- Expression of Matrix Metalloproteinases and Its Inhibitor in Gastric Adenocarcinoma
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Lim SC
- KMID: 2166229
- Cancer Res Treat.
- 2001 Jun;33(3):199-206.
PURPOSE: Matrix metalloproteinases (MMPs) have been associated with tumor cell invasion and metastasis by mediating the degradation of extracellular matrix components. A tissue inhibitor of metalloproteinases (TIMPs) has been reported... -
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- Immunodetections of the Metalloproteinase (MMP-2 and MMP-9) and Tissue Inhibitor of Metalloproteinases (TIMP-2) in Prostatic Adenocarcinomas
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Kim SS, Woo YJ, Huh J, Yoon H, Park JM, Kim M
- KMID: 1906176
- J Korean Cancer Assoc.
- 1997 Jun;29(3):445-453.
PURPOSE: The metalloproteinases (MMP) and their inhibitors (TIMP) have been suggested to play a role in tumor invasion and metastasis. There have been some dispute on the exact role of... -
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- Clinical significance of the serum levels of matrix metalloproteinases and the tissue inhibitors of metalloproteinases for gastric and colorectal cancer patients
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Yoon SJ, Shim KN, Cho YK, Song HJ, Jung SA, Kim TH, Yoo K
- KMID: 2256411
- Korean J Med.
- 2007 May;72(5):491-500.
BACKGROUND: Matrix metalloproteinases (MMPs) and their inhibitors, the tissue inhibitors of metalloproteinase (TIMPs), are important factors related to invasion and metastasis in various human cancers. Different results have been reported... -
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- Expression of Matrix Metalloproteinase (MMP)-2, MMP-9, Tissue Inhibitor of Metalloproteinase (TIMP)-1 and TIMP-2 in Adenocarcinomas of The Gallbladder
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Bae JY, Choi J, Chung HC, Park C, Park YN
- KMID: 1725949
- Korean J Pathol.
- 2003 Feb;37(1):1-9.
BACKGROUND: Matrix metalloproteinase (MMP)-2 and MMP-9 degrade type IV collagen and are antagonized by the tissue inhibitors of metalloproteinase (TIMP)-2 and TIMP-1, respectively. METHODS: We studied by immunohistochemistry the expressions of... -
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- Expression of Matrix Metallopreoteinases and Tissue Inhibitors of Metalloproteinases in Ulcerative Colitis
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Kim SE, Jung SA, Shim KN, Jung HK, Kim TH, Yoo K
- KMID: 2174115
- Intest Res.
- 2009 Jun;7(1):32-40.
BACKGROUND/AIMS: Ulcerative colitis (UC) is characterized by chronic non-specific inflammation in the mucosa and submucosa of the colon. Degradation of the extracellular matrix (ECM) is one of the major events... -
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- Expression of Matrix Metalloproteinase-2 and -13 and Tissue Inhibitor of Metalloproteinase-4 in Varicose Veins
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Chang JW, Maeng YH, Kim SW
- KMID: 1447769
- Korean J Thorac Cardiovasc Surg.
- 2011 Dec;44(6):387-391.
- doi: 10.5090/kjtcs.2011.44.6.387
BACKGROUND: The relationship between the degree of expression of matrix metalloproteinases or tissue inhibitor of metalloproteinases and venous reflux remains to be investigated. MATERIALS AND METHODS: Primary varicose vein tissues were... -
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- Comparison Study between Immunohistochemical Staining and Enzyme Linked Immunosorbent Assay in Metalloproteinases and Tissue inhibitor of Metalloproteinases in Virus induced Myocarditis
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Hong YM, Kim SS
- KMID: 2207692
- J Korean Pediatr Soc.
- 1999 Nov;42(11):1524-1534.
PURPOSE: Most tissue disruption of extracellular matrix is mediated by extracellular proteinases. Matrix metalloproteinases(MMP) and tissue inhibitor of matrix metalloproteinases(TIMP) are associated with wound healing and repair. There has been... -
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- The Effects of Botulinum Toxin A on Collagen Synthesis, Expression of MMP (matrix metalloproteinases)-1,2,9 and TIMP (tissue inhibitors of metalloproteinase)-1 in the Keloid Fibroblasts
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Roh TS, Hong JW, Lee WJ, Yoo HS, Lew DH, Kim YS
- KMID: 2266920
- Arch Aesthetic Plast Surg.
- 2013 Jun;19(2):114-119.
- doi: 10.14730/aaps.2013.19.2.114
Keloids are characterized by excessive extracelluar matrix (ECM) deposition such as collagen, fibronectin, elastin, and proteoglycans in the dermis. Recently, the use of botulinum toxin A (BTXA) in the treatment... -
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- Clinical significance of matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 and 2 in Kawasaki disease
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Yun KW, Yun SW, Lee JJ, Chae SA, Lim IS, Choi ES, Yoo BH, Lee MK
- KMID: 2073576
- Korean J Pediatr.
- 2010 Apr;53(4):510-518.
- doi: 10.3345/kjp.2010.53.4.510
PURPOSE: Kawasaki disease (KD) is a systemic vasculitis, a leading cause of pediatric acquired heart disease. Histopathological findings of coronary artery lesion (CAL) in KD indicate destruction of the coronary... -
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- The expressions of inflammatory factors and tissue inhibitor of matrix metalloproteinase-2 in human chronic periodontitis with type 2 diabetes mellitus
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Shin DS, Park JW, Suh JY, Lee JM
- KMID: 2094713
- J Periodontal Implant Sci.
- 2010 Feb;40(1):33-38.
- doi: 10.5051/jpis.2010.40.1.33
PURPOSE: The purpose of this study was to observe and quantify the expression of interleukin-4 (IL-4), interferon-gamma (IFN-gamma), and tissue inhibitor of matrix metalloproteinase-2 (TIMP-2) in the gingival tissue of... -
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- The influence of type 2 diabetes mellitus on the expression of inflammatory mediators and tissue inhibitor of metalloproteinases-2 in human chronic periodontitis
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Kim JB, Jung MH, Cho JY, Park JW, Suh JY, Lee JM
- KMID: 1783600
- J Periodontal Implant Sci.
- 2011 Jun;41(3):109-116.
- doi: 10.5051/jpis.2011.41.3.109
PURPOSE: The purpose of this study was to compare and quantify the expression of C-reactive protein (CRP), matrix metalloproteinase (MMP)-14, and tissue inhibitor of metalloproteinases (TIMP)-2 in gingival tissues of... -
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- Differential Expression of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Thioacetamide-Induced Chronic Liver Injury
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Park SY, Shin HW, Lee KB, Lee MJ, Jang JJ
- KMID: 1792927
- J Korean Med Sci.
- 2010 Apr;25(4):570-576.
- doi: 10.3346/jkms.2010.25.4.570
Hepatic fibrogenesis, a complex process that involves a marked accumulation of extracellular matrix components, activation of cells capable of producing matrix materials, cytokine release, and tissue remodeling, is regulated by... -
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- The expression of a nitric oxide derivative, tissue inhibitors of metalloproteinase-3, and tissue inhibitors of metalloproteinase-4 in chronic periodontitis with type 2 diabetes mellitus
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Jung HY, Kim YG, Park JW, Suh JY, Lee JM
- KMID: 2329640
- J Periodontal Implant Sci.
- 2013 Apr;43(2):87-95.
PURPOSE: The purpose of this study was to analyze the expression of inducible nitric oxide synthases (iNOS), tissue inhibitors of metalloproteinase (TIMP)-3, and TIMP-4 in the gingival tissues of periodontal... -
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- Relaxin Modulates the Expression of MMPs and TIMPs in Fibroblasts of Patients with Carpal Tunnel Syndrome
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Kang YM, Lee HM, Moon SH, Kang H, Choi YR
- KMID: 2427132
- Yonsei Med J.
- 2017 Mar;58(2):415-422.
- doi: 10.3349/ymj.2017.58.2.415
PURPOSE: The aim of this study was to investigate the anti-fibrotic effect of relaxin in subsynovial fibroblasts activated by transforming growth factor beta (TGF-β). MATERIALS AND METHODS: To test the anti-fibrotic... -
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- Overexpression of tissue inhibitors of metalloproteinase-1 and -2 in the stroma of gastric cancer
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Hong SI, Park IC, Hong WS, Son YS, Lee SH, Lee JI, Choi DW, Moon NM, Choe TB, Jang JJ
- KMID: 645010
- J Korean Med Sci.
- 1996 Dec;11(6):474-479.
- doi: 10.3346/jkms.1996.11.6.474
The fundamental event of cancer invasion and metastasis is the complicated interaction of cancer cells with host cells, in which event, a number of proteases and their inhibitors are involved.... -
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- Comparison of Corticosteroids by 3 Approaches to the Treatment of Chronic Rhinosinusitis With Nasal Polyps
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Zhang Y, Lou H, Wang Y, Li Y, Zhang L, Wang C
- KMID: 2448751
- Allergy Asthma Immunol Res.
- 2019 Jul;11(4):482-497.
- doi: 10.4168/aair.2019.11.4.482
PURPOSE: Corticosteroids are regarded as the mainstay of medical treatment of eosinophilic chronic rhinosinusitis with nasal polyps (ECRSwNP). To date, a head-to-head comparison of the efficacy and safety of glucocorticoid... -
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- Effect of Hijikia fusiforme extracts on degenerative osteoarthritis in vitro and in vivo models
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Kwon HO, Lee M, Kim OK, Ha Y, Jun W, Lee J
- KMID: 2342128
- Nutr Res Pract.
- 2016 Jun;10(3):265-273.
- doi: 10.4162/nrp.2016.10.3.265
BACKGROUND/OBJECTIVES: The inhibitory effect of Hijikia fusiforme (HF) extracts on degenerative osteoarthritis was examined in primary cultured rat cartilage cells and a monosodium iodoacetate (MIA)-induced osteoarthritis rat model. MATERIALS/METHODS: In vitro,... -
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- The Expression of Matrix Metalloproteinases (MMPs), Tissue Inhibitor of Metalloproteinases (TIMPs) and Angiogenesis in Relation to the Depth of Tumor Invasion and Lymph Node Metastasis in Submucosally Invasive Colorectal Carcinoma
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Jung SA, Yang SK, Kim JS, Shim KN, Im SA, Myung SJ, Jung HY, Yu CS, Kim JC, Hong WS, Kim JH, Min YI
- KMID: 772787
- Korean J Gastroenterol.
- 2005 Jun;45(6):401-408.
BACKGROUND/AIMS: Lymph node (LN) metastasis occurs in approximately 10% of patients with submucosally invasive colorectal carcinoma. This study was performed to determine the role of matrix metalloproteinases (MMPs), tissue... -
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- Chlamydophila pneumoniae enhances secretion of VEGF, TGF-beta and TIMP-1 from human bronchial epithelial cells under Th2 dominant microenvironment
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Park CS, Kim TB, Moon KA, Bae YJ, Lee HR, Jang MK, Moon HB, Cho YS
- KMID: 2260418
- Allergy Asthma Immunol Res.
- 2010 Jan;2(1):41-47.
- doi: 10.4168/aair.2010.2.1.41
PURPOSE: Chlamydophila pneumoniae infection in the airways is thought to be associated with the pathogenesis of asthma, especially in non-atopic severe asthma with irreversible airway obstruction that may be related... -
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- The Identification of Immune-Related Plasma Proteins Associated with Spontaneous Preterm Delivery and Intra-Amniotic Infection in Women with Premature Cervical Dilation or an Asymptomatic Short Cervix
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Park H, Hong S, Yoo HN, Kim YM, Lee SJ, Park KH
- KMID: 2470777
- J Korean Med Sci.
- 2020 Feb;35(7):e26.
- doi: 10.3346/jkms.2020.35.e26
BACKGROUND: We aimed to investigate whether various immune-related plasma proteins, alone or in combination with conventional clinical risk factors, can predict spontaneous preterm delivery (SPTD) and intra-amniotic infection in women... -
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