Psychiatry Investig.
2023 Nov;20(11):1018-1026. 10.30773/pi.2023.0013.
Excessive Daytime Sleepiness and Insomnia Symptoms in Adolescents With Major Depressive Disorder: Prevalence, Clinical Correlates, and the Relationship With Psychiatric Medications Use
- Shi Y
1,2,3 - Li W1
- Chen C4
- Yuan X1
- Yang Y1,2,3
- Wang S1,2,3
- Liu Z5
- Geng F6
- Wang J7
- Luo X8
- Wen X9
- Xia L1,2,3
- Liu H1,2,3
- Affiliations
-
- 1Department of Psychiatry, Chaohu Hospital of Anhui Medical University, Hefei, Anhui, China
- 2Department of Psychiatry, School of Mental Health and Psychological Sciences, Anhui Medical University, Hefei, Anhui, China
- 3Anhui Psychiatric Center, Anhui Medical University, Hefei, Anhui, China
- 4Department of Psychiatry, Suzhou Second People’s Hospital, Suzhou, Anhui, China
- 5Department of Psychiatry, Fuyang Third People’s Hospital, Fuyang, Anhui, China
- 6Department of Psychiatry, Hefei Fourth People’s Hospital, Hefei, Anhui, China
- 7Department of Psychiatry, Bozhou People’s Hospital, Bozhou, Anhui, China
- 8Department of Psychiatry, The Second Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China
- 9Department of Psychiatry, Ma’anshan Fourth People’s Hospital, Ma’anshan, Anhui, China
- KMID: 2547990
- DOI: http://doi.org/10.30773/pi.2023.0013
Abstract
Objective
Excessive daytime sleepiness (EDS) and insomnia symptoms are common in patients with major depressive disorder (MDD), which might lead to a poor prognosis and an increased risk of depression relapse. The current study aimed to investigate the prevalence, and sociodemographic and clinical correlates of EDS and insomnia symptoms among adolescents with MDD.
Methods
The sample of this cross-sectional study included 297 adolescents (mean age=15.26 years; range=12–18 years; 218 females) with MDD recruited from three general and four psychiatric hospitals in five cities (Hefei, Bengbu, Fuyang, Suzhou, and Ma’anshan) in Anhui Province, China between January and August, 2021. EDS and insomnia symptoms, and clinical severity of depressive symptoms were assessed using Epworth sleepiness scale, Insomnia Severity Index, and Clinical Global Impression-Severity.
Results
The prevalence of EDS and insomnia symptoms in adolescents with MDD was 39.7% and 38.0%, respectively. Binary logistic regression analyses showed that EDS symptoms were significantly associated with higher body mass index (odds ratio [OR]=1.097, 95% confidence interval [CI]=1.027–1.172), more severe depressive symptoms (OR=1.313, 95% CI=1.028–1.679), and selective serotonin reuptake inhibitors use (OR=2.078, 95% CI=1.199–3.601). And insomnia symptoms were positively associated with female sex (OR=1.955, 95% CI=1.052–3.633), suicide attempts (OR=1.765, 95% CI=1.037–3.005), more severe depressive symptoms (OR=2.031, 95% CI=1.523–2.709), and negatively associated with antipsychotics use (OR=0.433, 95% CI=0.196–0.952).
Conclusion
EDS and insomnia symptoms are common among adolescents with MDD. Considering their negative effects on the clinical prognosis, regular screening and clinical managements should be developed for this patient population.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Exploration of Insomnia With Excessive Daytime Sleepiness From Clinical and Polysomnographic Perspectives
- The Sleepy Child
- An update on the cause and treatment of sleep disturbance in children and adolescents with autism spectrum disorder
- Clinical and Polysomnographic Characteristics of Patients Complaining of Excessive Daytime Sleepiness and/or Insomnia
- Correlations between Symptoms of Sleep Apnea and Respiration during Sleep
