Korean J Pediatr Infect Dis.  2005 Nov;12(2):157-165. 10.14776/kjpid.2005.12.2.157.

The Bacterial Colonization of Burn Wound and the Changes of Antibiotic Susceptibility in Childhood Burn (January, 1999~December, 2002)

• Kim JM
• Lee SY
• Kim YH
• Shin EW
• Oh PS
• Kim KN
• Lee KM
• Oh SJ

• KMID: 2440010
• DOI: http://doi.org/10.14776/kjpid.2005.12.2.157

Abstract

PURPOSE
Children occupy a large proportion of burn victims. So we want to aid to pediatric burn care through the understanding of the bacterial distribution in burn wounds and antibiotic susceptibility against isolated microorganisms from burn wounds.
METHODS
We analysed the medical records of 213 pediatric burn patients(0~15 years), 406 samples that grew bacteria in burn wound sites.
RESULTS
Of the total 213 patients, male were 59.6% and female were 40.4%. Scalding burn was the most common(78.4%), flame burn was the second(16.4%). Pathogens were isolated in 406 samples. The most common was Pseudomonas aeruginosa(58.1%). Next were Enterococcus species, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus species, Acinetobacter species. P. aeruginosa was resistant to trimethoprim-sulfamethoxazole in 100%, cephalothin in 98.1%, ampicillin-sulbactam in 96.2%, ampicillin in 95.3%, ceftriaxone in 95.2%, tobramycin in 93.7%, cefoperazone in 68.9%, ceftazidime in 67.7%. Enterococcus species were resistant to tetracycline in 63.9%, streptomycin in 45.5%, gentamicin in 36.1%, penicillin G in 13.7%. S. aureus was resistant to gentamicin in 89.7%, tetracycline in 86.2%, ciprofloxacin in 86.2%, penicillin G in 84.3%, oxacillin in 78.4%, erythromycin in 76.5%. Acinetobacter species were resistant to ampicillin-sulbactam in 100%, gentamicin in 85.7%, ampicillin in 83.3%, piperacillin in 61.5%.
CONCLUSION
P. aeruginosa was highly resistant to drugs like cefoperazone in 68.9%, ceftazidime 67.7%. S. aureus was highly resistant to penicillin G in 84.3%, oxacillin in 25.9%, but none to vancomycin in 0%, teicoplanin in 2.2%. According to the study, Acinetobacter species turned out to be multi-resistant strains, so careful attention must be paid to the choice of antibiotics.

Keyword

Burn wound; Bacterial colonization; Antibiotic susceptibility

MeSH Terms

Acinetobacter
Ampicillin
Anti-Bacterial Agents
Bacteria
Burns*
Cefoperazone
Ceftazidime
Ceftriaxone
Cephalothin
Child
Ciprofloxacin
Colon*
Enterococcus
Erythromycin
Female
Gentamicins
Humans
Male
Medical Records
Oxacillin
Penicillin G
Piperacillin
Pseudomonas
Staphylococcus aureus
Staphylococcus epidermidis
Streptococcus
Streptomycin
Teicoplanin
Tetracycline
Tobramycin
Trimethoprim, Sulfamethoxazole Drug Combination
Vancomycin
Wounds and Injuries*
Ampicillin
Anti-Bacterial Agents
Cefoperazone
Ceftazidime
Ceftriaxone
Cephalothin
Ciprofloxacin
Erythromycin
Gentamicins
Oxacillin
Penicillin G
Piperacillin
Streptomycin
Teicoplanin
Tetracycline
Tobramycin
Trimethoprim, Sulfamethoxazole Drug Combination
Vancomycin