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Cefepime-induced neurotoxicity

Lee SJ

Cefepime, a widely used fourth-generation cephalosporin, has been reported to cause neurotoxicity because it crosses the blood-brain barrier. Although cefepime-induced neurotoxicity (CIN) occurs in patients with renal dysfunction administered a...
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A Case of Neurotoxicity Following 5-Fluorouracil-based Chemotherapy

Ki SS, Jeong JM, Kim SH, Jeong SH, Lee JH, Han CJ, Kim YC, Lee JO, Hong YJ

  • KMID: 1758683
  • Korean J Intern Med.
  • 2002 Mar;17(1):73-77.
5-Fluorouracil (5-FU) is a commonly used chemotherapeutic agent. However, its neurotoxicity is rare and not well recognized. We report a case of 5-FU neurotoxicity with organic brain syndrome and progression...
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Neonatal anesthesia: how we manage our most vulnerable patients

Bang SR

Neonates undergoing surgery are at higher risk than older children for anesthesia-related adverse events. During the perioperative period, the maintenance of optimal hemodynamics in these patients is challenging and requires...
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Tacrolimus related neurologic complication after pediatric kidney transplantation

Kwun WH

Recently significant neurotoxicity has been reported with the use of carcineurin inhibitors. An 11-year-old-girl had undergone a transplantation of kidney from her mother. On post-operative day 12, hypertension, headache, and...
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Neurotoxicity Induced by Cefepime in a Patient with Minimal Change Disease

Baek SD, Park SJ, Baek CH, Koo TY, Kang JK, Kim SB

  • KMID: 2080122
  • Korean J Nephrol.
  • 2010 Nov;29(6):796-801.
A 71-year-old woman with minimal change disease visited our clinic complaining of pleuritic chest pain. Cefepime was given under the impression that she had pneumonia. Three days after cefepime administration,...
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The potential risks of sugammadex

Lee W

Sugammadex provides fast and safe recovery from neuromuscular blockade without causing major adverse effects, and its clinical use is increasing. However, there are some reports on the potential risks of...
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Toxic encephalopathy in a worker exposed to organic solvents; a case report

Cheon YH

  • KMID: 1694424
  • Korean J Occup Environ Med.
  • 1991 Nov;3(2):216-219.
No abstract available.
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Bilateral Lesions in the Posterior Limb of Internal Capsule Attributed to Combination Therapy of Isoniazid and Rifampin

Park MW, Roh J, Im S, Kim MO, Kim YS, Kang J, Kim DH, Kwon OY

Transient isoniazid-induced brain lesions have rarely been reported. The lesions were in the dentate nucleus of cerebellum and thalamus. Meanwhile, the neurotoxicity of rifampin has not been reported evidently. We...
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Antibiotics Induced Seizures and Encephalopathy

Cho KH

Drug-induced seizures and delirium are common among patients with critical illnesses, especially those in an intensive care unit. With an increase in the use of potent, broad-spectrum antibiotics, the etiology...
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A Case of Neurotoxicity Induced by Valaciclovir in a Continuous Ambulatory Peritoneal Dialysis Patient

Kim JS, Yang JE, Lee BY, Lee S, Park HJ, Lee S, Lee SK

Valaciclovir is metabolized to acyclovir after ingestion and thereafter exerts its antiviral activity. Because of its superior pharmacokinetic profile, it has quickly replaced acyclovir in the treatment of herpesvirus infection....
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Lipid Emulsion in the Successful Resuscitation of Local Anesthetic Toxicity after Ankle Block

Park SH, Kwak SH, Yoo KY, Lee HJ, Yook KB, Kim SJ

Unexpected occurrence of local anesthetic toxicity is not rare and can cause fatal complications that do not respond to any known drug of intervention. Recently, the successful use of lipid...
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Acute Cerebral Infarction after FK 506 Administration in a Kidney Transplantation Recipient: A Case Report

Lim JK, Byun WM, Kim JW

FK506 is widely used as a potent immunosuppressive agent following organ transplantation. However, the use of FK506 is associated with a wide spectrum of neurotoxicity. FK506-induced cerebral infarctions have rarely...
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Relationship between Quality of Life and Nurse-led Bedside Symptom Evaluations in Patients with Chemotherapy-induced Peripheral Neuropathy

Yoo YS, Cho OH

  • KMID: 2069893
  • Asian Nurs Res.
  • 2014 Mar;8(1):36-41.
PURPOSE: This cross-sectional study aimed at determining the relationship between patient-reported quality of life (QOL) and nurse-led bedside evaluations of chemotherapy-induced peripheral neuropathy symptoms. METHODS: One hundred ninety-five patients treated at...
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Toxic Encephalopathy

Kim Y, Kim JW

  • KMID: 2317069
  • Saf Health Work.
  • 2012 Dec;3(4):243-256.
This article schematically reviews the clinical features, diagnostic approaches to, and toxicological implications of toxic encephalopathy. The review will focus on the most significant occupational causes of toxic encephalopathy. Chronic...
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Effects of Polychlorinated Biphenyls on the Development of Neuronal Cells in Growth Period; Structure-Activity Relationship

Do Y, Lee DK

Polychlorinated biphenyls (PCBs) are accumulated in our body through food chain and cause a variety of adverse health effects including neurotoxicities such as cognitive deficits and motor dysfunction. In particular,...
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Oculogyric Crisis Due to Metronidazole Toxic Encephalopathy

Lee SW, Kim H, Heo D, Park JH

Oculogyric crisis is an acute dystonia involving ocular muscles characterized by sustained conjugate upward or lateral deviation of the eyes. Metronidazole is a commonly used antimicrobial agent in treatment of...
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Serum markers and development of delayed neuropsychological sequelae after acute carbon monoxide poisoning: anion gap, lactate, osmolarity, S100B protein, and interleukin-6

Kim H, Choi S, Park E, Yoon E, Min Y, Lampotang

OBJECTIVE: Reliable biomarkers of delayed neuropsychological sequelae (DNS) after acute carbon monoxide (CO) poisoning are lacking. This study investigated the associations between potential serum markers and the development of DNS...
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Heptachlor induced nigral dopaminergic neuronal loss and Parkinsonism-like movement deficits in mice

Hong S, Hwang J, Kim JY, Shin KS, Kang SJ

Epidemiological studies have suggested an association between pesticide exposure and Parkinson's disease. In this study, we examined the neurotoxicity of an organochlorine pesticide, heptachlor, in vitro and in vivo. In...
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Metronidazole Induced Encephalopathy in a Patient with Brain Abscess

Bahn Y, Kim E, Park C, Park HC

Metronidazole is commonly used for brain abscess but is not well known for its neurotoxic complications. Metronidazole-induced encephalopathy (MIEP) is toxic encephalopathy associated with the use of metronidazole. We experienced...
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Occupational Neurological Disorders in Korea

Kim EA, Kang SK

The purpose of this article was to provide a literature review of occupational neurological disorders and related research in Korea, focusing on chemical hazards. We reviewed occupational neurological disorders investigated...
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