- Comparison of Bone Marrow Stromal Cells with Fibroblasts in Wound Healing Accelerating Growth Factor Secretion
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Kim SH, Han SK, Yoon TH, Kim WK
- KMID: 2120051
- J Korean Soc Plast Reconstr Surg.
- 2006 Jan;33(1):1-4.
Cryopreserved fibroblast implants represent a major advancement for healing of chronic wounds. Bone marrow stromal cells, which include the mesenchymal stem cells, have a low immunity-assisted rejection and are capable... -
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- Antibody Response of Mouse Splenocytes Using Mixture of Supernatants of Thymocytes, Adherent and Non-adherent Splenocytes: In-vitro Immunization-II
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Kim D, Noh GW, Kim DH, Kwon OH
- KMID: 1421475
- J Korean Med Sci.
- 1990 Mar;5(1):25-31.
- doi: 10.3346/jkms.1990.5.1.25
We adapted one of the in-vitro immunization methods to induce antibody responses and confirmed the success of the immunization by enzyme-linked immunosorbent assay (ELISA) without hybridization. We have previously reported... -
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- Cytokine delivery and tissue engineering
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Lee SJ
- KMID: 1114559
- Yonsei Med J.
- 2000 Dec;41(6):704-719.
- doi: 10.3349/ymj.2000.41.6.704
Tissue engineering has been applied to various tissues, and particularly significant progress has been made in the areas of skin, cartilage, and bone regeneration. Inclusion of bioactive factors into the... -
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- Growth promotion of HepG2 hepatoma cells by antisense-mediated knockdown of glypican-3 is independent of insulin-like growth factor 2 signaling
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Sung YK, Hwang SY, Farooq M, Kim JC, Kim MK
- KMID: 1109313
- Exp Mol Med.
- 2003 Aug;35(4):257-262.
Glypican-3 (GPC3) encodes a cell-surface heparan-sulfate proteoglycan and its expression is frequently silenced in ovarian cancer, mesotheliomas, and breast cancer cell lines and ectopic expression of GPC3 inhibited the growth... -
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- Induction of proliferation in resting B-cells by a factor released by activated mouse spleen cells
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Puri N, Saxena RK
- KMID: 755009
- Exp Mol Med.
- 1998 Dec;30(4):199-204.
Mouse spleen cells activated in a mixed lymphocyte reaction release a soluble factor, which induces a significant proliferative response in fresh mouse spleen cells. This proliferation inducing factor (PIF) was... -
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- The Effect of Platelet-Rich Plasma on Survival of the Composite Graft and the Proper Time of Injection in a Rabbit Ear Composite Graft Model
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Choi HN, Han YS, Kim SR, Kim HK, Kim H, Park JH
- KMID: 2267613
- Arch Plast Surg.
- 2014 Nov;41(6):647-653.
- doi: 10.5999/aps.2014.41.6.647
BACKGROUND: Administration of growth factors has been associated with increased viability of composite grafts greater than 1-cm in diameter. Platelet-rich plasma (PRP) contains many of the growth factors studied. In... -
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- Short-term Morphological and Growth Factor Changes in Rat Bladders Augmented with a Porcine Small Intestinal Submucosa
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Byun SS, Kim JH, Oh JE, Kim HH, Lee ES, Lee CW
- KMID: 2293339
- Korean J Urol.
- 2003 May;44(5):473-480.
PURPOSE: This study was performed to investigate the short-term changes in the morphology and growth factors after the augment of rat bladders with a porcine small intestinal submucosa (SIS). MATERIALS AND... -
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- Ideal concentration of growth factors in rabbit's flexor tendon culture
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Kang HJ, Kang ES
- KMID: 1099875
- Yonsei Med J.
- 1999 Feb;40(1):26-29.
- doi: 10.3349/ymj.1999.40.1.26
Growth factors have the ability to stimulate matrix synthesis and cell proliferation in rabbit flexor tendon. Maximal stimulation effects of growth factors have a wide variation. It depends... -
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- Cellular signaling in tissue regeneration
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Kim WJ
- KMID: 1114558
- Yonsei Med J.
- 2000 Dec;41(6):692-703.
- doi: 10.3349/ymj.2000.41.6.692
With recent progress in stem cell-based research, there has been tremendous interest in stem cell-based tissue regeneration. Stem cells can be differentiated into specialized cells/tissues by growth factors and cytokines.... -
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- Tissue restoration, tissue engineering and regenerative medicine
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Suh H
- KMID: 1114556
- Yonsei Med J.
- 2000 Dec;41(6):681-684.
- doi: 10.3349/ymj.2000.41.6.681
Recently, thanks to the rapid progress of new technologies in cell modulation, extracellular matrix fabrication and synthetic polymers mimicking bodily structures, the self-regeneration of bodily defects by host tissue has... -
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- Effect of growth factors on the expression of proto-oncogenes c-fos and c-myc in FRTL-5 cell line
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Yoon HY, Oh SK, Yi KH, Cho BY, Koh CS
- KMID: 1054338
- J Korean Med Sci.
- 1995 Jun;10(3):155-163.
- doi: 10.3346/jkms.1995.10.3.155
This study was performed to prove the hypothesis that oncogene expressions would have the same patterns with those of cellular growth to growth factors in FRTL-5 cells. Ribonucleic acids of... -
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- Angiotensin II stimulates proliferation of adventitial fibroblasts cultured from rat aortic explants
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Kim DK, Huh JE, Lee SH, Hong KP, Park JE, Seo JD, Lee WR
- KMID: 646015
- J Korean Med Sci.
- 1999 Oct;14(5):487-496.
- doi: 10.3346/jkms.1999.14.5.487
It has been proposed that the local renin-angiotensin system is activated in the adventitia after vascular injury. However, the physiological role of Angiotensin II (Ang II) in the adventitia has... -
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- DNA Methylation Patterns of Ulcer-Healing Genes Associated with the Normal Gastric Mucosa of Gastric Cancers
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Hong SJ, Oh JH, Jung YC, Kim YH, Kim SJ, Kang SJ, Seo EJ, Choi SW, Kang MI, Rhyu MG
- KMID: 1778036
- J Korean Med Sci.
- 2010 Mar;25(3):405-417.
- doi: 10.3346/jkms.2010.25.3.405
Recent evidence suggests that gastric mucosal injury induces adaptive changes in DNA methylation. In this study, the methylation status of the key tissue-specific genes in normal gastric mucosa of healthy... -
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- The fetal wound healing: a review
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Roh TS, Rah DK, Park BY
- KMID: 720677
- Yonsei Med J.
- 2001 Dec;42(6):630-633.
- doi: 10.3349/ymj.2001.42.6.630
Fetal wound healing has drawn the attention of many researchers from diverse background and specialties. Fetal wound healing is unique and differs from postnatal healing in that fetal skin wounds... -
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- Angiogenesis and Mineralization During Distraction Osteogenesis
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Choi IH, Chung CY, Cho TJ, Yoo WJ
- KMID: 1109748
- J Korean Med Sci.
- 2002 Aug;17(4):435-447.
- doi: 10.3346/jkms.2002.17.4.435
Distraction osteogenesis is currently a standard method of bone lengthening. It is a viable method for the treatment of short extremities as well as extensive bone defects, because large amounts... -
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- Oxygen-Dependent and -Independent Regulation of HIF-1alpha
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Chun YS, Kim MS, Park JW
- KMID: 1127245
- J Korean Med Sci.
- 2002 Oct;17(5):581-588.
- doi: 10.3346/jkms.2002.17.5.581
Hypoxia-inducible factor-1 (HIF-1) is composed of HIF-1alpha and HIF-1beta, and is a master regulator of oxygen homeostasis, playing critical roles in physiological and pathological processes. Normally, the formation and... -
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- Effect of porcine bone morphogenetic protein on healing of bone defect in the rabbit radius
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Kim NH, Yang KH, Lee HM, Oh SH
- KMID: 1117765
- Yonsei Med J.
- 1992 Mar;33(1):54-63.
- doi: 10.3349/ymj.1992.33.1.54
Segmental long bone defects due to infection or trauma is a difficult problem to manage in patients. We studied the effect of porcine bone morphogenetic protein (pBMP) on healing of... -
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- Hypoxia-inducible factor (HIF-1)alpha: its protein stability and biological functions
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Lee JW, Bae SH, Jeong JW, Kim SH, Kim KW
- KMID: 755659
- Exp Mol Med.
- 2004 Feb;36(1):1-12.
Hypoxia-inducible factor (HIF-1) is an oxygen-dependent transcriptional activator, which plays crucial roles in the angiogenesis of tumors and mammalian development. HIF-1 consists of a constitutively expressed HIF-1beta subunit and one... -
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- Chemokines, osteopontin, ICAM-1 gene expression in cultured rat mesangial cells
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Lee SK, Park JY, Chung SJ, Yang WS, Kim SB, Park SK, Park JS
- KMID: 1064964
- J Korean Med Sci.
- 1998 Apr;13(2):165-170.
- doi: 10.3346/jkms.1998.13.2.165
To investigate whether MCP-1, CINC, RANTES, osteopontin and ICAM-1 mRNA could be induced in cultured rat mesangial cells by interleukin-1beta(IL-1beta), tumor necrosis factor-alpha (TNF-alpha) and lipopolysaccharide (LPS), and whether ... -
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- Effects of interleukin-10 on chemokine KC gene expression by mouse peritoneal macrophages in response to Candida albicans
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Kim HS, Shin DH, Kim SK
- KMID: 646014
- J Korean Med Sci.
- 1999 Oct;14(5):480-486.
- doi: 10.3346/jkms.1999.14.5.480
Chemokine KC has been considered to be a murine homologue of human GRO/MGSA and was identified as chemoattractant for monocytes and neutrophils. This study examined the expression of KC mRNA... -
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