- Rutin induces autophagy in cancer cells
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Park MH, Kim S, Song YR, Kim S, Kim HJ, Na HS, Chung J
- KMID: 2162146
- Int J Oral Biol.
- 2016 Mar;41(1):45-51.
- doi: 10.11620/IJOB.2016.41.1.045
Rutin (3,3′,4′,5,7-pentahydroxyflavone-3-rhamnoglucoside) is a bioactive flavonoid from the plant kingdom. Rutin has been studied as potential anticancer agent due to its wide range of pharmacological properties including antioxidative, anti-inflammatory and... -
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- The Effect of Rutin on the Melanogenesis and Nitric Oxide in UVB-irradiated HM3KO Human Melanoma
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Lee SY, Kim YM, Lee JK, Yoo SJ, Mun YJ, Woo WH
- KMID: 1894517
- Korean J Anat.
- 2003 Feb;36(1):49-56.
Ultraviolet (UV) radiation is the main physiological stimulus for human skin pigmentation. Recently, nitric oxide (NO) have been involved in mediation of skin pigmentation induced by UVB. Rutin, a flavonoid... -
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- Rutin inhibits osteoclast formation by decreasing reactive oxygen species and TNF-alpha by inhibiting activation of NF-kappaB
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Kyung TW, Lee JE, Shin HH, Choi HS
- KMID: 1103588
- Exp Mol Med.
- 2008 Feb;40(1):52-58.
- doi: 10.3858/emm.2008.40.1.52
Rutin, a glycoside of flavonol, inhibits osteoclast formation induced by receptor activator of NF-kappaB ligand (RANKL) in bone marrow-derived macrophages. It reduces reactive oxygen species produced by RANKL and its... -
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- Effects of Watercress Containing Rutin and Rutin Alone on the Proliferation and Osteogenic Differentiation of Human Osteoblast-like MG-63 Cells
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Hyun H, Park H, Jeong J, Kim J, Kim H, Oh HI, Hwang HS, Kim HH
- KMID: 2285530
- Korean J Physiol Pharmacol.
- 2014 Aug;18(4):347-352.
- doi: 10.4196/kjpp.2014.18.4.347
Most known osteoporosis medicines are effective for bone resorption, and so there is an increasing demand for medicines that stimulate bone formation. Watercress (N. officinale R. Br.) is widely used... -
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- Content Analysis of Rutin in the Leaves of Boehmeria nivea Harvested in Different Regions of South Korea by HPLC-UV
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Cho S, Quilantang NG, Lee JS, Kim YM, Kim HB, Cho EJ, Jung YS, Lee S
- KMID: 2409607
- Nat Prod Sci.
- 2018 Mar;24(1):36-39.
- doi: 10.20307/nps.2018.24.1.36
Phytochemical analysis of Boehmeria nivea (Bn) leaves by medium pressure liquid chromatography led to the isolation of a flavonoid glycoside identified by spectroscopic analysis as rutin. The amount of rutin... -
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- Comparative Effects of Dietary Quercetin and Rutin in Rats Fed with the Lieber-DeCarli Ethanol Diet
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Seo SJ, Park CH, Ko IY, Jeong YH, Choi YS
- KMID: 2393805
- Nat Prod Sci.
- 2017 Sep;23(3):222-226.
- doi: 10.20307/nps.2017.23.3.222
Flavonoids including quercetin and rutin are a group of naturally occurring compounds widely distributed in plants, especially in buckwheat. Thus, cereal and the leaf of the plant have increasingly used... -
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- The Effects of Free Radical Scavenger, Rutin, on the Development and the Cell Number of Blastocyst in Mouse Early Embryos
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Hwang KJ, Kwon HC, Ryu HS, Kim HS, Yang HW, Oh KS
- KMID: 1924377
- Korean J Obstet Gynecol.
- 1997 May;40(5):941-946.
It is well known that developmental delay or arrest occurs before implantation inmammals, which have undergone in vitro culture. Recently, these phenomenon are being attributedto oxygen free radicals, and... -
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- Identification and HPLC Quantification of a Phytoecdysone and Three Phenolic Glycosides in Lamium takesimense Nakai
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Nugroho A, Park KS, Seo DJ, Park HJ
- KMID: 2432418
- Nat Prod Sci.
- 2018 Dec;24(4):241-246.
- doi: 10.20307/nps.2018.24.4.241
The herbs of Lamium takesimense Nakai (Lamiaceae) is used to treat spasmodic and inflammatory disease. The four polar compounds, ecdysterone, isoacteoside, rutin and lamiuside C, were isolated and identified from... -
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- Influence of rutin on the effects of neonatal cigarette smoke exposure-induced exacerbated MMP-9 expression, Th17 cytokines and NF-κB/iNOS-mediated inflammatory responses in asthmatic mice model
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Liu LL, Zhang Y, Zhang XF, Li FH
- KMID: 2418998
- Korean J Physiol Pharmacol.
- 2018 Sep;22(5):481-491.
- doi: 10.4196/kjpp.2018.22.5.481
Allergic asthma is one of the most enduring diseases of the airway. The T-helper cells and regulatory T-cells are critically involved in inflammatory responses, mucus hypersecretion, airway remodelling and in... -
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- Protective effect of rutin on splanchnic injury following ischemia and reperfusion in rats
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Lee HM, Jang YY, Song JH, Kim KJ, Lim IJ, Shin YK
- KMID: 2071572
- Korean J Physiol Pharmacol.
- 2001 Aug;5(4):323-331.
A splanchic artery occlusion for 90 min followed by reperfusion of the mesenteric circulation resulted in a severe form of circulatory shock characterized by endothelial dysfunction, severe hypotension, marked intestinal tissue injury, and... -
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- Quantitative Analysis of the Flavonoid Content in the Leaves of Boehmeria nivea and Related Commercial Products
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Lee DG, Cho S, Lee J, Yang S, Jung YS, Kim HB, Cho EJ, Lee S
- KMID: 2409602
- Nat Prod Sci.
- 2015 Mar;21(1):66-70.
- doi: 10.0000/nps.2015.21.1.66
Content analysis of flavonoids (epicatechin, epicatechin gallate, and rutin) present in the leaves of Boehmeria nivea (originating from Geumsan-myeon, Biin-myeon, Hansan-myeon, and Baeksu-eup) and their commercial products (ramie tteok, ramie... -
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- Phytochemical Identification from Boehmeria nivea Leaves and Analysis of (-)-Loliolide by HPLC
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Cho S, Lee DG, Jung YS, Kim HB, Cho EJ, Lee S
- KMID: 2328880
- Nat Prod Sci.
- 2016 Jun;22(2):134-139.
- doi: 10.20307/nps.2016.22.2.134
Phytochemicals were isolated from leaves of the fiber crop, ramie (Boehmeria nivea, Bn), using open column chromatography and medium pressure liquid chromatography. Their structures were identified as β-sitosterol, (-)-loliolide, rutin,... -
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- Anti-Proliferative Effects of Rutin on OLETF Rat Vascular Smooth Muscle Cells Stimulated by Glucose Variability
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Yu SH, Yu JM, Yoo HJ, Lee SJ, Kang DH, Cho YJ, Kim DM
- KMID: 2374042
- Yonsei Med J.
- 2016 Mar;57(2):373-381.
- doi: 10.3349/ymj.2016.57.2.373
PURPOSE: Proliferation of vascular smooth muscle cells (VSMCs) plays a crucial role in atherosclerosis. Rutin is a major representative of the flavonol subclass of flavonoids and has various pharmacological activities.... -
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- Increased Flavonoid Compounds from Fermented Houttuynia cordata using Isolated Six of Bacillus from Traditionally Fermented Houttuynia cordata
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Kwon RH, Ha BJ
- KMID: 1432249
- Toxicol Res.
- 2012 Jun;28(2):117-122.
Flavonoids, which form a major component in Houttuynia cordata Thunb., display a wide range of pharmacological activities. The expression of plant flavonoids is partly regulated by fermentation. Therefore, we studied... -
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- Role of Group II Phospholipase A2 in the Pulmonary Oxidative Stress of the Acute Lung Injury Induced by Gut Ischemia-Reperfusion
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Jheon S, Kim K, Lee SC, Kim SE, Lee YM, Lee JT
- KMID: 1916133
- Korean J Thorac Cardiovasc Surg.
- 2002 Jul;35(7):501-510.
BACKGROUND: The various pathogeneses of acute respiratory distress syndrome have been suggested but not established yet. In the present study, the role of group II phospholipase A2(PLA2) in the pathogenesis... -
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- Protective Effect of Flavonoids on Lymphocyte DNA Damage Using Comet Assay
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Park YK, Jeon EJ, Kang MH
- KMID: 2269636
- Korean J Nutr.
- 2003 Mar;36(2):125-132.
The present study was attempted to investigate and compare the antioxidant potency of several well-know flavonoids, antioxidant vitamin and commercially available popular beverages. The antioxidant potency was assessed by the... -
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- Comparison of Antioxidant Activities of Some Flavonoids
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Jung HG, Jung MA, Song DU, Ahn BW, Yang SY
- KMID: 1807457
- Chonnam Med J.
- 2000 Jun;36(2):159-166.
This study was aimed to evaluate the relative antioxidant activities of some common flavonoids such as quercetin, rutin, catechin, epicatechin gallate (ECG) and epigallocatechin gallate (EGCG). The antioxidant activities were... -
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- Differential Effects of Quercetin and Quercetin Glycosides on Human α7 Nicotinic Acetylcholine Receptor-Mediated Ion Currents
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Lee BH, Choi SH, Kim HJ, Jung SW, Hwang SH, Pyo MK, Rhim H, Kim HC, Kim HK, Lee SM, Nah SY
- KMID: 2351690
- Biomol Ther.
- 2016 Jul;24(4):410-417.
- doi: 10.4062/biomolther.2015.153
Quercetin is a flavonoid usually found in fruits and vegetables. Aside from its antioxidative effects, quercetin, like other flavonoids, has a various neuropharmacological actions. Quercetin-3-O-rhamnoside (Rham1), quercetin-3-O-rutinoside (Rutin), and quercetin-3-(2(G)-rhamnosylrutinoside... -
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- Sonchus asper extract inhibits LPS-induced oxidative stress and pro-inflammatory cytokine production in RAW264.7 macrophages
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Wang L, Xu ML, Liu J, Wang Y, Hu JH, Wang MH
- KMID: 2313880
- Nutr Res Pract.
- 2015 Dec;9(6):579-585.
- doi: 10.4162/nrp.2015.9.6.579
BACKGROUND/OBJECTIVES: Sonchus asper is used extensively as an herbal anti-inflammatory for treatment of bronchitis, asthma, wounds, burns, and cough; however, further investigation is needed in order to understand the underlying... -
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