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The rates of major malformations after gestational exposure to isotretinoin: a systematic review and meta-analysis

Choi EJ, Kim N, Kwak HS, Han HJ, Chun KC, Kim YA, Koh JW, Han JY, Joo SH, Lee JS, Koren G

Objective Isotretinoin is among the most notorious human teratogens, documented originally as causing up to 30% of malformations. This systematic review and meta-analysis aimed to evaluate the rates of major...
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Multiple Enhanced Lesions in the Brain MRI of a Patient with COVID-19

Kang YM, Park NH, Seong MJ, Han HJ, Jung YH

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Successful management of systemic lupus erythematosus with levamisole in a Dachshund dog

Kim DH, Han HJ, Kim JH

A 5-year-old neutered female Dachshund dog presented with a 3-month history of hyperthermia, skin lesions, and shifting lameness. Based on physical examination, blood tests, urinalysis, and radiographs, the dog was...
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Delays in Intracerebral Hemorrhage Management Is Associated with Hematoma Expansion and Worse Outcomes: Changes in COVID-19 Era

Han HJ, Park KY, Kim J, Lee W, Lee YH, Jang CK, Cho KC, Park SK, Chung J, Kwon YS, Kim YB, Lee JW, Kim SY

Purpose: The coronavirus disease 2019 (COVID-19) pandemic disrupted the emergency medical care system worldwide. We analyzed the changes in the management of intracerebral hemorrhage (ICH) and compared the pre-COVID-19 and...
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Effect of Integrated Cognitive Intervention Therapy in Patients with Mild to Moderate Alzheimer's Disease

Jung YH, Lee S, Kim WJ, Lee JH, Kim MJ, Han HJ

Background and Purpose: The effect of the integrated program comprising cognitive training, art therapy, and music therapy has not been extensively studied in patients with Alzheimer's disease (AD). The present...
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A rare case of intramural patent ductus arteriosus in a dog: anatomic, histopathologic, and radiographic features

Kim JH, Kim SM, Kim JY, Han HJ

A 5-year-old dog was evaluated for a lethargy and respiratory distress. Radiograph revealed cardiomegaly with pleural effusion, and the dog died during a thoracocentesis. At necropsy, the descending aorta and...
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Application of epoxy putty external skeletal fixator for stabilization of tarsocrural arthrodesis in small dogs and cats

Moon JS, Lee JS, Han HJ

Two small-breed dogs and two cats, with an average body weight of 4.88 kg (range: 4.3–5.5 kg), suffered hindlimb lameness due to luxation with or without fractures of the tarsocrural...
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Usefulness of a Vascular Clipping System to Create an Arteriovenous Fistula

Lee JS, Nam KJ, Yoon SY, Lee KO, Han HJ, Cho SJ, Park JW, Song TJ

Purpose: The vascular clipping system (VCS) is beneficial as it is simple and easy to apply for microvascular suturing. Arteriovenous fistula (AVF) creation is a very basic standard technique of...
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First Case of TARDBP-Related Amyotrophic Lateral Sclerosis in Korea

Han HJ, Park HJ, Yun U, Choi YC

No abstract available.
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Reliability and Validity of a Short Form of the Korean Dementia Screening Questionnaire-Cognition

Kim A, Kim S, Park KW, Park KH, Youn YC, Lee DW, Lee JY, Lee JH, Jeong JH, Choi SH, Han HJ, Kim S, Na S, Park M, Yim HW, Yang DW

BACKGROUND AND PURPOSE: We aimed to determine the reliability and validity of a short form of the Korean Dementia Screening Questionnaire-Cognition (KDSQ-C) as a screening tool for cognitive dysfunction. METHODS: This...
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Methicillin-resistant Staphylococcus aureus screening is important for surgeons

Hyun IK, Park PJ, Park D, Choi SB, Han HJ, Song TJ, Jung CW, Kim WB

BACKGROUNDS/AIMS: Perioperative surgical site infection (SSI) remains a morbid complication even in successful surgical procedures. We encountered an unusual experience of a methicillin-resistant Staphylococcus aureus (MRSA)-related SSI outbreak in our...
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Internet of Things-Based Behavioral Intervention for Older Adults with Major Depressive Disorder: Preliminary Study

Han HJ, Hong CH, Kim JH, Roh HW, Son SJ

OBJECTIVE: To assess the effectiveness of Internet of Things (IoT)-based behavioral intervention for reducing depressive symptom of older adults with major depressive disorder. METHODS: A 12-week randomized cross-over controlled study was...
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A Comparative Evaluation of the KDSQ-C, AD8, and SMCQ as a Cognitive Screening Test to Be Used in National Medical Check-ups in Korea

Kim A, Kim S, Park KW, Park KH, Youn YC, Lee DW, Lee JY, Lee JH, Jeong JH, Choi SH, Han HJ, Kim S, Na S, Park M, Yim HW, Yang DW

BACKGROUND: Korea has a periodic general health check-up program that uses the Korean Dementia Screening Questionnaire-Cognition (KDSQ-C) as a cognitive dysfunction screening tool. The Alzheimer Disease 8 (AD8) and Subjective...
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Role of HIF1α Regulatory Factors in Stem Cells

Lee HJ, Jung YH, Choi GE, Kim JS, Chae CW, Han HJ

Hypoxia-inducible factor 1 (HIF1) is a master transcription factor that induces the transcription of genes involved in the metabolism and behavior of stem cells. HIF1-mediated adaptation to hypoxia is required...
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Mini-partial lateral corpectomy and hemilaminectomy for the treatment of heavily protruded thoracolumbar intervertebral disc in small dogs

Five paraplegic dogs were diagnosed with thoracolumbar intervertebral disc disease with more than 50% compression of spinal cord. Because the lesions were determined to be disc extrusion on magnetic resonance...
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A Comparison Study of Cilostazol and Aspirin on Changes in Volume of Cerebral Small Vessel Disease White Matter Changes: Protocol of a Multicenter, Randomized Controlled Trial

Han HJ, Kim BC, Youn YC, Jeong JH, Kim JH, Lee JH, Park KH, Park KW, Kim EJ, Oh MS, Shim YS, Park HY, Yoon B, Yoon SJ, Cho SJ, Park KC, Na DL, Park SA, Lee JM, Choi SH

BACKGROUND AND PURPOSE: Cerebral small vessel disease (CSVD) is the most common cause of vascular dementia and a major contributor to mixed dementia. CSVD is characterized by progressive cerebral white...
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Status Epilepticus in a Patient with Extrapontine Myelinolysis

Jang K, Woo N, Lee H, Kim D, Lyou HJ, Han HJ, Kim GS

Extrapontine myelinolysis is a demyelinating disorder usually caused by rapid correction of chronic hyponatremia. We present an 82-year-old female patient with general weakness, and severe hyponatremia (103 mEq/L) which was...
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Validation of Korean Version of Coma Recovery Scale-Revised (K-CRSR)

Han HJ, Kim EJ, Lee HJ, Pyun SB, Joa KL, Jung HY

OBJECTIVE: To determine the validity and reliability of the Korean version of the Coma Recovery Scale-Revised (K-CRSR) for evaluation of patients with a severe brain lesion. METHODS: With permission from Giacino,...
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Murine γδ T Cells Render B Cells Refractory to Commitment of IgA Isotype Switching

Han HJ, Jang YS, Seo GY, Park SG, Kang SG, Yoon SI, Ko HJ, Lee GS, Kim PH

γδ T cells are abundant in the gut mucosa and play an important role in adaptive immunity as well as innate immunity. Although γδ T cells are supposed to be...
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Age-Specific Cutoff Scores on a T1-Weighted Axial Medial Temporal-Lobe Atrophy Visual Rating Scale in Alzheimer's Disease Using Clinical Research Center for Dementia of South Korea Data

Choi GS, Kim GH, Choi JH, Hwang J, Kwon E, Lee SA, Kong KA, Kang HJ, Yoon B, Kim BC, Yang DW, Na DL, Kim EJ, Na HR, Han HJ, Lee JH, Kim JH, Lee KY, Park KH, Park KW, Kim S, Han SH, Kim SY, Yoon SJ, Moon SY, Youn YC, Choi SH, Jeong JH

BACKGROUND AND PURPOSE: Visual assessment of medial temporal-lobe atrophy (MTA) has been quick, reliable, and easy to apply in routine clinical practice. However, one of the limitations in visual assessments...
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