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Effects of Topical N-Acetylcysteine on Skin Hydration/Transepidermal Water Loss in Healthy Volunteers and Atopic Dermatitis Patients

Nakai K, Yoneda K, Murakami Y, Koura A, Maeda R, Tamai A, Ishikawa E, Yokoi I, Moriue J, Moriue T, Kubota Y

No abstract available.
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The Use of Matriderm and Autologous Skin Graft in the Treatment of Full Thickness Skin Defects

Min JH, Yun IS, Lew DH, Roh TS, Lee WJ

BACKGROUND: For patients with full thickness skin defects, autologous Split-thickness skin grafts (STSG) are generally regarded as the mainstay of treatment. However, skin grafts have some limitations, including undesirable outcomes...
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Effect of Emollients Containing Vegetable-Derived Lactobacillus in the Treatment of Atopic Dermatitis Symptoms: Split-Body Clinical Trial

Park SB, Im M, Lee Y, Lee JH, Lim J, Park YH, Seo YJ

BACKGROUND: Atopic dermatitis (AD) patients suffer from xerosis. Proper skin care, including the use of emollients, may help improve xerosis and minimize disease exacerbation. Lactobacillus sakei probio 65, isolated from...
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The Effect of Evening Primrose Oil for the Prevention of Xerotic Cheilitis in Acne Patients Being Treated with Isotretinoin: A Pilot Study

Park KY, Ko EJ, Kim IS, Li K, Kim BJ, Seo SJ, Kim MN, Hong CK

BACKGROUND: The most common adverse effects of oral isotretinoin are cheilitis, skin dryness, dry eyes, and conjunctivitis, whereas evening primrose oil (EPO) is known to improve skin moisture and transepidermal...
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Effect of air purifier on indoor air quality and atopic dermatitis

Park HC, Kim YH, Kim JE, Ko JY, Nam Goung , Lee CM, Kim YS, Ro YS

PURPOSE: High level of indoor air pollutant may cause aggravation of atopic diseases long with various allergic respiratory diseases especially in people who spend mostly of their lives indoors. The...
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Clinical use of a ceramide-based moisturizer for treating dogs with atopic dermatitis

Jung JY, Nam EH, Park SH, Han SH, Hwang CY

In humans, skin barrier dysfunction is thought to be responsible for enhanced penetration of allergens. Similar to conditions seen in humans, canine atopic dermatitis (CAD) is characterized by derangement of...
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Safety Evaluation of Stamp Type Digital Microneedle Devices in Hairless Mice

Park KY, Jang WS, Lim YY, Ahn JH, Lee SJ, Kim CW, Kim SE, Kim BJ, Kim MN

BACKGROUND: Microneedles provide a minimally invasive means to transport molecules into the skin. A number of specific strategies have been employed to use microneedles for transdermal delivery. OBJECTIVE: The purpose of...
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The Clinical Efficacy of Mometasone Furoate in Multi-Lamellar Emulsion for Eczema: A Double-blinded Crossover Study

Kim DH, Lee HJ, Park CW, Kim KH, Lee KH, Ro BI, Cho SH

BACKGROUND: Topical application of corticosteroids also has an influence on skin barrier impairment. Physiological lipid mixtures, such as multi-lamellar emulsion (MLE) containing a natural lipid component leads to effective recovery...
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Partial Seizures Manifesting as Apnea Only in Preterm Infant

Jun JK, Moon CJ, Kim SJ, Youn YA, Lee JY, Lee HS, Lee JH, Sung IK, Kim SY

PURPOSE: Extremely-low-birth-weight infants (ELBWIs), especially those < or =24 gestational weeks (GW), presented extremes in IWL and changes of water balance. The purpose of the present study was to retrospectively...
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Insensible Water Loss during the First Week of Life of Extremely Low Birth Weight Infants Less than 25 Gestational Weeks under High Humidification

Sung SI, Ahn SY, Seo HJ, Yoo HS, Han YM, Lee MS, Chang YS, Park WS

PURPOSE: Extremely-low-birth-weight infants (ELBWIs), especially those < or =24 gestational weeks (GW), presented extremes in IWL and changes of water balance. The purpose of the present study was to retrospectively...
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Changes in Transepidermal Water Loss and Skin Hydration according to Expression of Aquaporin-3 in Psoriasis

Lee Y, Je YJ, Lee SS, Li ZJ, Choi DK, Kwon YB, Sohn KC, Im M, Seo YJ, Lee JH

  • KMID: 2434682
  • Ann Dermatol.
  • 2012 May;24(2):168-174.
BACKGROUND: Aquaporins (AQPs) are a family of water transporting proteins present in many mammalian epithelial and endothelial cell types. Among the AQPs, AQP3 is known to be a water/glycerol transporter...
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Skin Characteristics in Patients with Pityriasis Versicolor Using Non-Invasive Method, MPA5

Park HJ, Lee YW, Choe YB, Ahn KJ

BACKGROUND: Skin pigmentary changes of pityriasis versicolor may occur as either hyperpigmented or hypopigmented lesions, depending on the outcome of interactions between Malassezia yeasts and the skin, such as lipoperoxidation...
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The Clinical Efficacy, Safety and Functionality of Anion Textile in the Treatment of Atopic Dermatitis

Kim SH, Hwang SH, Hong SK, Seo JK, Sung HS, Park SW, Shin JH

BACKGROUND: Several previous studies have suggested the improvement of atopic dermatitis (AD) in response to special fabrics. In particular, beneficial effects have been reported, following the use of anion textiles. OBJECTIVE:...
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Analysis of Colonization and Genotyping of the Exotoxins of Staphylococcus aureus in Patients with Atopic Dermatitis

Na SY, Roh JY, Kim JM, Tamang MD, Lee JR

BACKGROUND: The skin of atopic dermatitis (AD) patients has a high susceptibility to Staphylococcus aureus colonization, and the toxins produced by S. aureus may aggravate AD by acting as superantigens. OBJECTIVE:...
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Pseudoceramide-Containing Physiological Lipid Mixture Reduces Adverse Effects of Topical Steroids

Kim HJ, Park HJ, Yun JN, Jeong SK, Ahn SK, Lee SH

PURPOSE: Various therapeutic approaches have been suggested for preventing or reducing the adverse effects of topical glucocorticoids, including skin barrier impairment. Previously, we have shown that impairment of skin barrier...
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Skin Characteristics after Fractional Photothermolysis

Oh BH, Hwang YJ, Lee YW, Choe YB, Ahn KJ

  • KMID: 2383244
  • Ann Dermatol.
  • 2011 Nov;23(4):448-454.
BACKGROUND: Fractional photothermolysis makes thousands of minute areas called microthermal treatment zones on the skin surface and transmits thermal injury to facilitate heat shock protein formation around the dermis. Potential...
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Epidermal Hyperplasia and Elevated HB-EGF are More Prominent in Retinoid Dermatitis Compared with Irritant Contact Dermatitis Induced by Benzalkonium Chloride

Lee JE, Chang JY, Lee SE, Kim MY, Lee JS, Lee MG, Kim SC

BACKGROUND: 'Retinoid dermatitis' is a retinoid-induced irritant contact dermatitis (ICD). The mechanism of retinoid dermatitis may be different from that of other ICDs. However, it remains uncertain how topical retinoid...
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Effectiveness of Topical Chia Seed Oil on Pruritus of End-stage Renal Disease (ESRD) Patients and Healthy Volunteers

Jeong SK, Park HJ, Park BD, Kim IH

BACKGROUND: Several studies have been performed to evaluate the efficacy of dietary n-3 fatty acid for patients with renal dysfunction. While about 40% to 80% of patients with end-stage renal...
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Changes of Antimicrobial Peptides and Transepidermal Water Loss After Topical Application of Tacrolimus and Ceramide-dominant Emollient in Patients with Atopic Dermatitis

Park KY, Kim DH, Jeong MS, Li K, Seo SJ

Increased transepidermal water loss (TEWL) and downregulated antimicrobial peptides (AMPs) are observed in patients with atopic dermatitis (AD). Tacrolimus and ceramide-dominant emollients are effective in the treatment of AD by...
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Assessment of Hydration on the Stratum Corneum and the Influencing Factors in Neonates

Ahn Y, Shin E

  • KMID: 1375002
  • J Korean Acad Nurs.
  • 2007 Aug;37(5):781-789.
PURPOSE: The study was conducted to investigate the skin hydration level in various body sites and identify the influencing factors in neonates. METHODS: An exploratory comparison study was designed...
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