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Diagnosis of canine brucellosis using recombinant ribosomal protein L7/L12

Lee HK, Kim JW, Ha YM, Her M, Kim JY, Lee K, Kang SI, Jung SC

  • KMID: 1435796
  • Korean J Vet Res.
  • 2012 Mar;52(1):25-31.
Brucella (B.) canis is mainly transmitted by direct or indirect contact with aborted fetuses and placenta. It's also known to be able to infect human, which likely results in providing...
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Phosphorylation of ribosomal protein S6 and its regulation during differentiation of human leukemic cells

Kim IS, Lee SB, Cho KC

We attempted to study the role of protein tyrosine kinase (PTK) and protein kinase C (PKC) in the cascade of phosphorylation of ribosomal protein S6 during differentiation of leukemic cells...
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Differential Protein Expressions in Virus-Infected and Uninfected Trichomonas vaginalis

He D, Pengtao G, Ju Y, Jianhua L, He L, Guocai Z, Xichen Z

Protozoan viruses may influence the function and pathogenicity of the protozoa. Trichomonas vaginalis is a parasitic protozoan that could contain a double stranded RNA (dsRNA) virus, T. vaginalis virus (TVV)....
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Molecular cloning of ribosomal P protein in Toxoplasma gondii and the availability to detect antibody against recombinant protein in toxoplasmosis patients

Ahn HJ, Kim S, Nam HW

Among the panel of monoclonal antibodies (mAb) against Toxoplasma gondii, mAb of Tg621 (Tg621) clone blotted 38 kDa protein which localized in the cytoplasm of tachyzoites by immunofluorescence microscopy. The...
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Screening and Cloning of Genes Preferentially Expressed in Aminopterin-Treated Myeloma Cell Apoptosis

Lee HC, Kim SJ, Yoon S, Kwon SJ, Chung YH

  • KMID: 2175032
  • J Korean Cancer Assoc.
  • 2000 Jun;32(3):655-664.
PURPOSE: When murine myeloma cells P3-X63-Ag8.653 (V653) of this model treated with amin opterin, an anticancer drug, they can't synthesize nucleic acid via de novo or salvage pathway and selectively eliminated due...
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Linezolid Resistance in Methicillin-Resistant Staphylococcus aureus in Korea: High Rate of False Resistance to Linezolid by the VITEK 2 System

Yoo IY, Kang OK, Shim HJ, Huh HJ, Lee NY

As various linezolid resistance mechanisms have been identified in methicillin-resistant Staphylococcus aureus (MRSA), we investigated the molecular characteristics of MRSA with elevated linezolid minimum inhibitory concentrations (MICs), using the VITEK...
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Detection of genetic mutations associated with macrolide resistance of Mycoplasma pneumoniae

Oh CE, Choi EH, Lee HJ

PURPOSE: The aim of this study was to identify mutations associated with macrolide resistance in Mycoplasma pneumoniae (MP) and to establish a cultural method to determine antimicrobial susceptibility. METHODS: Nasopharyngeal aspirates...
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Analysis of Low Molecular Weight Proteome from H. pylori Cell Extract Using the High Performance Liquid Chromatography

Park JW, Lee KJ, Kim KM, Joo JS, Kwon YC, Youn HS, Song JY, Kang HL, Lee KH, Baik SC, Lee WK, Cho MJ, Rhee KH

Low molecular proteins (LMPs) which are smaller than 20 kDa are difficult to visible on a standard two-dimensional SDS-polyacrylamide gel electrophoresis (2-D SDS-PAGE) map. LMPs must be enriched appropriately to...
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Gene Expression Profile of Lung Cancer Cells Following Photodynamic Therapy

Sung JH, Lee ME, Han SS, Lee SJ, Ha KS, Kim WJ

BACKGROUND: Photodynamic therapy is a viable option for lung cancer treatment, and many studies have shown that it is capable of inducing cell death in lung cancer cells. However, the...
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Molecular Epidemiology and Mechanisms of 43 Low-Level Linezolid-Resistant Enterococcus faecalis Strains in Chongqing, China

Hua R, Xia Y, Wu W, Yang M, Yan J

BACKGROUND: Enterococcus faecalis strains with low-level resistance to linezolid (an oxazolidinone antibiotic) have become common. No large-scale study has examined the underlying mechanisms in linezolid-resistant E. faecalis (LRE) strains. We...
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Change in the Gene Expression of HOS Cell Line by 17beta-Estradiol -Study using cDNA Array-

Yoo CI, Suh JT, Kim JI, Kim CM

  • KMID: 2199153
  • J Korean Orthop Res Soc.
  • 2000 Apr;3(1):78-95.
Osteoporosis is caused by the decrease in bone mass associated with disturbance in bone remodeling. Bone remodeling depends on the spatial and temporal coupling of bone formation by osteoblasts and...
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Neuroprotective Effect of Rapamycin in Optic Nerve Transection Model

Kim SH, Han YK, Park KH, Kim YJ

PURPOSE: The present study investigated whether rapamycin activated autophagy in retinal ganglion cells (RGC) and evaluated its effect on RGC survival following optic nerve transection (ONT). METHODS: The activation of autophagy...
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Altered Gene Expression in Cerulein-Stimulated Pancreatic Acinar Cells: Pathologic Mechanism of Acute Pancreatitis

Yu JH, Lim JW, Kim H

Acute pancreatitis is a multifactorial disease associated with the premature activation of digestive enzymes. The genes expressed in pancreatic acinar cells determine the severity of the disease. The present study...
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Imaging Mass Spectrometry in Papillary Thyroid Carcinoma for the Identification and Validation of Biomarker Proteins

Min KW, Bang JY, Kim KP, Kim WS, Lee SH, Shanta SR, Lee JH, Hong JH, Lim SD, Yoo YB, Na CH

Direct tissue imaging mass spectrometry (IMS) by matrix-assisted laser desorption ionization and time-of-flight (MALDI-TOF) mass spectrometry has become increasingly important in biology and medicine, because this technology can detect the...
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Omadacycline, a Magic Antibiotics for Bacterial Infections

Rahman MS, Koh YS

Nowadays antibiotic resistance is a worldwide serious problem that mainly affects public health. Omadacycline is a unique antibiotic which has two available dosage forms such as intravenous (IV) and oral...
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Molecular cloning and characterization of porcine ribosomal protein L21

Sun WS, Chun JL, Kim DH, Ahn JS, Kim MK, Hwang IS, Kwon DJ, Hwang S, Lee JW

Ribosomal protein L21 (RPL21) is a structural component of the 60S subunit of the eukaryotic ribosome. This protein has an important role in protein synthesis and the occurrence of hereditary...
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Immunodeficiency Virus Type 1 Infection of H9 Cells

Nam JG, Kim KC, Jeon SK, Kim SS, Lee SW, An SW, Lee JS

  • KMID: 2054987
  • J Bacteriol Virol.
  • 2004 Mar;34(1):57-66.
Human immunodeficiency virus type 1 (HIV-1) virus causes severe defect in the immune system and affects the host cell gene expression profoundly. The gene expression pattern will be characterized by...
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Ribosomal Protein L19 and L22 Modulate TLR3 Signaling

Yang EJ, Seo JW, Choi IH

BACKGROUND: Toll-like receptor 3 (TLR3) recognizes double-stranded RNA (dsRNA) and induces inflammation. In this study we attempted to ascertain if there are endogenous host molecules controlling the production of cytokines...
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The cDNA microarray study for the effect of FGF-5 administration on fibroblast

Kim WT, Cho NS, Shin SS, Kim SG, Park YH, Park YJ, Park JW, Rhee JG

  • KMID: 1580276
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2004 Jan;26(1):15-23.
Immunosuppresant induced gingival hyperplasia was a common complication in organ transplantation patients. However, its exact mechanism had been remained unknown. In previous study, FGF-5 and FGF-7 were overexpressed in gingival...
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Diverse Immunoprofile of Ductal Adenocarcinoma of the Prostate with an Emphasis on the Prognostic Factors

Jeong SU, Kekatpure , Park JM, Han M, Hwang HS, Jeong HJ, Go H, Cho YM

BACKGROUND: Ductal adenocarcinoma (DAC) of the prostate is an uncommon histologic subtype whose prognostic factors and immunoprofile have not been fully defined. METHODS: To define its prognostic factors and immunoprofile, the...
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