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Is primary sclerosing cholangitis with inflammatory bowel disease different between patients in the East and West?

Park YE

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Correlation of fecal calprotectin and patient-reported outcome measures in patients with ulcerative colitis

Kamat N, Vuyyuru SK, Kedia S, Sahu P, Kante B, Kumar P, Ranjan MK, Singh MK, Kumar S, Sachdev V, Makharia G, Ahuja V

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Endoscopic balloon dilations for strictures of rectum, ileocecal valve and duodenum in a patient with X-linked inhibitor of apoptosis deficiency: a case report

Otagiri S, Katsurada T, Sakurai K, Sugita J, Sakamoto N

X-linked inhibitor of apoptosis (XIAP) deficiency is a rare primary immunodeficiency and gastrointestinal (GI) lesions in XIAP deficiency are similar to Crohn’s disease. For patients with Crohn’s disease, endoscopic balloon...
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Update on the epidemiology of inflammatory bowel disease in Asia: where are we now?

Park SH

Inflammatory bowel disease (IBD) has become a global disease. As IBD is a chronic disease that can result in remarkable morbidity and disability, estimation and understanding the disease burden of...
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Artificial intelligence for endoscopy in inflammatory bowel disease

Takenaka K, Kawamoto A, Okamoto R, Watanabe M, Ohtsuka K

Inflammatory bowel disease (IBD), with its 2 subtypes, Crohn’s disease and ulcerative colitis, is a complex chronic condition. A precise definition of disease activity and appropriate drug management greatly improve...
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Addition of computed tomography chest increases the diagnosis rate in patients with suspected intestinal tuberculosis

Kedia S, Sharma R, Vuyyuru SK, Madhu D, Sahu P, Kante B, Das P, Goyal A, Madan K, Makharia G, Ahuja V

Background/Aims: Intestinal tuberculosis (ITB) is difficult to diagnose due to poor sensitivity of definitive diagnostic tests. ITB may be associated with concomitant pulmonary tuberculosis (PTB) which may remain undetected on...
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Fecal S100A12 is associated with future hospitalization and step-up of medical treatment in patients with Crohn’s disease in clinical remission: a pilot study

Lee SH, Hwang SW, Park SH, Yang DH, Byeon JS, Myung SJ, Yang SK, Ye BD

Background/Aims: Fecal S100A12 (FS) and serum S100A12 (SS) have been reported as novel biomarkers that accurately reflect intestinal inflammation. We evaluated if FS and SS in comparison to fecal calprotectin...
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SARS-CoV-2 vaccination for adult patients with inflammatory bowel disease: expert consensus statement by KASID

Lee YJ, Kim SE, Park YE, Chang JY, Song HJ, Kim DH, Yang YJ, Kim BC, Lee JG, Yang HC, Choi M, Myung SJ, The Clinical Practice Guideline Committee of the Korean Association for the Study of the Intestinal Diseases (KASID)

Coronavirus disease 2019 (COVID-19), caused by the novel coronavirus, is threatening global health worldwide with unprecedented contagiousness and severity. The best strategy to overcome COVID-19 is a vaccine. Various vaccines...
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Fecal microbiota transplantation for induction of remission, maintenance and rescue in patients with corticosteroid-dependent ulcerative colitis: a long-term follow-up real-world cohort study

Seth AK, Jain P

Background/Aims: To study role of fecal microbiota transplantation (FMT) in induction, maintenance, and rescue in patients with corticosteroid-dependent ulcerative colitis (CDUC). Methods: Patients with active CDUC received 3 fortnightly sessions...
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Drug therapy and monitoring for inflammatory bowel disease: a multinational questionnaire investigation in Asia

Cai C, Lu J, Lai L, Song D, Shen J, Tong J, Zheng Q, Wu K, Qian J, Ran Z

Background/Aims: The incidence and prevalence of inflammatory bowel disease (IBD) is rising in Asia recently. The study aimed to obtain a comprehensive understanding of the current status of drug therapy...
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Vedolizumab for perianal fistulizing Crohn’s disease: systematic review and meta-analysis

Ayoub F, Odenwald M, Micic D, Dalal SR, Pekow J, Cohen RD, Rubin DT, Sakuraba A

Background/Aims: Perianal fistulas are a debilitating manifestation of Crohn’s disease (CD). Despite the advent of anti-tumor necrosis factor (anti-TNF) therapy, the medical management of fistulizing CD continues to be challenged...
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Efficacy and tolerability of hyperbaric oxygen therapy in small bowel stricturing Crohn’s disease: a pilot study

Kante B, Sahu P, Kedia S, Vuyyuru SK, Soni K, Singhal M, Sharma R, Makharia G, Ahuja V

Background/Aims: Existing therapeutic options for complicated Crohn’s disease (CD) like biologics and surgery are limited by inadequate long-term efficacy, cost, and adverse effects. Tissue hypoxia is important in CD pathogenesis...
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Association of young age and male sex with primary sclerosing cholangitis in Taiwanese patients with inflammatory bowel disease

Weng MT, Shih IL, Tung CC, Leong YL, Shieh MJ, Wang CY, Wong JM, Ni YH, Wei SC

Background/Aims: Primary sclerosing cholangitis (PSC) is associated with inflammatory bowel disease (IBD). We aimed to evaluate the prevalence, clinical manifestation, and outcomes of PSC in Taiwanese patients with IBD. Methods:...
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Perspectives of East Asian patients and physicians on complementary and alternative medicine use for inflammatory bowel disease: results of a cross-sectional, multinational study

Kim ES, Tae CH, Jung SA, Park DI, Im JP, Eun CS, Yoon H, Jang BI, Ogata H, Fukuhara K, Hirai F, Ohtsuka K, Liu J, Cao Q, on behalf of the Clinical Research Committee of the Asian Organization for Crohn’s and Colitis

Background/Aims: Complementary and alternative medicine (CAM) is prevalent in East Asia. However, information on CAM in East Asian patients with inflammatory bowel disease (IBD) is scarce. We aimed to profile...
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One-year clinical efficacy and safety of indigo naturalis for active ulcerative colitis: a real-world prospective study

Matsuno Y, Torisu T, Umeno J, Shibata H, Hirano A, Fuyuno Y, Okamoto Y, Fujioka S, Kawasaki K, Moriyama T, Nagasue T, Zeze K, Hirakawa Y, Kawatoko S, Koga Y, Oda Y, Esaki M, Kitazono T

Background/Aims: Recent studies suggested a favorable effect of indigo naturalis (IN) in inducing remission for refractory ulcerative colitis (UC), however, the maintenance effect of IN for patients with UC remains...
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