- Functional roles of Na+/H+ exchanger isoforms in saliva secretion
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Park K, Evans RL, Melvin JE
- KMID: 1026932
- J Korean Med Sci.
- 2000 Aug;15(Suppl):S5-S6.
- doi: 10.3346/jkms.2000.15.S.S5
No abstract available. -
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- A novel Na+-dependent transporter and NHE3 mediate H+ efflux in the luminal membrane of the pancreatic duct: regulation by cAMP
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Lee MG, Ahn W, Choi JY, Muallem S, Kim KH
- KMID: 1026941
- J Korean Med Sci.
- 2000 Aug;15(Suppl):S29-S30.
- doi: 10.3346/jkms.2000.15.S.S29
No abstract available. -
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- Kidney and Phosphate Metabolism
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Choi NW
- KMID: 2134809
- Electrolyte Blood Press.
- 2008 Dec;6(2):77-85.
- doi: 10.5049/EBP.2008.6.2.77
The serum phosphorus level is maintained through a complex interplay between intestinal absorption, exchange intracellular and bone storage pools, and renal tubular reabsorption. The kidney plays a major role in... -
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- Altered Renal Expression of Acid-base Transporters in Rats with Glycerol-induced Tubular Injury
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Ma SK, Bae EH, Lee J, Kim SW
- KMID: 2116770
- Chonnam Med J.
- 2010 Dec;46(3):163-169.
- doi: 10.4068/cmj.2010.46.3.163
The present study aimed to investigate the altered regulation of renal tubular acid-base transporters in rats with glycerol-induced tubular injury. Male Sprague-Dawley rats were used. Rats were injected with 50%... -
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- Altered Regulation of NHE3, NBC1 and Nitric Oxide System in the Kidney of Rats with Maleic Acid-nduced Metabolic Acidosis
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Ma SK
- KMID: 1597799
- Korean J Nephrol.
- 2006 Jul;25(4):543-550.
PURPOSE: The present study was aimed to determine whether there exist an altered regulation of tubular transporters and nitric oxide system in the kidneys in maleic acid-nduced metabolic acidosis. METHODS: Male... -
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- A Novel Polyclonal Antiserum against Toxoplasma gondii Sodium Hydrogen Exchanger 1
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Xiao B, Kuang Z, Zhan Y, Chen D, Gao Y, Li M, Luo S, Hao W
- KMID: 2374013
- Korean J Parasitol.
- 2016 Feb;54(1):21-29.
- doi: 10.3347/kjp.2016.54.1.21
The sodium hydrogen exchanger 1 (NHE1), which functions in maintaining the ratio of Na+ and H+ ions, is widely distributed in cell plasma membranes. It plays a prominent role in... -
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- Alkali Therapy Attenuates the Progression of Kidney Injury via Na/H Exchanger Inhibition in 5/6 Nephrectomized Rats
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Kim S, Lee J, Heo NJ, Lee JW, Han JS
- KMID: 1786112
- J Korean Med Sci.
- 2014 May;29(5):691-698.
- doi: 10.3346/jkms.2014.29.5.691
Metabolic acidosis is a cause of renal disease progression, and alkali therapy ameliorates its progression. However, there are few reports on the role of renal acid-base transporters during alkali therapy.... -
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- Altered Regulation of Renal Acid Base Transporters in Response to Ammonium Chloride Loading in Rats
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Kim EY, Choi JS, Lee KE, Kim CS, Bae EH, Ma SK, Kim SH, Lee JU, Kim SW
- KMID: 2071753
- Korean J Physiol Pharmacol.
- 2012 Apr;16(2):91-95.
- doi: 10.4196/kjpp.2012.16.2.91
The role of the kidney in combating metabolic acidosis has been a subject of considerable interest for many years. The present study was aimed to determine whether there is an... -
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- Changes in the expression of c-myc, RB and tyrosine-phosphorylated proteins during proliferation of NIH 3T3 cells induced by hyaluronic acid
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Moon SO, Lee JH, Kim TJ
- KMID: 754984
- Exp Mol Med.
- 1998 Mar;30(1):29-33.
We have shown that hyaluronic acid stimulates the proliferation of quiescent NIH 3T3 cells. We have shown that treatment of 1 mg/ml hyaluronic acid results in increase of tyrosine phosphorylation of two... -
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- Altered Renal Sodium Transporter Expression in an Animal Model of Type 2 Diabetes Mellitus
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Oh YK, Joo KW, Lee JW, Jeon US, Lim CS, Han JS, Knepper MA, Na KY
- KMID: 1785766
- J Korean Med Sci.
- 2007 Dec;22(6):1034-1041.
- doi: 10.3346/jkms.2007.22.6.1034
Hemodynamic factors play an important role in the development and/or progression of diabetic nephropathy. We hypothesized that renal sodium transporter dysregulation might contribute to the hemodynamic alterations in diabetic nephropathy.... -
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- Oxidative Stress-Activated NHE1 Is Involved in High Glucose-Induced Apoptosis in Renal Tubular Epithelial Cells
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Wu Y, Zhang M, Liu R, Zhao C
- KMID: 2374173
- Yonsei Med J.
- 2016 Sep;57(5):1252-1259.
- doi: 10.3349/ymj.2016.57.5.1252
PURPOSE: Diabetic nephropathy (DN) is a prevalent chronic microvascular complication of diabetes mellitus involving disturbances in electrolytes and the acid-base balance caused by a disorder of glucose metabolism. NHE1 is... -
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- Intracellular acidosis decreases the outward Na(+)-Ca2+ exchange current in guinea pig ventricular myocytes
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Lee EH, Park SR, Paik KS, Suh CK
- KMID: 699820
- Yonsei Med J.
- 1995 Apr;36(2):146-152.
- doi: 10.3349/ymj.1995.36.2.146
The Na(+)-Ca2+ exchange transport operating in outward mode has been suggested to cause Ca2+ entry during reperfusion or reoxygenation, exchanging extracellular Ca2+ for intracellular Na+ that has accumulated during ischemia... -
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- Increased Expression of Sodium Transporters in Rats Chronically Inhibited of Nitric Oxide Synthesis
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Kim JS, Choi KC, Jeong MH, Kim SW, Oh YW, Lee JU
- KMID: 2157772
- J Korean Med Sci.
- 2006 Feb;21(1):1-4.
- doi: 10.3346/jkms.2006.21.1.1
The present study was done to determine whether endogenous nitric oxide (NO) plays a role in the regulation of sodium transporters in the kidney. Male Sprague-Dawley rats were treated with... -
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- Effects of Thiazide on the Expression of TRPV5, Calbindin-D28K, and Sodium Transporters in Hypercalciuric Rats
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Jang HR, Kim S, Heo NJ, Lee JH, Kim HS, Nielsen S, Jeon US, Oh YK, Na KY, Joo KW, Han JS
- KMID: 1778157
- J Korean Med Sci.
- 2009 Jan;24(Suppl 1):S161-S169.
- doi: 10.3346/jkms.2009.24.S1.S161
TRPV5 is believed to play an important role in the regulation of urinary calcium excretion. We assessed the effects of hydrochlorothiazide (HCTZ) on the expression of TRPV5, calbindin-D28K, and several... -
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- High Dose Vitamin D3 Attenuates the Hypocalciuric Effect of Thiazide in Hypercalciuric Rats
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Jang HR, Lee JW, Kim S, Heo NJ, Lee JH, Kim HS, Jung JY, Oh YK, Na KY, Han JS, Joo KW
- KMID: 1785909
- J Korean Med Sci.
- 2010 Sep;25(9):1305-1312.
- doi: 10.3346/jkms.2010.25.9.1305
Thiazide is known to decrease urinary calcium excretion. We hypothesized that thiazide shows different hypocalciuric effects depending on the stimuli causing hypercalciuria. The hypocalciuric effect of hydrochlorothiazide (HCTZ) and the... -
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- Angiotensin II AT1 Receptor Blockade Changes Expression of Renal Sodium Transporters in Rats with Chronic Renal Failure
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Kim EJ, Jung YW, Kwon TH
- KMID: 1095199
- J Korean Med Sci.
- 2005 Apr;20(2):248-255.
- doi: 10.3346/jkms.2005.20.2.248
We aimed to examine the effects of angiotensin II AT1 receptor blocker on the expression of major renal sodium transporters and aquaporin-2 (AQP2) in rats with chronic renal failure (CRF).... -
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