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Role of COX-2 and PPAR in Gastric Carcinogenesis

Yeo M, Hahm KB

  • KMID: 1113299
  • Korean J Gastroenterol.
  • 2004 Jul;44(1):53-56.
No abstract available.
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Gastric Accumulation of Bone Seeking Agent in a Patient with Advanced Gastric Cancer

Kim DW, Jeong HJ, Park SA, Kim CG

Soft tissue uptake of Tc-99m labeled bone seeking agents, such as Tc-99m 3,3-diphosphono-1,2-propanedicarboxylic acid (DPD), is commonly seen in clinical practice, even though bone scintigraphy is mainly used to detect...
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Expression of Beta-catenin and E-cadherin in Early Gastric Cancer: Correlation with Clinicopathologic Parameters

Song BJ, Park YJ, Kim HS, Kim CN, Chang SH

  • KMID: 772610
  • Korean J Gastroenterol.
  • 2004 Feb;43(2):82-89.
BACKGROUND/AIMS: Beta-catenin is known to perform two unrelated functions in cadherin-mediated cell to cell adhesion system and Wnt pathway. Recent studies reported cytoplasmic and nuclear accumulation of beta-catenin by...
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Overexpression of nicotinamide N-methyltransferase in gastric cancer tissues and its potential post-translational modification

Lim BH, Cho BI, Kim YN, Kim JW, Park ST, Lee CW

  • KMID: 1098079
  • Exp Mol Med.
  • 2006 Oct;38(5):455-465.
Gastric cancer is one of the most common cancers worldwide. The purpose of this study was to find out potential markers for gastric cancer. Tumor and normal tissues from 152...
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Mucin histochemistry by paradoxical concanavalin A staining in early gastric carcinomas

Cho KJ, Myong HH, Jang JJ

Phenotypic expression of tumor cells was investigated in 33 early gastric carcinomas by mucin histochemistry using paradoxical concanavalin A staining. This staining method had been developed to differentiate 3 classes...
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Comparison of bromodeoxyuridine and proliferating cell nuclear antigen labeling in gastric carcinoma

Kang SM, Kim WH, Kim CW, Kim YI

The proliferative activity of human gastric carcinoma was measured by means of in vitro incorporation of the thymidine analogue, 5-bromo-2'-deoxyuridine (BrdU), into the newly-synthesized DNA of fresh tumors and immunohistochemical...
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Epstein-Barr Virus, Beta-Catenin, and E-cadherin in Gastric Carcinomas

Jung IM, Chung JK, Kim YA, Kim JE, Heo SC, Ahn YJ, Hwang KT, Kim BG, Lee KL, Kim CW, Kim WH, Chang MS

Activated beta-catenin is suggested to inhibit NF-kappaB activation, and we previously demonstrated that NF-kappaB nuclear positivity was more frequent in Epstein-Barr virus (EBV)-infected gastric carcinomas. It is controversial that beta-catenin...
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The Proteomics Approach to Find Biomarkers in Gastric Cancer

Ryu JW, Kim HJ, Lee YS, Myong NH, Hwang CH, Lee GS, Yom HC

Gastric cancer is a very serious disease and is naturally resistant to many anticancer drugs. To reduce the mortality and improve the effectiveness of therapy, many studies have tried to...
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Significance of Preoperative Tissue Levels of Vascular-endothelial Cadherin, Liver-intestine Cadherin and Vascular Endothelial Growth Factor in Gastric Cancer

Ryu KH, Shim KN, Jung SA, Yoo K, Joo YH, Lee JH

BACKGROUND/AIMS: The aims of this study were to examine the expressions of endothelium specific VE-cadherin, intestine specific LI-cadherin, and vascular endothelial growth factor (VEGF), and to determine their relationships with...
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Immunohistochemical Expression of Bcl-2, Bcl-xL, Bax, p53 Proteins in Gastric Adenoma and Adenocarcinoma

Lee DS, Kang SB, Baek JT, Nam SW, Lee KM, Ahn BM, Lee EH, Han SW, Chung IS

  • KMID: 772786
  • Korean J Gastroenterol.
  • 2005 Jun;45(6):394-400.
BACKGROUND/AIMS: The aim of this study was to investigate the immunohistochemical expression of bcl-2, bcl-xL, bax, and p53 proteins according to the pathological parameters such as grade of dysplasia,...
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Synergistic effect of peroxiredoxin II antisense on cisplatin-induced cell death

Yoo YD, Chung YM, Park JK, Ahn CM, Kim SK, Kim HJ

  • KMID: 931877
  • Exp Mol Med.
  • 2002 Sep;34(4):273-277.
Peroxiredoxin II (Prx II) is known not only to protect cells from oxidative damage caused by hydrogen peroxide (H2O2), but also to endow cancer cells with resistance to both...
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Expression of c-erbB-2 and c-met Proteins in Gastric Adenoma and Adenocarcinoma

Lee SW, Kang SB, Kim YS, Nam SW, Lee DS, Lee HK, Han SW

  • KMID: 782837
  • Korean J Gastroenterol.
  • 2007 Mar;49(3):152-157.
BACKGROUND/AIMS: The aim of this study was to investigate the immunohistochemical overexpression of c-erbB-2 and c-met proteins according to the histopathological parameters such as grade of dysplasia, histological type, depth...
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Isoprenaline Induces Periostin Expression in Gastric Cancer

Liu GX, Xi HQ, Sun XY, Geng ZJ, Yang SW, Lu YJ, Wei B, Chen L

PURPOSE: Periostin mediates critical steps in gastric cancer and is involved in various signaling pathways. However, the roles of periostin in promoting gastric cancer metastasis are not clear. The aim...
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Transcriptional induction of DLC-1 gene through Sp1 sites by histone deacetylase inhibitors in gastric cancer cells

Kim TY, Kim IS, Jong HS, Lee JW, Kim TY, Jung M, Bang YJ

We previously reported that trichostatin A (TSA), a histone deacetylase (HDAC) inhibitor, induced DLC-1 mRNA expression and accumulated acetylated histones H3 and H4 associated with the DLC-1 promoter in DLC-1...
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Measurement of Peritoneal Fluid pH in Patients with Non-Serosal Invasive Gastric Cancer

Noh SM

The accurate pH range of peritoneal fluid is clinically valuable for the evaluation of some pathological conditions of the body, however, it is not easy to measure in healthy individuals....
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Expression of urokinase: type plasminogen activator, its receptor, and its inhibitor in gastric adenocarcinoma tissues

Hong SI, Park IC, Son YS, Lee SH, Kim BG, Lee JI, Lee TW, Kook YH, Min YI, Hong WS

The plasminogen and plasmin system, which is mainly regulated by urokinase-type plasminogen activator (uPA), its receptor (uPAR) and its inhibitor (PAI-1), is generally believed to play a role in cancer...
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Expression of Cyclin Dependent Kinase Inhibitors of KIP Family in Gastric Cancer

Lee SJ, Joo YE, Kim HS, Choi SK, Rew JS, Park CS, Kim SJ

  • KMID: 1113428
  • Korean J Gastroenterol.
  • 2005 Aug;46(2):84-93.
BACKGROUND/AIMS: The cyclin-dependent kinase inhibitors (CDKI) including p21, p27, and p57 of the kinase inhibitor protein (KIP) family are negative regulators of cell cycle progression and potentially act as...
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Role of Cyclooxygenase-2 (COX-2) and Peroxisome Proliferator-Activated Receptor (PPAR) in Gastric Cancer

Chang YW, Cho HL, Jang JY, Dong SH, Kim HJ, Kim BH, Lee JI, Chang R

  • KMID: 1112282
  • Korean J Gastroenterol.
  • 2004 May;43(5):291-298.
BACKGROUND/AIMS: Gastric cancer is still the most frequently diagnosed malignancy in Korea. It has been reported that COX-2 and PPAR are involved in multi-step gastric carcinogenesis. The aim of...
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