Difference in Bacteriology and Antibiotics Resistance with the Change of Burn Wound Dressing

Woo, Go Woon; Yu, Kyung Tag; Han, Hye Jung; Moon, Jae Hwan

Abstract

PURPOSE
This study aims to analyse the difference in bacteriology and antibiotics resistance on colonization of burn wound by the change of burn wound dressing.
METHODS
A retrospective review of all medical records of patients admitted with burns to the burn center of the Hanil General Hospital in 2002 when the conservative wound dressing was managed and in 2009 when the advanced wound dressing was carried out. Patient demographics, extent and type of burn, mortality rates were reviewed. Isolation and identification of microorganisms was done using the standard procedure. Disc diffusion tests were performed for all the isolates for antimicrobial susceptibility.
RESULTS
A total of 456 patients in 2002 and a total of 208 patients in 2009 were admitted. Of them, 27 patients in 2002 (Group A) and 35 patients in 2009 (Group B) have the result of colonization on burn wound by surface swab culture after post admission day 7. Mean age was 43.59+/-3.64 (Group A), 49.46+/-2.79 (Group B). The sex ratio of the patients was 1:0.4 with 20 men and 7 women (Group A), 1:0.5 with 24 men and 11 women (Group B). The mean admission day was 61.46+/-12.02 (Group A), 61.62+/-7.55 (Group B). The average value of total body area burned was 32.30+/-4.43 (Group A), 10.40+/-1.73 (Group B). A total of 3 patients (Group A) has inhalation burn. Three patients (Group A) and one patient (Group B) died. The most common cause of burn was flame burn (59.3%) (Group A), scald burn (48.6%) (Group B). The frequency of resistant microorganisms causing colonization on burn wound was 44.44% (Group A), 22.86% (Group B).
CONCLUSION
In group managed with the conservative burn dressing, the resistant microorganisms and pathogens are more frequent than in the advanced burn dressing group. However there was no statistically significant. Ongoing data collection and reanalysis is required.