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Multiple Abscesses Following COVID-19 Vaccination: A Case Report

Lee H, Kim GL, Kim T

Vaccines can cause adverse reactions, such as soreness, swelling, or redness at the injection site. Some reactions are associated with fever and rash, which are usually mild and transient, and...
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Feasibility of Using Bacteriophage Therapy to Reduce Morbidity and Mortality Associated with Spinal Epidural Abscesses

Doub JB, Tran J, Smith R, Pease T, Koh E, Ludwig S, Lee A, Chan B

Background: The aim of this study was to determine the feasibility of using bacteriophage therapeutics in spinal epidural abscess (SEA) by reviewing the causes and outcomes of SEA at a...
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Anti-Alpha-Toxin Antibody Responses and Clinical Outcomes of Staphylococcus aureus Bacteremia

Kim NH, Choi Y, Kwon K, Park JS, Park KU, Moon SM, Song KH, Kim ES, Park WB, Kim HB

Background: Alpha-toxin (AT), a major virulence factor of Staphylococcus aureus, is an important immunotherapeutic target to prevent or treat invasive S. aureus infections. Previous studies have suggested that anti-AT antibodies...
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Bioprospecting of Endophytic Fungi as Promising Anti-MRSA Agents

Wei YM, Tan JS, Tang HW, Tong WY, Leong CR, Tan WN

Methicillin-resistant Staphylococcus aureus (MRSA) is a serious threat to the global healthcare system. Ineffective and resistance to antibiotic treatments have increased morbidity and mortality rates worldwide. New and effective antibiotics are...
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Antibacterial activity of florfenicol composite nanogels against Staphylococcus aureus small colony variants

Liu J, Ju M, Wu Y, Leng N, Algharib SA, Luo W

Background: Florfenicol might be ineffective for treating Staphylococcus aureus small colony variants (SCVs) mastitis. Objectives: In this study, florfenicol-loaded chitosan (CS)-sodium tripolyphosphate (TPP) composite nanogels were prepared to allow targeted...
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Feasibility of Loop-Mediated Isothermal Amplification for Rapid Detection of Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus in Tissue Samples

Kim SG, Choi GW, Choi WS, Lim CS, Jang WS, Bae JH

Background: To date, few studies have investigated the feasibility of the loop-mediated isothermal amplification (LAMP) assay for identifying pathogens in tissue samples. This study aimed to investigate the feasibility of...
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Antibiotics for multidrug-resistant gram-positive bacteria

Song KH

Background: Antimicrobial resistance is a major global threat to public health and is associated with increased morbidity and mortality. A few therapeutic options for the treatment of multidrug resistant (MDR)...
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Adipose-derived stem cells decolonize skin Staphylococcus aureus by enhancing phagocytic activity of peripheral blood mononuclear cells in the atopic rats

Lee J, Park L, Kim H, Rho Bi, Han RT, Kim S, Kim HJ, Na HS, Back SK

Staphylococcus aureus (S. aureus ) is known to induce apoptosis of host immune cells and impair phagocytic clearance, thereby being pivotal in the pathogenesis of atopic dermatitis (AD). Adipose-derived stem...
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Comparison of Clinical Outcomes for Glycopeptides and Beta-Lactams in Methicillin-Susceptible Staphylococcus Aureus Bloodstream Infections

La YJ, Kim HR, Oh DH, Ahn JY, Kim YC

Purpose: This study aimed to provide compelling evidence of anti-staphylococcal beta-lactam use for methicillin-susceptible Staphylococcus aureus bloodstream infection (MSSA BSI). Materials and Methods: We retrospectively collected data on patients with MSSA...
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Effects of Stepwise Application of Active Surveillance Culture, Preemptive Isolation, and Chlorhexidine Bed Bath on the Acquisition of Methicillin-resistant Staphylococcus aureus in Children Undergoing Cardiac Surgery in the Paediatric Intensive Care Unit

Cho SY, Jeong JS, Kim EO, Kim YH

Background: This study aimed to investigate the effects of stepwise strengthening of methicillinresistant Staphylococcus aureus (MRSA) infection control on the acquisition and identification of risk factors for acquiring MRSA in...
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Scalp Reconstruction and Cranioplasty using the Latissimus Dorsi Musculocutaneous Flap in a Patient with Recurrent Wound Dehiscence Accompanied by MRSA Infection

Yoon T, Kim SW

The latissimus dorsi flap has high vascularity and is helpful for the reconstruction of infected areas. Herein, we present a patient with recurrent infections and soft-tissue defects who underwent cranial...
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Antibacterial activity of enrofloxacin loaded gelatin-sodium alginate composite nanogels against intracellular Staphylococcus aureus small colony variants

Luo W, Liu J, Algharib SA, Chen W

Background: The poor intracellular concentration of enrofloxacin might lead to treatment failure of cow mastitis caused by Staphylococcus aureus small colony variants (SASCVs). Objectives: In this study, enrofloxacin composite nanogels were...
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Urgent need for novel antibiotics in Republic of Korea to combat multidrug-resistant bacteria

Lee HJ, Lee DG

Multidrug resistance in bacteria is an important issue and is increasing in frequency worldwide because of the limitations of therapeutic agents. From 2010 to 2019, 14 new systemic antibiotics received...
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Clinical Efficacy and Safety of Arbekacin against Pneumonia in Febrile Neutropenia: A Retrospective Study in Patients with Hematologic Malignancies

Ohashi T, Fujita Y, Irisawa H, Nakaminami H, Arai T, Takahashi M, Momiyama E, Murata N, Murayama K, Saito T

Background: Arbekacin (ABK) is an aminoglycoside that exhibits anti-methicillin-resistant Staphylococcus aureus (MRSA) and anti-Pseudomonas aeruginosa activities. Therefore, for patients with febrile neutropenia (FN) and concurrent pneumonia suspected to be caused...
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Enhanced antibacterial activity of tilmicosin against Staphylococcus aureus small colony variants by chitosan oligosaccharide-sodium carboxymethyl cellulose composite nanogels

Luo W, Liu J, Zhang S, Song W, Algharib SA, Chen W

Background: The poor bioadhesion capacity of tilmicosin resulting in treatment failure for Staphylococcus aureus small colony variants (SASCVs) mastitis. Objectives: This study aimed to increase the bioadhesion capacity of tilmicosin for...
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Central Skull Base Osteomyelitis Presenting with Bilateral Abducens Nerve Palsy

Park J, Ko E, Hwang E, Na S

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Nasal Colonization of Serine Protease esp Positive Staphylococcus epidermidis Affecting Staphylococcus aureus Colonization

Kang G, Kim HS, Kim HS, Song W, Kim JS

Background: Staphylococcus aureus is a common colonizer of the nasal vestibule and is found in approximately 20%–30% of healthy adults, while Staphylococcus epidermidis appears to be the most frequent colonizer...
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Evaluation of copper alloys for reducing infection by methicillin resistant Staphylococcus aureus and vancomycin resistant Enterococcus faecium in intensive care unit and in vitro

Choi SI, Chang MS, Kim T, Chung KH, Bae S, Kim SH, Yoon CJ, Kim YK, Woo JH

Background/Aims: Multi-drug resistant pathogens are increasing among healthcare-associated infections. It is well known that copper and copper alloys have antimicrobial activity. We evaluated the activity of copper against bacteria in...
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A Case of Methicillin-Sensitive Staphylococcus aureus Bacteremia Superimposed on Eczema Herpeticum in a Patient with Uncontrolled Atopic Dermatitis

Lee YS, Kim YS, Lee JH, Choi JE, Han TY

  • KMID: 2518995
  • Korean J Dermatol.
  • 2021 Jul;59(6):491-494.
Eczema herpeticum is a widespread herpes simplex infection that favors eczema-damaged skin, including skin involved with atopic dermatitis. Here we report a case of a 27-year-old woman who presented with...
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Ten-Year Prevalence Trends of Phenotypically Identified Community-Associated Methicillin-Resistant Staphylococcus aureus Strains in Clinical Specimens

Yu SH, Lee JH, Kim MC, Choi SH, Chung JW, Lee MK

Background: Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) strains were first detected in hospitals in Korea between the late 2000s and early 2010s. However, there is limited information regarding the prevalence of CA-MRSA...
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