J Korean Neurol Assoc.
2018 Nov;36(4):322-324. 10.17340/jkna.2018.4.9.
Oculogyric Crisis Due to Metronidazole Toxic Encephalopathy
- Affiliations
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- 1Department of Neurology, Soonchunhyang University Bucheon Hospital, Bucheon, Korea. parkgene@schmc.ac.kr
- KMID: 2435843
- DOI: http://doi.org/10.17340/jkna.2018.4.9
Abstract
- Oculogyric crisis is an acute dystonia involving ocular muscles characterized by sustained conjugate upward or lateral deviation of the eyes. Metronidazole is a commonly used antimicrobial agent in treatment of anaerobic infections. However, its long-term use can cause toxic encephalopathy particularly in patients with hepatic dysfunction. Here, we describe a case of oculogyric crisis as a presenting manifestation of metronidazole-induced encephalopathy.
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