J Korean Burn Soc.  2011 Jun;14(1):30-34.

Antimicrobial Central Venous Catheter Dose Not Reduce Catheter-related Bacteremia in Major Burn Injured Patients

• Jang YH
• Son YH
• Kim SK
• Park JM
• Lee MY

Abstract

PURPOSE
We previously reported that antimicrobial central venous catheter (CVC) reduced catheter colonization in major burn patients. In this study, we investigated whether antimicrobial CVC could reduce catheter-related blood stream infection (CRBSI) in major burn patients.
METHODS
Burn patients with over 20% of total body surface area were randomly assigned to undergo catheterization with standard CVC (STD group, n=50) or antimicrobial Vantex(R) CVC (VTX group, n=50). Upon removal of CVC, bacterial cultures for wound, catheter tip, and blood were performed.
RESULTS
Colonization rate was significantly decreased in VTX group (42%) compared to STD group (64%) (P<0.05). Colonization rate was higher in the case of the distance between the catheterization and burn wound was less than 10 cm in STD group (P<0.05). However, there was no statistical difference in CRBSI rate between the two groups (P>0.05).
CONCLUSION
Even though the antimicrobial CVC could reduce the catheter colonization, the CRBSI rate was not reduced by antimicrobial CVC in major burn patients.

Keyword

Burn; Catheter-related infections; Sepsis

MeSH Terms

Bacteremia
Body Surface Area
Burns
Catheter-Related Infections
Catheterization
Catheters
Central Venous Catheters
Colon
Humans
Rivers
Sepsis