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A Case of Brain Abscess Caused by the Dematiaceous Mold Neoscytalidium dimidiatum in a Korean Man

Jo SY, Lee S, Kim KH, Yi J

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A Case of IgG4-related Disease With Bone Marrow Involvement: Bone Marrow Findings and Flow Cytometric Immunophenotyping of Plasma Cells

Kim HJ, You E, Hong S, Park CJ

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der(1)t(1;1)(p36;q10) as a Rare Variant of 1q Gain in Fanconi Anemia-Associated Myelodysplastic Syndrome

Safavi M, Vasei M

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Osteomyelitis Caused by Hypervirulent Klebsiella pneumoniae: The First Korean Case With Family Spread

Lee CH, Chae JD, Choe W, Lee HY, Sohn YH, Ihm C, Jeong JH

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Development of Crohn’s Disease in a Child With SLC26A3-related Congenital Chloride Diarrhea: Report of the First Case in East Asia and a Novel Missense Variant

Kim ES, Song JS, Ki CS, Choe YH, Kang B

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Sustainability in Healthcare: Perspectives and Reflections Regarding Laboratory Medicine

Molero A, Calabrò M, Vignes M, Gouget B, Gruson D

Healthcare structures serve to protect and improve public health; however, they can have negative effects on human well-being and the environment. Thus, sustainability is an important target in a rapidly...
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Schemes and Performance Evaluation Criteria of Korean Association of External Quality Assessment (KEQAS) for Improving Laboratory Testing

Kim S, Lee K, Park HD, Lee YW, Chun S, Min WK

External quality assessment (EQA) is important for evaluating clinical laboratories and enhancing their testing quality. EQA schemes are variable; thus, it is crucial that the EQA organizers share their experiences...
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Laboratory Diagnostic Methods for Clostridioides difficile Infection: the First Systematic Review and Meta-analysis in Korea

Chung HS, Park JS, Shin BM

Background: Various methods are used for the diagnosis of Clostridioides difficile infection (CDI). We systematically analyzed and investigated the performance of current laboratory diagnostic methods for CDI. Methods: We performed systematic...
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Establishment of Pediatric Reference Intervals for Routine Laboratory Tests in Korean Population: A Retrospective Multicenter Analysis

Sung JY, Seo JD, Ko DH, Park MJ, Hwang SM, Oh S, Chun S, Seong MW, Song J, Song SH, Park SS

Background: Reference intervals defined for adults or children of other ethnicities cannot be applied in the evaluation of Korean pediatric patients. Pediatric reference intervals are difficult to establish because children...
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Surveillance of Coronavirus Disease 2019 (COVID-19) Testing in Clinical Laboratories in Korea

Huh HJ, Hong KH, Kim TS, Song SH, Roh KH, Lee H, Kwon GC

In response to the ongoing coronavirus disease 2019 (COVID-19) pandemic, an online laboratory surveillance system was established to monitor severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) real-time reverse transcription-PCR (rRT-PCR)...
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Utility of an Automatic Vision-Based Examination System (AVE-562) for the Detection of Clonorchis sinensis Eggs in Stool

Lee YJ, Won EJ, Cho YC, Kim SH, Shin MG, Shin JH

Stool examination is the gold standard for the detection of intestinal parasites. We assessed the performance of a newly developed AVE-562 analyzer (AVE Science & Technology Co., Hunan, China) for...
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Targeted Next-Generation Sequencing of Plasma CellFree DNA in Korean Patients with Hepatocellular Carcinoma

Chae H, Sung PS, Choi H, Kwon A, Kang D, Kim Y, Kim M, Yoon SK

Background: Hepatocellular carcinoma (HCC) is the second-most-common cause of cancer-related deaths worldwide, and an accurate and non-invasive biomarker for the early detection and monitoring of HCC is required. We assessed...
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Prediction of HLA-DQ in Deceased Donors and its Clinical Significance in Kidney Transplantation

Kim SK, Yang JJ, Hwang SH, Sung H, Shin S, Ko SY, Oh HB

Background: HLA-DQ typing in deceased donors is not mandatory in Korea. Therefore, when patients develop DQ antibodies after kidney transplantation (KT) from deceased donor, it is impossible to determine whether...
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Performance Evaluation of VITEK MS for the Identification of a Wide Spectrum of Clinically Relevant Filamentous Fungi Using a Korean Collection

Shin JH, Kim SH, Lee D, Lee SY, Chun S, Lee JH, Won EJ, Choi HJ, Choi HW, Kee SJ, Shin MG, Shin JH

The correct identification of filamentous fungi is challenging. We evaluated the performance of the VITEK MS v3.0 system (bioMérieux, Marcy-l’Étoile, France) for the identification of a wide spectrum of clinically...
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Relationship Between Rotavirus P[6] Infection in Korean Neonates and Histo-Blood Group Antigen: a Single-Center Study

Lee SK, Oh SJ, Choi S, Choi SH, Shin SH, Lee EJ, Cho EJ, Hyun J, Kim HS

Background: Rotaviruses are a major cause of pediatric gastroenteritis. The rotavirus P[6] genotype is the most prevalent genotype isolated from Korean neonates but has rarely been reported in other countries....
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Role of Genetic Variants and Gene Expression in the Susceptibility and Severity of COVID-19

Choudhary S, Sreenivasulu K, Mitra P, Misra S, Sharma P

Since its first report in December 2019, coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly emerged as a pandemic affecting nearly all countries...
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Quantification of Thioguanine in DNA Using Liquid Chromatography-Tandem Mass Spectrometry for Routine Thiopurine Drug Monitoring in Patients With Pediatric Acute Lymphoblastic Leukemia

Choi R, Chun MR, Park J, Lee JW, Ju HY, Cho HW, Hyun JK, Koo HH, Yi ES, Lee SY

Background: We developed an assay to measure DNA-incorporated 6-thioguanine (DNATG) and validated its clinical applicability in Korean pediatric patients with acute lymphoblastic leukemia (ALL) in order to improve individualized thiopurine...
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Genotypic and Phenotypic Characteristics of Hereditary Leiomyomatosis and Renal Cell Cancer Syndrome in Korean Patients

Seo JY, Ahn JY, Keam B, Kim M, Yoon S, Lee JL, Park K, Park I

Background: Hereditary leiomyomatosis and renal cell cancer (HLRCC) is an autosomal dominant cancer predisposition syndrome. HLRCC is characterized by the development of cutaneous leiomyomas, early-onset uterine leiomyomas, and HLRCC-associated renal...
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