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Effects of Indoor Air Purifiers on Children with Asthma

Lee GH, Kim JH, Kim S, Lee S, Lim DH

PURPOSE: To evaluate the effects of air purifiers on the concentrations of indoor air pollutants and on asthma control in children. MATERIALS AND METHODS: In this randomized crossover trial, daily use...
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Occurrence of infections in schoolchildren subsequent to supplementation with vitamin D-calcium or zinc: a randomized, double-blind, placebo-controlled trial

Mandlik R, Mughal Z, Khadilkar , Chiplonkar S, Ekbote V, Kajale N, Patwardhan V, Padidela R, Khadilkar

BACKGROUND/OBJECTIVES: Vitamin D and zinc are recognized for their roles in immune-modulation, and their deficiencies are suggested to be important risk factors for childhood infections. This study, therefore, undertook to...
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Analysis of Adult Patients with Tinea Capitis in Southeastern Korea

Lee HJ, Kim JY, Park KD, Jang YH, Lee SJ, Bang YJ, Jun JB, Lee WJ

BACKGROUND: Tinea capitis is a cutaneous infection of dermatophytes and predominant in children. Although tinea capitis in Korea is controlled by oral antifungal medications and concerted public health initiatives, it's...
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Prediction of dental caries in 12-year-old children using machine-learning algorithms

Yang YH, Kim JS, Jeong SH

OBJECTIVES: The decayed-missing-filled (DMFT) index is a representative oral health indicator. Prediction of DMFT index is an important basis for the development of public oral health care projects and strategies...
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The financial estimation of fluoride application coverage for children and adolescents

Jeon JE, Jung SH, Han DH, Lee SR, Ryu JI

OBJECTIVES: This study aimed to estimate the financial budget of fluoride application in the National Health Insurance. METHODS: The amount of fluoride application was calculated by using the sealant rate (utilization...
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Blood Pressure Curve for Children Less than 10 Years of Age: Findings from the Ewha Birth and Growth Cohort Study

Lee HA, Park B, Park EA, Cho SJ, Kim HS, Choi EJ, Kim NE, Park H

BACKGROUND: Routine blood pressure (BP) measurement is recommended to begin at 3 years of age, but there are no national BP reference values for Korean children less than 7 years...
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Associations of Plasma Neutrophil Gelatinase-associated Lipocalin, Anemia, and Renal Scarring in Children with Febrile Urinary Tract Infections

Lee JH, Yim HE, Yoo KH

BACKGROUND: Neutrophil gelatinase-associated lipocalin (NGAL), a bacteriostatic agent, is known to inhibit erythropoiesis leading to anemia. We aimed to investigate the associations of NGAL, anemia, and renal scarring in children...
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First Pediatric Case of Coronavirus Disease 2019 in Korea

Park JY, Han MS, Park KU, Kim JY, Choi EH

The large outbreak of coronavirus disease 2019 (COVID-19) that started in Wuhan, China has now spread to many countries worldwide. Current epidemiologic knowledge suggests that relatively few cases are seen...
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External Validation of a Pharmacokinetic Model of Propofol for Target-Controlled Infusion in Children under Two Years Old

Ji SH, Lee JH, Cho JY, Kim HS, Jang YE, Kim EH, Kim JT, Kim HS

BACKGROUND: Previously, a linked pharmacokinetic-pharmacodynamic model (the Kim model) of propofol with concurrent infusion of remifentanil was developed for children aged 2–12 years. There are few options for pharmacokinetic-pharmacodynamic model...
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Acute Leukemia Relapse Presenting as Recurrent Involvement of the Optic Nerve

Lee SY, Yoon JH, Chung SA

PURPOSE: To report two cases with recurrent involvement of the optic nerve as the initial sign of acute leukemic relapse. CASE SUMMARY: An 8-year-old male with acute lymphoblastic leukemia on the...
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Availability of Cycloplegic Refraction in Children and Adolescents

Kim SH, Lee YC

PURPOSE: To compare non-cycloplegic and cycloplegic refractive errors and evaluate the utility of cycloplegia in Korean children and young adolescents. METHODS: An anterospective study including 406 outpatients was conducted from September...
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Successful Treatment with Rituximab and Immunoadsorption for an Auto-Antibody Induced Bile Salt Export Pump Deficiency in a Liver Transplanted Patient

Quintero J, Juamperez , Gonzales E, Julio E, Mercadal-Hally M, Collado-Hilly M, Marín-Sánchez A, Charco R

We present an 8 years old girl who was diagnosed at 6 months of age of Progressive Familial Intrahepatic Cholestasis type 2. Although liver transplantation (LT) was classically considered curative...
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Determinants of Circulating Soluble Leptin Receptor and Free Leptin Index in Indonesian Pre-Pubertal Obese Male Children: A Preliminary Cross-Sectional Study

Hendarto A, Nagrani DG, Meiliana A, Sastroasmoro S, Sjarif DR

PURPOSE: This study aimed to investigate the clinical and metabolic determinants of circulating soluble leptin receptor (CSLR) and free leptin index (FLI) in pre-pubertal obese male children. METHODS: We conducted a...
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Cow's Milk-Related Symptom Score in Presumed Healthy Polish Infants Aged 0–6 Months

Bigorajska K, Filipiak Z, Winiarska , Adamiec A, Trent B, Vandenplas Y, Ruszczyński M, Szajewska

PURPOSE: The Cow's Milk-related Symptom Score (CoMiSSâ„¢), which considers crying, regurgitation, stools, skin and respiratory symptoms, was developed as an awareness tool for evaluating cow's milk-related symptoms. The scoring ranges...
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Liver Involvement in Children with Alpha-1 Antitrypsin Deficiency: A Multicenter Study

Cakir M, Sag E, Islek A, Baran M, Tumgor G, Aydogdu S

PURPOSE: Alpha-1 antitrypsin deficiency (A1ATD) in one of the most common genetic causes of liver disease in children. We aimed to analyze the clinical characteristics and outcomes of patients with...
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Does the Oral-Anal Transit Test Correlate with Colonic Manometry Findings in Children with Refractory Constipation?

Dranove J, Fleishman , Reddy S, Teich S

PURPOSE: The Oral-anal Transit Test (OTT) is a simple method of obtaining information about colonic transit. We aim to assess the correlation of OTT with the neuromuscular integrity of the...
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Effect of a Gluten Free Diet on Hepatitis B Surface Antibody Concentration in Previously Immunized Pediatric Celiac Patients

Zifman E, Zevit N, Heshin-Bekenstein M, Turner D, Shamir R, Silbermintz A

PURPOSE: To evaluate the effect of gluten-free diet (GFD) on hepatitis B surface antibody (HBsAb) concentrations among previously immunized pediatric celiac disease (CD) subjects. METHODS: We retrospectively evaluated pediatric CD subjects...
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Long-Term Efficacy of Anti-Tumor Necrosis Factor Agents in Pediatric Luminal Crohn's Disease: A Systematic Review of Real-World Evidence Studies

van Rheenen H, van Rheenen PF

PURPOSE: To determine the long-term efficacy of the anti-tumor necrosis factor (TNF) agents, infliximab (IFX) and adalimumab (ADA), in pediatric luminal Crohn's disease (CD) by performing a systematic literature review. METHODS:...
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The role of antibiotic prophylaxis in mild to moderate isolated hydronephrosis detected in antenatal screening

Rianthavorn P, Phithaklimnuwong S

PURPOSE: To determine whether continuous antibiotic prophylaxis (CAP) could prevent urinary tract infection (UTI) in mild to moderate antenatal isolated hydronephrosis (IH), characterized by hydronephrosis without ureter and bladder abnormalities,...
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Signal Detection of Adverse Events Following Pneumococcal Vaccines from the Korea Adverse Event Reporting System Database, 2005–2016

Kim KS, Oh IS, Kim HJ, Song I, Park MS, Shin JY

PURPOSE: We aimed to analyze the surveillance reports of adverse events (AEs) due to different types of pneumococcal vaccines, in addition to detecting and validating signals of pneumococcal vaccines by...
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