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Development and validation of a comorbidity index for predicting survival outcomes after allogeneic stem cell transplantation in adult patients with acute leukemia: a Korean nationwide cohort study

Park SS, Kim HJ, Kim TY, Lee Jy, Lee JH, Min GJ, Park S, Yoon JH, Lee SE, Cho BS, Eom KS, Kim YJ, Lee S, Kim DW

Background Allogeneic hematopoietic stem cell transplantation (alloSCT) is a potentially curative treatment option for acute leukemia. We aimed to identify the comorbidity factors affecting survival outcomes after alloSCT and develop a...
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Pancreatic Collision Tumor of Desmoid-Type Fibromatosis and Mucinous Cystic Neoplasm: A Case Report

Ryu MJ, Kim JW, Lee SE, Choi JH

Pancreatic collision tumors are rare neoplasm, and cases consisting of ductal adenocarcinoma with a neuroendocrine tumor, intraductal papillary mucinous neoplasm with a neuroendocrine tumor, and solid pseudopapillary neoplasm with a...
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Region-Specific Differences in the Apoe4-dependent Response to Focal Brain Injury

Lee SE, Yang H, Sung Y, Kim Y, Park SA

  • KMID: 2519890
  • Exp Neurobiol.
  • 2021 Aug;30(4):285-293.
  • doi: 10.5607/en21022
Apolipoprotein E (apoE) plays a role in various physiological functions including lipid transport, synaptic plasticity, and immune modulation. Epidemiological studies suggest that the apoE4 allele increases the risk of post-traumatic sequelae....
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Significant Domains of Life Satisfaction That Affect Suicidal Behavior in Adolescents

Kim JS, Choi SH, Lee SE, Lee CW, Kim WH, Bae JN, Lee JS, Maeng S, Son J, Kim H

  • KMID: 2516959
  • J Korean Acad Child Adolesc Psychiatry.
  • 2021 Jul;32(3):104-111.
  • doi: 10.5765/jkacap.210004
Objectives: Adolescent suicide is a serious national issue in Korea. Recently, life satisfaction has been recognized as a major factor related to this issue. The main purpose of this study...
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Sound Processor Replacement in Patients with Cochlear Implant: Analysis of a 30-Year Single-Institutional Experience

Lee MJ, Lee SE, Mun JY, Lee KY

Background and Objectives The purpose of this study is to investigate the replacement of external sound processors and to help understand the economic burden experienced from cochlear implant users. Subjects and...
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Development and Validation of a Deep Learning Based Diabetes Prediction System Using a Nationwide Population-Based Cohort

Rhee SY, Sung JM, Kim S, Cho IJ, Lee SE, Chang HJ

Background: Previously developed prediction models for type 2 diabetes mellitus (T2DM) have limited performance. We developed a deep learning (DL) based model using a cohort representative of the Korean population. Methods:...
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Efficacy of sentinel lymph node biopsy with radioisotope alone and the prediction of sentinel node status using PET-CT in breast cancer

Song R, Kwon SU, Yoon DS, Bae IE, Choi IS, Choi WJ, Lee SE, Moon JI, Sung NS, Lee SJ, Roh SJ, Kim SG

Purpose: Sentinel lymph node biopsy (SLNB) using both a radioactive isotope (RI) and blue dye is considered highly effective; however, there were limitations with the use of both agents in...
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Differential Cellular Tropism of Lentivirus and Adeno-Associated Virus in the Brain of Cynomolgus Monkey

An H, Cho DW, Lee SE, Yang YS, Han SC, Lee CJ

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Expression of LONP1 Is High in Visceral Adipose Tissue in Obesity, and Is Associated with Glucose and Lipid Metabolism

Lee JH, Jung SB, Lee SE, Kim JE, Kim JT, Kang YE, Kang SG, Yi HS, Ko YB, Lee KH, Ku BJ, Shong M, Kim HJ

Background: The nature and role of the mitochondrial stress response in adipose tissue in relation to obesity are not yet known. To determine whether the mitochondrial unfolded protein response (UPRmt)...
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Disease modifying agents of myeloproliferative neoplasms: a review

Lee SE

The identification of driver mutations in Janus kinase (JAK ) 2, calreticulin (CALR), and myeloproliferative leukemia (MPL) has contributed to a better understanding of disease pathogenesis by highlighting the importance...
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Early Safety Monitoring of COVID-19 Vaccines in Healthcare Workers

Song JY, Cheong HJ, Kim SR, Lee SE, Kim SH, Noh JY, Yoon YK, Choi WS, Park DW, Sohn JW, Kim WJ, Kim MJ

Hospital-based surveillance for adverse events was conducted on healthcare workers after they received the first dose of coronavirus disease 2019 (COVID-19) vaccine. Among the two new platform vaccines (messenger RNA-...
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Adenocarcinoma of the minor salivary gland with concurrent MAML2 and EWSR1 alterations

Choi S, Cho J, Lee SE, Baek CH, Kim YK, Kim HJ, Ko YH

Salivary gland tumors are histologically diverse, and each entity has distinctive histopathological and molecular features. We report two cases of salivary gland tumors with unique histological and molecular findings, which...
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Mechanisms of Resorcinol Antagonism of Benzo[a]pyrene-Induced Damage to Human Keratinocytes

Lee SE, Kwon K, Oh SW, Park SJ, Yu E, Kim H, Yang S, Park JY, Chung WJ, Cho JY, Lee J

Benzo[a]pyrene (B[a]P) is a polycyclic aromatic hydrocarbon and ubiquitous environmental toxin with known harmful effects to human health. Abnormal phenotypes of keratinocytes are closely associated with their exposure to B[a]P....
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Insulin Resistance Increases Serum Immunoglobulin E Sensitization in Premenopausal Women

Lee SE, Baek JY, Han K, Koh EH

Background Although studies have shown that obesity is associated with aeroallergen sensitization (atopy), controversy still exists. We aimed to investigate the association between metabolic status, obesity, and atopy stratified by sex...
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The clinical, laboratory, and radiologic improvement due to siltuximab treatment in idiopathic multicentric Castleman’s disease

Min GJ, Jeon YW, Park SS, Park S, Shin SH, Yahng SA, Yoon JH, Lee SE, Cho BS, Eom KS, Kim YJ, Lee S, Kim HJ, Min CK, Kim DW, Lee JW, Cho SG

Background/Aims: Idiopathic multicentric Castleman disease (iMCD) comprises approximately 30% of all cases of Castleman disease. It is characterized by constitutional symptoms, enlarged lymph nodes at multiple anatomical sites, and laboratory...
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A Survey on the Public Perceptions of Disaster-Related Mental Health Service

Lee SE, Lee N, Yoo S, Park D, Jeon K, Hwang TY, Lee JH

Objectives This study examined post-disaster mental health problems and related public perception of disaster-related mental health services. The differences of these perceptions according to the disaster experience and disaster type...
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Bone Generation Following Repeated Administration of Recombinant Bone Morphogenetic Protein 2

Son HJ, Lee MN, Kim Y, Choi H, Jeong BC, Oh SH, Kim JW, Kwon SH, Kim SH, Song SC, Lee SE, Koh JT

BACKGROUND: The delivery of recombinant human bone morphogenetic protein 2 (rhBMP2) by using various carriers has been used to successfully induce bone formation in many animal models. However, the effect...
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Extraskeletal Ewing Sarcoma of the Chest Wall Manifesting as a Palpable Breast Mass: Ultrasonography, CT, and MRI Findings

Kim M, Lee SE, Choi JH

Ewing sarcomas constitute a group of small, round, blue cell tumors of the bone and soft tissue. Extraskeletal Ewing sarcoma (EES) is a rare malignant neoplasm that arises from soft...
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Rationale and Study Design of the Withdrawal of Spironolactone for Heart Failure with Improved Left Ventricular Ejection Fraction

Hyun J, Lee SE, Lee SA, Hong JA, Kim MS, Kim JJ

It is unclear if guideline-directed medical therapy (GDMT) should be maintained in patients who have heart failure (HF) with improved ejection fraction (HFiEF). Of the medications recommended for HF, mineralocorticoid...
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Induced neural stem cells from human patient-derived fibroblasts attenuate neurodegeneration in Niemann-Pick type C mice

Hong S, Lee SE, Kang I, Yang J, Kim H, Kim J, Kang KS

Background: Niemann-Pick disease type C (NPC) is caused by the mutation of NPC genes, which leads to the abnormal accumulation of unesterified cholesterol and glycolipids in lysosomes. This autosomal recessive...
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