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A Case of Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type with Dermatomyositis

Gong Y, Xue K, Hu Y, Wei R, Liu Y, Cao H, Shi Y

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Lack of association between the VEGFA gene polymorphisms and preterm birth in Korean women

Shi Y, Kim HJ, Kim SY, Kim GE, Jin HJ

Preterm birth (PTB), a pregnancy-related disease, is defined as a birth before 37 weeks of gestation. It is a major cause of maternal mortality and morbidity worldwide, and its incidence...
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Expression of FMD virus-like particles in yeast Hansenula polymorpha and immunogenicity of combine with CpG and aluminum adjuvant

Zhang J, Ge J, Li J, Li J, Zhang Y, Shi Y, Sun J, Wang Q, Zhang X, Zhao X

Background: Inactivated vaccines are limited in preventing foot-and-mouth disease (FMD) due to safety problems. Recombinant virus-like particles (VLPs) are an excellent candidate for a novel vaccine for preventing FMD, given...
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Characteristics of progestin-insensitive early stage endometrial cancer and atypical hyperplasia patients receiving second-line fertility-sparing treatment

Zhou S, Xu Z, Yang B, Guan J, Shan W, Shi Y, Chen X

Objective This study investigated the characteristics of progestin-insensitive endometrioid endometrial cancer (EEC) and atypical endometrial hyperplasia (AEH) patients receiving fertility-sparing treatments and assessed the therapeutic effects of second-line fertility-preserving treatments. Methods Three hundred...
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Ectopic Over-expression of Oncogene Pim-2 Induce Malignant Transformation of Nontumorous Human Liver Cell Line L02

Ren K, Duan W, Shi Y, Li B, Liu Z, Gong J

In order to prove that ectopic over-expression of Pim-2 could induce malignant transformation of human liver cell line L02, three groups of cells were set up including human liver cell...
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Oleanolic acid induced autophagic cell death in hepatocellular carcinoma cells via PI3K/Akt/mTOR and ROS-dependent pathway

Shi Y, Song Q, Hu D, Zhuang X, Yu S, Teng D

Oleanolic acid (OA) has a wide variety of bioactivities such as hepatoprotective, anti-inflammatory and anti-cancer activity and is used for medicinal purposes in many Asian countries. In the present study,...
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Quantitative Tracking Tumor Suppression Efficiency of Human Umbilical Cord-Derived Mesenchymal Stem Cells by Bioluminescence Imaging in Mice Hepatoma Model

Liu J, Shi Y, Han J, Zhang Y, Cao Z, Cheng J

Background and Objectives: Tracking of the tumor progression by MSCs-based therapy is being increasingly important in evaluating relative therapy effectively. Herein, Bioluminescence imaging (BLI) technology was used to dynamically and...
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Expression and evaluation of porcine circovirus type 2 capsid protein mediated by recombinant adenoassociated virus 8

Li S, Wang B, Jiang S, Lan X, Qiao Y, Nie J, Yin Y, Shi Y, Kong W, Shan Y

Background: Porcine circovirus type 2 (PCV2) is an important infectious pathogen implicated in porcine circovirus-associated diseases (PCVAD), which has caused significant economic losses in the pig industry worldwide. Objectives: A suitable...
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Association Between Metabolic Risk Factors and Cognitive Impairment in Schizophrenia Based on Sex

Huang H, Du L, Pu Z, Shi Y, Xiao Z, Chen X, Yao S, Wang L, Li Z, Xue T, Cui D

Objective Sex differences have been observed in many aspects of schizophrenia, including cognitive deficits. Despite extensive research into the relationship between metabolic factors and cognitive deficits in schizophrenia, few studies...
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Gadoxetate-Enhanced MRI as a Diagnostic Tool in the Management of Hepatocellular Carcinoma: Report from a 2020 Asia-Pacific Multidisciplinary Expert Meeting

Tan CH, Chou Sc, Inmutto N, Ma K, Sheng R, Shi Y, Zhou Z, Yamada A, Tateishi R

Gadoxetate magnetic resonance imaging (MRI) is widely used in clinical practice for liver imaging. For optimal use, we must understand both its advantages and limitations. This article is the outcome...
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Efficacy of Sublingual Immunotherapy for House Dust Mite-Induced Allergic Rhinitis: A Meta-Analysis of Randomized Controlled Trials

Feng B, Xiang H, Jin H, Gao J, Huang S, Shi Y, Chen R, Chen B

PURPOSE: Allergic rhinitis (AR) has become a global issue for a large part of the general population. Sublingual immunotherapy (SLIT) has been used extensively to treat persistent allergic rhinitis (PAR)....
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Effects of dietary salt intake restriction on blood glucose levels: a meta-analysis of crossover study

Shen Y, Shi Y, Cui J, He H, Ren S

BACKGROUND/OBJECTIVES: To identify modifiable risk factors for type 2 diabetes mellitus and explore the relationship between diet sodium intake and blood glucose levels. MATERIALS/METHODS: Based on inclusion and exclusion criteria, we...
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The Feasibility of Using Biomarkers Derived from Circulating Tumor DNA Sequencing as Predictive Classifiers in Patients with Small-Cell Lung Cancer

Feng Y, Liu Y, Yuan M, Dong G, Zhang H, Zhang T, Chang L, Xia X, Li L, Zhu H, Xing P, Wang H, Shi Y, Wang Z, Hu X

Purpose To investigate the feasibility of biomarkers based on dynamic circulating tumor DNA (ctDNA) to classify small cell lung cancer (SCLC) into different subtypes. Materials and Methods Tumor and longitudinal...
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Lineage conversion of mouse fibroblasts to pancreatic α-cells

Liu T, Sun L, Jiang B, Li L, Cen J, Chen X, Zhang Z, Wang Q, Cheng X, Shi Y, Hui L

α-cells, which synthesize glucagon, also support β-cell survival and have the capacity to transdifferentiate into β-cells. However, the role of α-cells in pathological conditions and their putative clinical applications remain...
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Excessive Daytime Sleepiness and Insomnia Symptoms in Adolescents With Major Depressive Disorder: Prevalence, Clinical Correlates, and the Relationship With Psychiatric Medications Use

Shi Y, Li W, Chen C, Yuan X, Yang Y, Wang S, Liu Z, Geng F, Wang J, Luo X, Wen X, Xia L, Liu H

Objective Excessive daytime sleepiness (EDS) and insomnia symptoms are common in patients with major depressive disorder (MDD), which might lead to a poor prognosis and an increased risk of depression...
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Overexpression of miR-155-5p Inhibits the Proliferation and Migration of IL-13-Induced Human Bronchial Smooth Muscle Cells by Suppressing TGF-β-Activated Kinase 1/MAP3K7-Binding Protein 2

Shi Y, Fu X, Cao Q, Mao Z, Chen Y, Sun Y, Liu Z, Zhang Q

PURPOSE: Molecular mechanisms leading to asthma is still ill-defined. Though the function of microRNAs (miRNAs) in asthma was previously reported, the involvement of miR-155 in important features of this disease...
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Protein-centric omics analysis reveals circulating complements linked to non-viral liver diseases as potential therapeutic targets

Shi Y, Dong H, Sun S, Wu X, Fang J, Zhao J, Han J, Li Z, Wu H, Liu L, Wu W, Tian Y, Yuan G, Fan X, Xu C

Background/Aims: To evaluate the causal correlation between complement components and non-viral liver diseases and their potential use as druggable targets. Methods: We conducted Mendelian randomization (MR) to assess the causal role...
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