Ann Lab Med.  2021 Mar;41(2):247-249. 10.3343/alm.2021.41.2.247.

A Case of Brain Abscess Caused by the Dematiaceous Mold Neoscytalidium dimidiatum in a Korean Man

Affiliations
  • 1Department of Laboratory Medicine, Pusan National University Yangsan Hospital, Yangsan, Korea
  • 2Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea
  • 3Department of Laboratory Medicine, Pusan National University School of Medicine, Busan, Korea
  • 4Department of Laboratory Medicine, Pusan National University Hospital, Busan, Korea


Figure

  • Fig. 1 Culture of the Neoscytalidium dimidiatum brain isolate on Sabouraud dextrose agar. (A) After incubation for three days, the isolate showed white woolly and dark brown to black pigmented colonies filling the agar. (B) Microscopic examination of the N. dimidiatum isolate (× 400). A cellophane tape mount with lactophenol cotton blue stain demonstrated septate hyphae and numerous rectangular arthroconidia (arrow). The arthroconidia and some hyphae were brown.

  • Fig. 2 Phylogenetic analysis of the isolate from this study and closely related Neoscytalidium spp. Botrysphaeria dothidea sequences were used as an outgroup. The isolate from this study is marked with ‘Author’ after the species name. (A) Internal transcribed spacer sequences. (B) Sequences of the D1/D2 region of large subunit ribosomal RNA.


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