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Treatment of Periodontal Bone Defects with Stem Cells from Inflammatory Dental Pulp Tissues in Miniature Swine

Li Y, Nan X, Zhong TY, Li T, Li A

BACKGROUND: Containing a certain proportion of mesenchymal stem cells, inflammatory dental tissue showed great tissue regeneration potential in recent years. However, whether it is applicable to promote tissue regeneration in...
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Establishment and identification of cell lines from type O blood Korean native pigs and their efficiency in supporting embryonic development via somatic cell nuclear transfer

Taweechaipaisankul A, Kim GA, Jin JX, Yeom SC, Lee BC

Due to their similarities with humans in anatomy, physiology, and genetics miniature pigs are becoming an attractive model for biomedical research. We aim to establish and evaluate blood type O...
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Intrapancreatic ectopic splenic tissue found in a cloned miniature pig

Koo OJ, Ha SK, Park SJ, Park HJ, Kim SJ, Kwon D, Kang JT, Moon JH, Park EJ, Jang G, Lee BC

Somatic cell nuclear transfer (SCNT) is a cost-effective technique for producing transgenic pigs. However, abnormalities in the cloned pigs might prevent use these animals for clinical applications or disease modeling....
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Disagreement between direct and indirect blood pressure measurements obtained from minipigs

Lee WJ, Park LS

Blood pressure (BP) measurement plays a pivotal role in veterinary medicine for diagnosing cardiovascular disorders and monitoring anesthesia of animals. Although indirect BP measurement has been widely applied to monitor...
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Comparative analysis of heart functions in micropigs and conventional pigs using echocardiography and radiography

Lee MY, Lee SH, Lee SG, Park SH, Lee CY, Kim KH, Hwang SH, Lim SY, Ahn YK, Han HJ

The production of miniature animals has been suggested for use in organ transplantation. At present, many of the studies about application of animal organs to human have been focused on...
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Laparoscopic left hepatectomy in swine: a safe and feasible technique

Zhang H, Liu T, Wang Y, Liu HF, Zhang JT, Wu YS, Lei L, Wang HB

A purely laparoscopic four-port approach was created for left hepatectomy in pigs. A polyethylene loop was placed on the left two hepatic lobes for traction and lift. Next, penetrating ligation...
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Effectiveness of autogenous tooth bone used as a graft material for regeneration of bone in miniature pig

Jeong HR, Hwang JH, Lee JK

  • KMID: 2328610
  • J Korean Assoc Oral Maxillofac Surg.
  • 2011 Oct;37(5):375-379.
INTRODUCTION: This study examined the effect of autogenous tooth bone used as a graft material for bone regeneration in an artificial bony defect of minipigs. MATERIALS AND METHODS: Four healthy minipigs,...
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Development of osteoporosis animal model using micropigs

Kim SW, Kim KS, Solis CD, Lee MS, Hyun BH

  • KMID: 2312111
  • Lab Anim Res.
  • 2013 Sep;29(3):174-177.
Osteoporosis is a known major health problem and a serious disease of the bone, there has been a great need to develop more and newer animal models for this disease....
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Spectral Doppler ultrasound in the major arteries of normal conscious immature micropigs

Jung J, Chang J, Oh S, Choi M

Spectral waveform analysis of blood flow velocity in the major arteries of six healthy, conscious immature micropigs was determined using Doppler ultrasonography. Doppler spectral tracings were recorded from the external...
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Porcine study on the efficacy of autogenous tooth bone in the maxillary sinus

Lee DH, Yang KY, Lee JK

OBJECTIVES: This study sought to elucidate the effect of autogenous tooth bone material by experimenting on minipig's maxillary sinus and performing histological and histomorphometric analyses. MATERIALS AND METHODS: Five 18-24 month-old...
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Evaluation of Optimal Stent Size after Endourologic Incision of Ureteral Strictures

Moon YT, Clayman RV

  • KMID: 2060559
  • Korean J Urol.
  • 1995 Jan;36(1):75-82.
All endoureteromy procedures have in common the use of a ureteral stent as post-procedure However, the optimal stent size necessary to promote satisfactory healing is not known. Herein we compared...
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Magnetic resonance imaging evaluation of Yukatan minipig brains for neurotherapy applications

Yun SP, Kim DH, Ryu JM, Park JH, Park SS, Jeon JH, Seo BN, Kim HJ, Park JG, Cho KO, Han HJ

Magnetic resonance imaging (MRI) of six Yukatan minipig brains was performed. The animals were placed in stereotaxic conditions currently used in experiments. To allow for correctpositioning of the animal in...
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Effectiveness of 99mTc-tetrofosmin for assessment of heart functions in micropigs

Lee MY, Lee SH, Park JH, Heo JS, Lee YJ, Suh HN, Min JJ, Seo YS, Han HJ

This study examined the suitability of a nuclear imagingtechnique using 99mTc-tetrofosmin as an agent to assess theheart functions of healthy micropigs. The mean age of thepigs was 360 days (male),...
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The Performance of Multiple Transgastric Procedures Using the Natural Orifice Transluminal Endoscopic Surgery Technique: Is Pure NOTES Satisfactory?

Song TJ, Seo DW, Kim SH, Park DH, Lee SS, Lee SK, Kim MH

  • KMID: 2167416
  • Gut Liver.
  • 2012 Oct;6(4):457-463.
BACKGROUND/AIMS: Although several groups have demonstrated the usefulness of natural orifice transluminal endoscopic surgery (NOTES), there is still concern about frequent serious adverse events. We performed this study to determine...
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Contrast-enhanced ultrasound analysis of renal perfusion in normal micropigs

Yi K, Ji S, Kim J, Yoon J, Choi M

Contrast-enhanced ultrasound is one of method for evaluating renal perfusion. The purpose of this project was to assess perfusion patterns and dynamics in normal micropig kidney using ultrasonographic contrast media....
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Benefits of procyanidins on gut microbiota in Bama minipigs and implications in replacing antibiotics

Zhao T, Shen X, Dai C, Cui L

Several studies have reported the effect of absorption of procyanidins and their contribution to the small intestine. However, differences between dietary interventions of procyanidins and interventions via antibiotic feeding in...
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Computed tomographic evaluation of abdominal fat in minipigs

Chang J, Jung J, Lee H, Chang D, Yoon J, Choi M

Computed tomography (CT) exams were conducted to determine the distribution of abdominal fat identified based on the CT number measured in Hounsfield Units (HU) and to measure the volume of...
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64-Channel multi-detector row CT angiographic evaluation of the micropigs for potential living donor lung transplantation

Yoon W, Ryu JM, Lee MY, Moon YJ, Lee SH, Park JH, Yun SP, Jang MW, Park SS, Han HJ

Micropigs are the most likely source animals for xenotransplantation. However, an appropriate method for evaluating the lung of micropigs had not been established. Therefore, this study was performed to evaluate...
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Differential regulation of senescence and in vitro differentiation by 17β-estradiol between mesenchymal stem cells derived from male and female mini-pigs

Lee WJ, Lee SC, Lee JH, Rho GJ, Lee SL

The characterization and potential of mesenchymal stem cells (MSCs) are gender dependent and estrogen influences these properties. This study demonstrated that supplementation with 17β-estradiol (E2) increases the proliferation of bone...
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Multidetector computed tomographic angiography evaluation of micropig major systemic vessels for xenotransplantation

Ryu JM, Yoon W, Park JH, Yun SP, Jang MW, Han HJ

Due primarily to the increasing shortage of allogeneic donor organs, xenotransplantation has become the focus of a growing field of research. Currently, micropigs are the most suitable donor animal for...
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