- Anti-inflammatory Effect of Mangosteen (Garcinia mangostana L.) Peel Extract and its Compounds in LPS-induced RAW264.7 Cells
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Widowati W, Darsono L, Suherman J, Fauziah N, Maesaroh M, Erawijantari PP
- KMID: 2355138
- Nat Prod Sci.
- 2016 Sep;22(3):147-153.
- doi: 10.20307/nps.2016.22.3.147
Inflammation plays an important role in host defense against external stimuli such as infection by pathogen, endotoxin or chemical exposure by the production of the inflammatory mediators that produced by... -
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- Role of Rotavirus Enterotoxin NSP4 in the Inflammatory Response in Murine Macrophage RAW 264.7 Cells
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Kim SA, Than VT, Kim W
- KMID: 2366867
- J Bacteriol Virol.
- 2016 Dec;46(4):221-230.
- doi: 10.4167/jbv.2016.46.4.221
The rotavirus nonstructural glycoprotein, NSP4, has been identified as the first viral enterotoxin capable of inducing diarrhea. To investigate the biological function of NSP4 in the inflammatory process, a cDNA... -
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- Anti-inflammatory Activity of Standardized Fraction from Inula helenium L. via Suppression of NF-κB Pathway in RAW 264.7 Cells
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Chun J, Song K, Kim YS
- KMID: 2443098
- Nat Prod Sci.
- 2019 Mar;25(1):16-22.
- doi: 10.20307/nps.2019.25.1.16
Inula helenium L. is rich source of eudesmane-type sesquiterpene lactones, mainly alantolactone and isoalantolactone, which have the various pharmacological functions. In this study, we examined the inhibitory effects of nitric... -
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- Inhibitory Effect of Ginsenosides Rh1 and Rg2 on Oxidative Stress in LPS-Stimulated RAW 264.7 Cells
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Jin Y, Baek N, Back S, Myung CS, Heo KS
- KMID: 2452068
- J Bacteriol Virol.
- 2018 Dec;48(4):156-165.
- doi: 10.4167/jbv.2018.48.4.156
Minor ginsenosides Rh1 and Rg2 were isolated from Korean red ginseng and reported to have various biological effects on anti-inflammatory and anti-stress activities. However, the effects of Rh1 and Rg2... -
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- Magnoliae Cortex and maize modulate Porphyromonas gingivalis-induced inflammatory reactions
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Kim JY, Kim KH, Kwag EH, Seol YJ, Lee YM, Ku Y, Rhyu IC
- KMID: 2410686
- J Periodontal Implant Sci.
- 2018 Apr;48(2):70-83.
- doi: 10.5051/jpis.2018.48.2.70
PURPOSE: The aim of this study was to evaluate the capacity of single and combined applications of the bark of the stems and roots of Magnolia officinalis Rehd. et Wils.... -
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- Luteolin 5-O-glucoside from Korean Milk Thistle, Cirsium maackii, Exhibits Anti-Inflammatory Activity via Activation of the Nrf2/HO-1 Pathway
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Jung HA, Roy A, Abdul QA, Kim HR, Park HJ, Choi JS
- KMID: 2393799
- Nat Prod Sci.
- 2017 Sep;23(3):183-191.
- doi: 10.20307/nps.2017.23.3.183
Luteolin 5-O-glucoside is the major flavonoid from Korean thistle, Cirsium maackii. We previously reported the anti-inflammatory activities of luteolin 5-O-glucoside in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. In this study, we... -
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- Inhibitory Activity of Cordyceps bassiana Extract on LPS-induced Inflammation in RAW 264.7 Cells by Suppressing NF-κB Activation
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Yoon DH, Han C, Fang Y, Gundeti S, Han Lee IS, Song WO, Hwang KC, Kim TW, Sung GH, Park H
- KMID: 2393796
- Nat Prod Sci.
- 2017 Sep;23(3):162-168.
- doi: 10.20307/nps.2017.23.3.162
Cordyceps bassiana has long been used as an oriental medicine and reported to possess diverse biological activities. The fruiting bodies of Cordyceps bassiana was extracted with ethanol and then further... -
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- Bioassay-Guided Isolation and Identification of Compounds from Arecae Pericarpium with Anti-inflammatory, Anti-oxidative, and Melanogenesis Inhibition Activities
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Indriana A, Lee KJ, Kim YS
- KMID: 2355145
- Nat Prod Sci.
- 2016 Sep;22(3):193-200.
- doi: 10.20307/nps.2016.22.3.193
This study describes the anti-inflammatory, anti-oxidant, and melanogenesis inhibition activities of methanol extract and various organic solvent fractions of Arecae Pericarpium. We examined the inhibition of lipopolysaccharide (LPS)-induced nitric oxide... -
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- Chemical Constituents from Buddleja officinalis and Their Inhibitory Effects on Nitric Oxide Production
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Park TW, Lee C, Lee JW, Jang H, Jin Q, Lee MK, Hwang BY
- KMID: 2328879
- Nat Prod Sci.
- 2016 Jun;22(2):129-133.
- doi: 10.20307/nps.2016.22.2.129
Bioactivity-guided fractionation of a methanolic extract of Buddleja officinalis led to the isolation of two monoterpenes, crocusatin M (1), crocusatin C (2), a flavonoid, acacetin (3), three lignans, lariciresinol (4),... -
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- Inhibitory Effect of a Sesquiterpene from Artemisia iwayomogi on Expression of Inducible Nitric Oxide Synthase by Suppression of I-κBα Degradation in LPS-stimulated RAW 264.7 Cells
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Kim NY, Koh HJ, Li H, Lee HJ, Ryu JH
- KMID: 2387057
- Nat Prod Sci.
- 2017 Jun;23(2):92-96.
- doi: 10.20307/nps.2017.23.2.92
A sesquiterpene was purified from Artemisia iwayomogi methanolic extract during the course of searching anti-inflammatory principle from medicinal plants. A sesquiterpene identified as armefolin inhibited the production of nitric oxide... -
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- Anti-inflammatory effects of proanthocyanidin-rich red rice extract via suppression of MAPK, AP-1 and NF-κB pathways in Raw 264.7 macrophages
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Limtrakul , Yodkeeree , Pitchakarn P, Punfa W
- KMID: 2342126
- Nutr Res Pract.
- 2016 Jun;10(3):251-258.
- doi: 10.4162/nrp.2016.10.3.251
BACKGROUND/OBJECTIVES: Several pharmacological properties of red rice extract have been reported including anti-oxidant, anti-tumor, and reduced cancer cell invasion. This study was conducted to evaluate the anti-inflammatory effects of red... -
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- Inhibition of Osteoclast differentiation based on precipitation time of titanium surfaces immersed in modified simulated body fluid
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Chang HM, Heo SJ, Kim SK, Koak JY
- KMID: 2444183
- J Korean Acad Prosthodont.
- 2019 Apr;57(2):142-149.
- doi: 10.4047/jkap.2019.57.2.142
PURPOSE: The purpose of this study is to investigate the changes of osteoclast differentiation inhibition according to the period of precipitation when titanium disks were immersed in Modified simulated body... -
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- Anti-inflammatory activities of Scolopendra subspinipes mutilans in RAW 264.7 cells
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Park JH, Lee SR
- KMID: 2419503
- J Nutr Health.
- 2018 Aug;51(4):323-329.
- doi: 10.4163/jnh.2018.51.4.323
PURPOSE: The dried body of Scolopendra subspinipes mutilans has long been used as a traditional Korean medicinal food, but little is known about its mechanisms of action. In this study,... -
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- Protective Effects of S-Adenosylmethionine and Its Combinations With Taurine and/or Betaine Against Lipopolysaccharide or Polyinosinic-polycytidylic Acid-induced Acute Hepatotoxicity
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Lee SY, Ko KS
- KMID: 2367573
- J Cancer Prev.
- 2016 Sep;21(3):152-163.
- doi: 10.15430/JCP.2016.21.3.152
BACKGROUND: Several mechanisms for the pathogenesis of many liver diseases are related with oxidative stress, endotoxins, and infections by many microorganisms. These can lead to chronic hepatitis, cirrhosis, and even... -
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- Estragole Exhibits Anti-inflammatory Activity with the Regulation of NF-κB and Nrf-2 Signaling Pathways in LPS-induced RAW 264.7 cells
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Roy A, Park HJ, Jung HA, Choi JS
- KMID: 2409604
- Nat Prod Sci.
- 2018 Mar;24(1):13-20.
- doi: 10.20307/nps.2018.24.1.13
Estragole is a naturally occurring phenylpropanoid obtained from essential oils found in a broad diversity of plants. Although the phenylpropanoids show many biological activities, clear regulation of the inflammatory signaling... -
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- Anti-melanogenesis and Anti-inflammatory Effects of Cinnamomi Cortex Extract In Vitro
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Park JH, Park SJ, Park KY, Kim BJ
- KMID: 2465952
- Korean J Dermatol.
- 2019 Sep;57(8):448-456.
BACKGROUND: Many researchers have sought to identify safe, natural herbal extracts that exert an anti-melanogenesis effect. Cinnamomi cortex has been widely used as a herbal medicine in Asia and Europe. OBJECTIVE:... -
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- Pulegone Exhibits Anti-inflammatory Activities through the Regulation of NF-κB and Nrf-2 Signaling Pathways in LPS-stimulated RAW 264.7 cells
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Roy A, Park HJ, Abdul QA, Jung HA, Choi JS
- KMID: 2409606
- Nat Prod Sci.
- 2018 Mar;24(1):28-35.
- doi: 10.20307/nps.2018.24.1.28
Pulegone is a naturally occurring organic compound obtained from essential oils from a variety of plants. The aim of this study was to investigate the anti-inflammatory effects through the inhibitory... -
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- Effects of the cathepsin K inhibitor with mineral trioxide aggregate cements on osteoclastic activity
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Kim HS, Kim S, Ko H, Song M, Kim M
- KMID: 2446665
- Restor Dent Endod.
- 2019 May;44(2):e17.
- doi: 10.5395/rde.2019.44.e17
OBJECTIVES: Root resorption is an unexpected complication after replantation procedures. Combining anti-osteoclastic medicaments with retrograde root filling materials may avert this resorptive activity. The purpose of this study was to... -
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- The activation of NLRP3-inflammsome by stimulation of diesel exhaust particles in lung tissues from emphysema model and RAW 264.7 cell line
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Uh ST, Koo SM, Kim Y, Kim K, Park S, Jang AS, Kim D, Kim YH, Park CS
- KMID: 2411489
- Korean J Intern Med.
- 2017 Sep;32(5):865-874.
- doi: 10.3904/kjim.2016.033
BACKGROUND/AIMS: Diesel exhaust particles (DEPs) lead to elevation of reactive oxygen species, which can activate the nucleotide-binding oligomerization domain-like receptor (NLR) family members containing the pyrin domain 3 (NLRP3)-inf lammasome.... -
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- Regulation of Inflammation by Sucrose Isomer, Turanose, in Raw 264.7 Cells
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Chung JY, Kim YS, Kim Y, Yoo SH
- KMID: 2396169
- J Cancer Prev.
- 2017 Sep;22(3):195-201.
- doi: 10.15430/JCP.2017.22.3.195
Increased sugar consumption has been proposed to be a risk factor for obesity-related metabolic disorders. The objective of this study was to investigate the anti-inflammatory effect of turanose in Raw... -
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