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Trends in Heart Valve Surgery in Korea: A Report from the Heart Valve Surgery Registry Database

Choi JW, Kim JB, Jung YJ, Hwang HY, Kim KH, Yoo JS, Lee S, Lee SH, Sung K, Je HG, Lim MH, Chang BC, Hong SC, Lee H, Shin YC, Kim JH, Lim C

Background: In this study, we present recent trends in heart valve surgery in Korea through analyses of data from the Korea Heart Valve Surgery Registry (KHVSR). Methods: We enrolled 8,981 patients...
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Long-Term Outcomes of Preoperative Atrial Fibrillation in Cardiac Surgery

Kim HH, Kim JH, Lee S, Joo HC, Youn YN, Yoo KJ, Lee SH

Background: Atrial fibrillation (Afib) is a marker of increased cardiovascular morbidity and mortality. Owing to the increased prevalence of Afib in patients undergoing cardiac surgery, assessing the effect of Afib...
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Feasibility of Deep Learning-Based Analysis of Auscultation for Screening Significant Stenosis of Native Arteriovenous Fistula for Hemodialysis Requiring Angioplasty

Park JH, Park I, Han K, Yoon J, Sim Y, Kim SJ, Won JY, Lee S, Kwon JH, Moon S, Kim GM, Kim Md

Objective: To investigate the feasibility of using a deep learning-based analysis of auscultation data to predict significant stenosis of arteriovenous fistulas (AVF) in patients undergoing hemodialysis requiring percutaneous transluminal angioplasty...
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Adenosine Deaminase 2 Deficiency Caused by Biallele Variants Including Splicing Variant: The First Case in Korea

Cho S, Park S, Lee JS, Ju YS, Choi YJ, Lee S

Deficiency of adenosine deaminase 2 (DADA2) is an autoinflammatory disease caused by pathogenic variants of the ADA2 gene and has similar clinical features to polyarteritis nodosa (PAN). We, herein, report...
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Long-Term Health Consequence of Discharged Patients with COVID-19: A Survey of Patients from Hospital Dedicated COVID-19 in 2021

Min J, Kim S, Choi J, Park H, Lee S, Cheung B, Park K

Background: Due to the prolonged coronavirus disease 2019 (COVID-19) pandemic, accumulating patients are experiencing long COVID symptoms. This study aimed to investigate whether COVID-19 sequelae affect individuals’ returns to daily...
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Generation and Application of Directly Reprogrammed Endothelial Cells

Jung C, Oh JE, Lee S, Yoon Ys

Cell-based therapy has emerged as a promising option for treating advanced ischemic cardiovascular disease by inducing vascular regeneration. However, clinical trials with adult cells turned out disappointing in general. As...
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Exploration of Potential Gut Microbiota-Derived Biomarkers to Predict the Success of Fecal Microbiota Transplantation in Ulcerative Colitis: A Prospective Cohort in Korea

Kang GU, Park S, Jung Y, Jee JJ, Kim MS, Lee S, Lee DW, Shin JH, Koh H

Background/Aims: Although fecal microbiota transplantation (FMT) has been proven as one of the promising treatments for patients with ulcerative colitis (UC), potential prognostic markers regarding the clinical outcomes of FMT...
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Treatment for relapsed acute promyelocytic leukemia: what is the best post-remission treatment?

Min GJ, Cho BS, Park SS, Park S, Jeon YW, Yahng SA, Shin SH, Yoon JH, Lee SE, Eom KS, Kim YJ, Lee S, Min CK, Cho SG, Lee JW, Kim HJ

Background Arsenic trioxide (ATO) is the standard treatment for relapsed acute promyelocytic leukemia (APL). However, consensus on post-remission therapies is still lacking. Methods We evaluated 52 patients who experienced relapse following initial treatment...
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Incomplete Intertrochanteric Fracture: A Pattern Analysis Using Multiplanar Reformation Computed Tomography

Kim HJ, Yoon JY, Lee S, Kim K, Yoo JJ

Background: Incomplete fractures are assumed to occur in the intertrochanteric area as fractures at other sites, but reports of incomplete intertrochanteric fractures (IIFs) are rare. In 1999, Schultz et al....
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Categorization of Potential Classes Using the University Counseling Center Service Application

Lee S, Lee K, Lee S, Lee Y, Kim M, Jung D

Objectives The purpose of this study was to classify the users of a university counseling center and define their characteristics using the information from the service application written by them...
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Treatment of Ankylosis of the Elbow Secondary to Failed Osteosynthesis of Intra-Articular Distal Humerus Fracture

Choi YJ, Lee S

A twenty-four-year-old patient presented with elbow ankylosis with a range of motion of 5° secondary to failed osteosynthesis 11 months after the internal fixation of an intra-articular distal humerus fracture....
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Comprehensive Rehabilitation in Severely Ill Inpatients With COVID-19: A Cohort Study in a Tertiary Hospital

Woo H, Lee S, Lee HS, Chae HJ, Jung J, Song MJ, Lim SY, Lee YJ, Cho YJ, Kim ES, Kim HB, Lim JY, Song KH, Beom J

Background: This study aimed to investigate the effects of comprehensive rehabilitation management on functional recovery and examine the correlation between clinical parameters and improvements in functional outcomes in severe-to-critical inpatients...
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Trends in Confirmed COVID-19 Cases in the Korean Military Before and After the Emergence of the Omicron Variant

Shin DH, Jang H, Lee S, Choi BS, Kim D, Oh HS

Background: Due to the higher transmissibility and increased immune escape of the omicron variant of severe acute respiratory syndrome coronavirus 2, the number of patients with coronavirus disease 2019 (COVID-19)...
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Operational Definition Identifying Osteoporotic Vertebral Fractures in the Claims Database

Yu MH, Hong N, Lee S, Kim HY, Park HS, Park SM, Lee YK, Kim TY, Ha YC, Rhee Y, Koo KH

Background: We analyzed the International Classification of Diseases, 10th edition (ICD-10) diagnostic codes, procedure codes, and radiographic image codes for vertebral fracture (VF) used in the database of Health Insurance...
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Evaluation of Intervention Policies for the COVID-19 Epidemic in the Seoul/Gyeonggi Region through a Model Simulation

Seok J, Lee Y, Choi JY, Choi Jp, Seo H, Lee S, Lee J

Purpose: To evaluate the efficacy of intervention policies on coronavirus disease-19 (COVID-19) dissemination. Materials and Methods: An age-structured compartmental model for the COVID-19 outbreak was proposed to predict the impact of...
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IntraBrain Injector (IBI): A StereotacticGuided Device for Repeated Delivery of Therapeutic Agents Into the Brain Parenchyma

Lee J, Lee S, Jung W, Kim GB, Kim T, Seong J, Jang H, Noh Y, Lee NK, Lee BR, Lee JI, Choi SJ, Oh W, Kim N, Lee S, Na DL

Background: To deliver therapeutics into the brain, it is imperative to overcome the issue of the blood-brain-barrier (BBB). One of the ways to circumvent the BBB is to administer therapeutics...
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Thyroglobulin‑Based Risk Factor Repositioning for Determining Radioactive Iodine Activity in Patients with Papillary Thyroid Carcinoma: a Multicenter Retrospective Cohort Study

Jeon S, Kwon S, Lee S, Bae S

Purpose We aimed to investigate the impact of various factors including radioactive iodine (RAI) activity on the therapeutic response according to the range of serum thyroglobulin (Tg) in patients with...
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Immunomodulatory Effect of Epidermal Growth Factor Secreted by Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells on Atopic Dermatitis

Jung N, Kong T, Yu Y, Park H, Lee E, Yoo S, Baek S, Lee S, Kang KS

Background and Objectives: Human mesenchymal stem cells (MSCs) are emerging as a treatment for atopic dermatitis (AD), a chronic inflammatory skin disorder that affects a large number of people across...
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Survival Outcomes and Predictors for Recurrence of Surgically Treated Brain Metastasis From Non-Small Cell Lung Cancer

Byun J, Kim JH, Kim M, Lee S, Kim YH, Hong CK, Kim JH

Background There are numerous factors to consider in deciding whether to undergo surgical treatment for brain metastasis from lung cancer. Herein, we aimed to analyze the survival outcome and predictors...
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Lower-Income Predicts Increased Smartphone Use and Problematic Behaviors Among Schoolchildren During COVID-19 Related School Modification: A Longitudinal Study

Her ES, Lee S, Yang SJ, Park L, Park MG, Kim SJ, Shin Y

Background: As the coronavirus disease 2019 (COVID-19) has continued for a couple of years, the long-term effects of the pandemic and the subsequent school curriculum modification on the mental health...
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