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Role of Efflux Pump Gene adeIJK to Multidrug Resistance in Acinetobacter baumannii Clinical Isolates

Choi JA, Kim CM, Jang SJ, Cho SS, Jang CH, Ko YJ, Kang SH, Park G

BACKGROUND: The emergence of multidrug-resistant Acinetobacter baumannii as a nosocomial pathogen is one of the major public health problems. The aim of this study was to evaluate the role of...
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Antimicrobial Susceptibility of Microorganisms Isolated from Patients with Intraabdominal Infection in Korea: a Multicenter Study

Yoon YK, Kim J, Moon C, Lee MS, Hur J, Lee H, Kim SW

BACKGROUND: This study evaluated the antimicrobial susceptibility of pathogens isolated from Korean patients with intraabdominal infections (IAIs). METHODS: This multicenter study was conducted at 6 university-affiliated hospitals in Korea between 2016...
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Serotyping and Antimicrobial Susceptibility of Salmonella Isolated in Korea in 2015

Kim SH, Park EH, Hwang IY, Lee H, Song SA, Lee M, Lee S, Kim SY, Kim JJ, Shin JH, Hong SG, Shin KS, Kim S, Ryoo NH, Lee W, Jang SJ, Shin JH

BACKGROUND: Salmonella is an important pathogen that causes gastroenteritis and sepsis in humans. Recently, changes in serotype prevalence and an increase in antimicrobial resistance have been reported. This study investigated...
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Management of Typhoid Fever – Clinical and Historical Perspectives in Korea

Chang MS, Woo JH, Kim S

Typhoid fever, showed a dramatic decrease in its incidence from 56 per 100,000 population just after Korea's independence to
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Two Manganese Peroxidases and a Laccase of Trametes polyzona KU-RNW027 with Novel Properties for Dye and Pharmaceutical Product Degradation in Redox Mediator-Free System

Lueangjaroenkit P, Teerapatsakul C, Sakka K, Sakka M, Kimura T, Kunitake E, Chitradon

Two manganese peroxidases (MnPs), MnP1 and MnP2, and a laccase, Lac1, were purified from Trametes polyzona KU-RNW027. Both MnPs showed high stability in organic solvents which triggered their activities. Metal...
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Comparison of Escherichia coli and Klebsiella pneumoniae Acute Pyelonephritis in Korean Patients

Hyun M, Lee JY, Kim HA, Ryu SY

BACKGROUND: Escherichia coli and Klebsiella pneumoniae are two of the most common causes of urinary tract infection. The purpose of this study was to compare clinical characteristics and antimicrobial susceptibility...
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Antimicrobial Susceptibility and Genetic Analysis of Campylobacter jejuni Isolated from Diarrhea Patients in Busan

Park SH, Kim BJ, Kwon YH, Hwang IY, Sung GH, Park EH, Jin SH

BACKGROUND: Campylobacter jejuni is an important food-borne pathogen that causes human gastroenteritis. This study was conducted to investigate the incidence of isolation, antimicrobial susceptibility pattern, and C. jejuni genotype from...
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Multiplex PCR analysis of virulence genes and their influence on antibiotic resistance in Enterococcus spp. isolated from broiler chicken

Song H, Bae Y, Jeon E, Kwon Y, Joh S

Enterococcus spp. are opportunistic pathogens that cause lameness in broiler chickens, resulting in serious economic losses worldwide. Virulence of Enterococcus spp. is associated with several putative virulence genes including fsr,...
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Positive culture rate and antimicrobial susceptibilities of Mycoplasma hominis and Ureaplasma urealyticum

Jang YS, Min JW, Kim YS

OBJECTIVE: To assess positive culture rate and antimicrobial susceptibilities of Mycoplasma hominis (MH) and Ureaplasma urealyticum (UU) in symptomatic general population and pregnant women admitted with preterm labor and premature...
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Antimicrobial resistance profiles of vancomycin-resistant Enterococcus species isolated from laboratory mice

Yamanaka H, Kadomatsu , Takagi T, Ohsawa M, Yamamoto N, Kubo N, Takemoto T, Ohsawa K

Isolates of 24 enterococci, 5 Enterococcus casseliflavus and 19 Enterococcus gallinarum, possessing vanC genes and showing low-level resistance to vancomycin were obtained from mice from commercial mouse breeding companies. Since...
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Clinical Characteristics and Antimicrobial Susceptibility Trends in Citrobacter Bacteremia: An 11-Year Single-Center Experience

Lee R, Choi SM, Jo SJ, Lee J, Cho SY, Kim SH, Lee DG, Jeong HS

BACKGROUND: Recently, Citrobacter freundii bacteremia outbreak in a neonatal intensive care unit has attracted public attention in Korea. However, Citrobacter bacteremia is uncommon and usually occurs in patients with underlying...
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Microbiome diversity in carriers of fluoroquinolone resistant Escherichia coli

Liss MA, Leach RJ, Rourke E, Sherrill A, Johnson-Pais T, Lai Z, Basler J, White JR, Patterson

PURPOSE: Fluoroquinolone-resistant (FQR) Escherichia coli causes transrectal prostate biopsy infections. In order to reduce colonization of these bacteria in carriers, we would like to understand the surrounding microbiome to determine...
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Treatment Strategy and Outcomes in Patients with Hematogenous Culture-Negative Pyogenic Vertebral Osteomyelitis

Mohamad G, Amritanand R, David KS, Krishnan V, Arockiaraj J

STUDY DESIGN: Retrospective case series. PURPOSE: The aim of this study was to analyze functional and radiological outcomes in patients with culture-negative pyogenic vertebral osteomyelitis (PVO). OVERVIEW OF LITERATURE: There were only...
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Evaluation of in vitro antimicrobial susceptibility of Bacillus anthracis strains isolated during anthrax outbreaks in Italy from 1984 to 2017

Manzulli V, Fasanella , Parisi A, Serrecchia L, Donatiello A, Rondinone , Caruso M, Zange S, Tscherne A, Decaro N, Pedarra C, Galante D

Anthrax, caused by Bacillus anthracis, is a non-contagious infectious disease that affects a wide range of animal species (primarily ruminants) including humans. Due to the often-fatal outcome in humans, quick...
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Comparing infective complications from transrectal ultrasound guided prostate biopsy following transition to single dose oral ciprofloxacin prophylaxis

Farag M, Riddell S, Daffy J, Wong LM

PURPOSE: To examine the incidence of infective complications post Transrectal Ultrasound Guided Prostate Biopsy (TRUSPB), after transition to preoperative administration of single dose oral ciprofloxacin. MATERIALS AND METHODS: A retrospective study...
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Optimal Modified Extended Antibiotic Prophylaxis for Prostate Biopsy: The Addition of Two Intravenous Doses of Amikacin to Ciprofloxacin

Yu SH, Jung SI, Kim MS, Chung HS, Kwon DD

PURPOSE: This retrospective study was undertaken to investigate whether increasing amikacin dosage for ciprofloxacin prophylaxis in patients with fluoroquinolone (FQ)-resistant rectal flora reduce infectious complications after transrectal ultrasound-guided prostate biopsy...
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Failure of Ciprofloxacin Therapy in the Treatment of Community-Acquired Acute Pyelonephritis caused by In-Vitro Susceptible Escherichia coli Strain Producing CTX-Type Extended-Spectrum β-Lactamase

Seok H, Cha MK, Kang CI, Cho SY, Kim SH, Ha YE, Chung DR, Peck KR, Song JH

While carbapenems are the drug of choice to treat extended-spectrum-β-lactamase (ESBL)-producing strains, some alternative carbapenem-sparing regimens are suggested for antibiotic stewardship. We experienced a case of ciprofloxacin treatment failure for...
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Effect of Intracanal Medicaments on Push-out Bond Strength of Calcium Silicate-based Materials

Jeong H, Yang S, Kim S, Choi N, Kim J

The purpose of this study was to evaluate the effect of the intracanal medicaments on the push-out bond strength of the calcium silicate-based materials. Forty extracted single-root human mandibular premolars were...
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Combination of berberine and ciprofloxacin reduces multi-resistant Salmonella strain biofilm formation by depressing mRNA expressions of luxS, rpoE, and ompR

Shi C, Li M, Muhammad I, Ma X, Chang Y, Li R, Li C, He J, Liu F

Bacterial biofilms have been demonstrated to be closely related to clinical infections and contribute to drug resistance. Berberine, which is the main component of Coptis chinensis, has been reported to...
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Concurrent Use of Sulfonylureas and Antimicrobials of the Elderly in Korea: A Potential Risk of Hypoglycemia

Lee S, Ock M, Kim H

BACKGROUND: Previous studies have noted that the simultaneous use of sulfonylureas and antimicrobials, which is common, could increase the risk of hypoglycemia. In particular, an age of 65 years or...
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