dmj.2023.0083
Background: This study investigated the optimal coefficient of variance (%CV) for preventing hypoglycemia based on real-time continuous glucose monitoring (rt-CGM) data in people with type 1 diabetes mellitus (T1DM) already... -
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- Switching from Conventional Fibrates to Pemafibrate Has Beneficial Effects on the Renal Function of Diabetic Subjects with Chronic Kidney Disease
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Izumihara R, Nomoto H, Kito K, Yamauchi Y, Omori K, Shibayama Y, Yanagiya S, Miya A, Kameda H, Cho KY, Nagai S, Sakuma I, Nakamura A, Atsumi T, on Behalf of the PARM-T2D Study Group
- KMID: 2555778
- Diabetes Metab J.
- 2024 May;48(3):473-481.
- doi: 10.4093/dmj.2023.0370
Background: Fibrates have renal toxicity limiting their use in subjects with chronic kidney disease (CKD). However, pemafibrate has fewer toxic effects on renal function. In the present analysis, we evaluated... -
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- 2023 Diabetic Kidney Disease Fact Sheet in Korea
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Kim NH, Seo MH, Jung JH, Han KD, Kim MK, Kim NH, on Behalf of Diabetic Kidney Disease Research Group of the Korean Diabetes Association
- KMID: 2555777
- Diabetes Metab J.
- 2024 May;48(3):463-472.
- doi: 10.4093/dmj.2023.0310
Background: To investigate the prevalence, incidence, comorbidities, and management status of diabetic kidney disease (DKD) and diabetes-related end-stage kidney disease (ESKD) in South Korea. Methods: We used the Korea National Health... -
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- Epicardial Adipose Tissue and Heart Failure, Friend or Foe?
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Cho DH, Park SM
- KMID: 2555768
- Diabetes Metab J.
- 2024 May;48(3):373-384.
- doi: 10.4093/dmj.2023.0190
Heart failure (HF) management guidelines recommend individualized assessments based on HF phenotypes. Adiposity is a known risk factor for HF. Recently, there has been an increased interest in organ-specific adiposity,... -
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- Supplementation of Clostridium butyricum Alleviates Vascular Inflammation in Diabetic Mice
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Zhou T, Qiu S, Zhang L, Li Y, Zhang J, Shen D, Zhao P, Yuan L, Zhao L, Duan Y, Xing C
- KMID: 2555771
- Diabetes Metab J.
- 2024 May;48(3):390-404.
- doi: 10.4093/dmj.2023.0109
Background: Gut microbiota is closely related to the occurrence and development of diabetes and affects the prognosis of diabetic complications, and the underlying mechanisms are only partially understood. We aimed... -
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- Safety and Effectiveness of Dulaglutide in the Treatment of Type 2 Diabetes Mellitus: A Korean Real-World Post-Marketing Study
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Han J, Lee WJ, Hur KY, Cho JH, Lee BW, Park CY
- KMID: 2555773
- Diabetes Metab J.
- 2024 May;48(3):418-428.
- doi: 10.4093/dmj.2023.0030
Background: To investigate the real-world safety and effectiveness of dulaglutide in Korean adults with type 2 diabetes mellitus (T2DM). Methods: This was a real-world, prospective, non-interventional post-marketing safety study conducted from... -
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- Reducing Oxidative Stress and Inflammation by Pyruvate Dehydrogenase Kinase 4 Inhibition Is Important in Prevention of Renal Ischemia-Reperfusion Injury in Diabetic Mice
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Khang AR, Kim DH, Kim MJ, Oh CJ, Jeon JH, Choi SH, Lee IK
- KMID: 2555772
- Diabetes Metab J.
- 2024 May;48(3):405-417.
- doi: 10.4093/dmj.2023.0196
Background: Reactive oxygen species (ROS) and inflammation are reported to have a fundamental role in the pathogenesis of ischemia-reperfusion (IR) injury, a leading cause of acute kidney injury. The present... -
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- Harnessing Metabolic Indices as a Predictive Tool for Cardiovascular Disease in a Korean Population without Known Major Cardiovascular Event
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Kim HJ, Kim BS, Lee Y, Ahn SB, Kim DW, Shin JH
- KMID: 2555776
- Diabetes Metab J.
- 2024 May;48(3):449-462.
- doi: 10.4093/dmj.2023.0197
Background: This study evaluated the usefulness of indices for metabolic syndrome, non-alcoholic fatty liver disease (NAFLD), and insulin resistance (IR), as predictive tools for cardiovascular disease in middle-aged Korean adults. Methods:... -
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- Glycemic Control Is Associated with Histological Findings of Nonalcoholic Fatty Liver Disease
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Miyake T, Furukawa S, Matsuura B, Yoshida O, Miyazaki M, Shiomi A, Kanamoto A, Nakaguchi H, Nakamura Y, Imai Y, Koizumi M, Watanabe T, Yamamoto Y, Koizumi Y, Tokumoto Y, Hirooka M, Kumagi T, Takesita E, Ikeda Y, Abe M, Hiasa Y
- KMID: 2555775
- Diabetes Metab J.
- 2024 May;48(3):440-448.
- doi: 10.4093/dmj.2023.0200
Background: Poor lifestyle habits may worsen nonalcoholic fatty liver disease (NAFLD), with progression to nonalcoholic steatohepatitis (NASH) and cirrhosis. This study investigated the association between glycemic control status and hepatic... -
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