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Clindamycin-doxycycline-metronidazole combination therapy in a refractory canine babesiosis case

An HM, Song JH, An SJ, Yu DH, Han D, Kim YJ, Jung DI

An 8-year-old castrated male Maltese dog (patient) was referred to our institute with refractory canine babesiosis. The patient had previously responded to conventional treatment with atovaquone and azithromycin; however, anemia...
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The First Case of Otitis in Korea Caused by Brevibacterium otitidis

Mun SH, Lee AJ, Kim SG, Jeon CH, Park CG, Suh HS

Brevibacterium spp. are gram-positive rods that are considered to be strictly nonpathogenic, and a very few cases of their infection in humans have been reported. In this study, we report...
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Antimicrobial Susceptibility Patterns of Anaerobic Bacterial Clinical Isolates From 2014 to 2016, Including Recently Named or Renamed Species

Byun JH, Kim M, Lee Y, Lee K, Chong Y

BACKGROUND: Anaerobic bacterial resistance trends may vary across regions or institutions. Regional susceptibility patterns are pivotal in the empirical treatment of anaerobic infections. We determined the antimicrobial resistance patterns of...
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Analysis of Resistance to Macrolide–Lincosamide–Streptogramin B Among mecA-Positive Staphylococcus Aureus Isolates

Khodabandeh M, Mohammadi , Abdolsalehi MR, Alvandimanesh A, Gholami M, Bibalan MH, Pournajaf , Kafshgari , Rajabnia R

OBJECTIVES: Genetic determinants conferring resistance to macrolide, lincosamide, and streptogramin B (MLSB) via ribosomal modification such as, erm, msrA/B and ereA/B genes are distributed in bacteria. The main goals of...
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Evaluation of in vitro antimicrobial susceptibility of Bacillus anthracis strains isolated during anthrax outbreaks in Italy from 1984 to 2017

Manzulli V, Fasanella , Parisi A, Serrecchia L, Donatiello A, Rondinone , Caruso M, Zange S, Tscherne A, Decaro N, Pedarra C, Galante D

Anthrax, caused by Bacillus anthracis, is a non-contagious infectious disease that affects a wide range of animal species (primarily ruminants) including humans. Due to the often-fatal outcome in humans, quick...
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Revitalization of necrotic mature permanent incisors with apical periodontitis: a case report

Nagas E, Uyanik MO, Cehreli ZC

Despite considerable focus on the regenerative endodontic treatment of immature teeth with necrotic infected pulps and apical periodontitis, little data exist with regard to its possible implementation in necrotic permanent...
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Antibiotic resistance of Staphylococcus aureus colonized in children with staphylococcal scalded skin syndrome

Kong SG

OBJECTIVES: Systemic antibiotic therapy with semisynthetic penicillinase-resistant penicillin or vancomycin and clindamycin are recommended for the treatment of staphylococcal scalded skin syndrome (SSSS). This study assessed the rate of antibiotic...
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Prevalence, toxin gene profile, antibiotic resistance, and molecular characterization of Clostridium perfringens from diarrheic and non-diarrheic dogs in Korea

Chon JW, Seo KH, Bae D, Park JH, Khan S, Sung K

Clostridium perfringens causes diarrhea and other diseases in animals and humans. We investigated the prevalence, toxin gene profiles, and antibiotic resistance of C. perfringens isolated from diarrheic dogs (DD) and...
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Molecular Epidemiological Features and Antibiotic Susceptibility Patterns of Streptococcus dysgalactiae subsp. equisimilis Isolates from Korea and Japan

Kim S, Byun JH, Park H, Lee J, Lee HS, Yoshida H, Shibayama , Fujita T, Tsuyuki Y, Takahashi

BACKGROUND: The molecular characterization of Streptococcus dysgalactiae subsp. equisimilis (SDSE) has not yet been performed in Korea. This study aimed to find the differences or similarities in the clinical features,...
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The Evolving Epidemiology of Serotype Distribution and Antimicrobial Resistance of Streptococcus pneumoniae Strains Isolated from Adults in Crete, Greece, 2009–2016

Maraki S, Mavromanolaki VE, Stafylaki , Hamilos G, Samonis G

BACKGROUND: Pneumococcal disease is a major cause of morbidity and mortality worldwide, especially in patients with comorbidities and advanced age. This study evaluated trends in epidemiology of adult pneumococcal disease...
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Pharmacological treatment options for acne

Park KY

Acne vulgaris is a very common condition affecting up of about 80% to 90% of adolescents. The patients with acne have been shown to be adversely impacted by the effect...
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Screening of Antibiotics that Selectively Inhibit a Bacterial Species Associated with a Recurrent Aphthous Stomatitis Risk

Lee A, Kim Y, Choi Y

Recurrent aphthous stomatitis (RAS) is a common oral mucosal disorder for which no curative treatment is available. We previously reported that decreased Streptococcus salivarius and increased Acinetobacter johnsonii on the...
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Serotype Distribution of Invasive Group B Streptococcal Diseases in Infants at Two University Hospitals in Korea

Cho HK, Nam HN, Cho HJ, Son DW, Cho YK, Seo YH, Kim YJ, Eun BW

PURPOSE: This study was aimed at analyzing the serotypes of group B streptococcus (GBS) isolated from Korean infants with invasive disease and evaluating their association with disease manifestation. METHODS: Data were...
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In Vitro Diagnostic Testing for Antibiotic Allergy

Doña I, Torres MJ, Montañez , Fernández TD

Allergy to antibiotics is an important worldwide problem, with an estimated prevalence of up to 10% of the population. Reaction patterns for different antibiotics have changed in accordance with consumption...
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Throat Carriage Rate and Antimicrobial Resistance of Streptococcus pyogenes In Rural Children in Argentina

Delpech G, Sparo M, Baldaccini B, Pourcel G, Lissarrague S, García Allende L

OBJECTIVES: The aim of this study was to determine the prevalence of asymptomatic carriers of group A β-hemolytic streptococci (GAS) in children living in a rural community and to investigate...
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A Case of Methemoglobinemia Caused by Primaquine

Lee JY, Kim SH, An S, Oh HS, Yi SY, Lee HH, Han DJ

Primaquine is often administered for the hypnozoite stage of Plasmodium vivax and Plasmodium ovale. Primaquine (with clindamycin) is also an alternative drug for treatment of pneumocystis pneumonia when trimethoprim/sulfamethoxazole cannot...
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Characterization of Clostridium difficile Strains Isolated from Patients with C. difficile-associated Disease in Korea

Cho SH, Chon JW, Seo KH, Kim YK, Kim JB, Bak YS, Jung WW, Kim CH, Choi JT

OBJECTIVES: Studies on Clostridium difficile are rare in Korea. We investigated the epidemiological characteristics of C. difficile isolates from patients with C. difficile-associated disease (CDAD) in Korea. METHODS: Multiplex polymerase chain...
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Antimicrobial Susceptibility and Characterization of Propionibacterium acnes by Multilocus Sequence Typing and Repetitive-Sequence-Based PCR

Kim S, Song H, Lee WJ, Kim J

Propionibacterium acnes, a gram-positive, anaerobic, and aerotolerant bacterium that is found frequently in the skin as part of the human microbiome causes inflammatory acne, shoulder infection, and the contamination of...
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Distribution and Antimicrobial Resistance of Streptococcus pneumoniae at Four University Hospitals in Busan and Gyeongnam

Kim SH, Song SA, Yi J, Song D, Chang CL, Park DC, Urm SH, Kim HR, Shin JH

BACKGROUND: Streptococcus pneumoniae is the most common human pathogen causing community-acquired pneumonia. There is little information on the recent antimicrobial susceptibility patterns of S. pneumoniae in Busan and Gyeongnam of...
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Biocompatibility of two experimental scaffolds for regenerative endodontics

Leong DJ, Setzer FC, Trope M, Karabucak

OBJECTIVES: The biocompatibility of two experimental scaffolds for potential use in revascularization or pulp regeneration was evaluated. MATERIALS AND METHODS: One resilient lyophilized collagen scaffold (COLL), releasing metronidazole and clindamycin, was...
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