Korean J Dermatol.  2012 Sep;50(9):788-794.

Isolation of the Causative Microorganism and Antimicrobial Susceptibility of Impetigo

• Kim WJ
• Lee KR
• Lee SE
• Lee HJ
• Yoon MS

Abstract

BACKGROUND
Impetigo is a common bacterial infection caused by Staphylococcus aureus, and group A beta-hemolytic Streptococcus or both. Recently, S. aureus has been reported as the most frequently isolated pathogen of impetigo and the incidence of methicillin-resistant S. aureus (MRSA) among patients with impetigo has increased.
OBJECTIVE
To investigate the predominant microorganism and the antibiotic susceptibility of the impetigo causative pathogen.
METHODS
Bacterial culture and antimicrobial susceptibility testing were performed in patients with impetigo from June 2006 to May 2012.
RESULTS
Of 164 patients, bacteria were cultured from 139 patients. Among them, S. aureus was isolated from 114 (82%) patients. The others were Acinetobacter baumannii, Enterobactercloacae, Enterococcus species, Enterococcus faecium, Enterococcus faecalis, Klebsiella oxytoca, and Candida albicans. The resistance rates of S. aureus against antibiotics were as follows: penicillin, 95.6%; erythromycin, 43.9%; fusidicacid, 38.1%; clindamycin, 24.5%; gentamycin, 21%; tetracycline, 12.3%; trimethoprim-sulfamethoxazole, 0.9%; ciprofloxacin, 0%; habekacin, 0%; linezolid, 0%; teicoplanin, 0%; and vancomycin, 0%. Thirty-four (29.8%) S. aureus isolates were MRSA, and the prevalence of MRSA increased during the 6-year period.
CONCLUSION
The most predominant pathogen in impetigo was S. aureus, which was sensitive to ciprofloxacin, habekacin, linezolid, trimethoprim-sulfamethoxazole, teicoplanin, and vancomycin. An increase in the prevalence of MRSA was observed during the 6-year period, and the effective antibiotics for MRSA were trimethoprim-sulfamethoxazole, teicoplanin and vancomycin.

Keyword

Antibiotics susceptibility; Impetigo; MRSA; Staphylococcus aureus

MeSH Terms

Acetamides
Acinetobacter baumannii
Anti-Bacterial Agents
Bacteria
Bacterial Infections
Candida albicans
Ciprofloxacin
Clindamycin
Dibekacin
Enterococcus
Enterococcus faecalis
Enterococcus faecium
Erythromycin
Gentamicins
Humans
Impetigo
Incidence
Klebsiella oxytoca
Methicillin Resistance
Methicillin-Resistant Staphylococcus aureus
Oxazolidinones
Penicillins
Prevalence
Staphylococcus aureus
Streptococcus
Teicoplanin
Tetracycline
Trimethoprim, Sulfamethoxazole Drug Combination
Vancomycin
Linezolid
Acetamides
Anti-Bacterial Agents
Ciprofloxacin
Clindamycin
Dibekacin
Erythromycin
Gentamicins
Oxazolidinones
Penicillins
Teicoplanin
Tetracycline
Trimethoprim-Sulfamethoxazole Combination
Vancomycin