Korean J Phys Anthropol.
2018 Mar;31(1):19-26. 10.11637/kjpa.2018.31.1.19.
Alterations in Spontaneous Movement, Corticosterone, and Cytokines in Mice Exposed to 835 MHz Radiofrequency Radiation
- Affiliations
-
- 1Department of Nursing, Shinhan University, Korea.
- 2Department of Anatomy, Seoul National University College of Medicine, Korea.
- 3Department of Emergency Medicine, Pusan National University Yangsan Hospital, Korea.
- 4Department of Pharmacology, Dankook University College of Medicine, Korea.
- 5Department of Anatomy, Dankook University College of Medicine, Korea. mjukim99@dankook.ac.kr
- KMID: 2408314
- DOI: http://doi.org/10.11637/kjpa.2018.31.1.19
Abstract
- Although commercialization of mobile phones has raised much concerns about the effects of radiofrequency radiation on the human body, few experimental studies have been conducted on the effects of radiofrequency radiation on physiological homeostasis, immune and inflammatory responses. Therefore, we presently investigated the effect of 835 MHz radiofrequency radiation on spontaneous wheel exercise, hormone and cytokines levels in the plasm of mice. Mice were divided into 4 groups as control, exercise, radiofrequency radiation, radiofrequency radiation & exercise group. The body weight, corticosterone and blood cytokine levels were checked for 10 weeks. Followed by the exposure to radiofrequency radiation for 6 hours a day, the more increase in body weight was observed in the radiofrequency radiation & exercise group than in the spontaneous exercise group. When the amount of spontaneous exercise was measured for 10 weeks, the amount of exercise was increased in the both control and spontaneous exercise group, while the amount of exercise was decreased in the radiofrequency radiation group. To determine whether the homeostasis, immune and inflammatory responses are indirectly affected by radiofrequency radiation exposure, IL-1β, IL-6, IL-12 (p70), TNF-α, IFNγ, and GM-CSF were measured by ELISA kit, respectively. As a result, the blood levels of IL-6, IL-12 (p70) and TNF-α in the spontaneous exercise group were higher than that of control group, and each cytokine levels in the radiofrequency radiation & exercise group were lower than that of control group. However, the corticosterone, IL-1β, IFNγ and GM-CSF didn't show statistically significant differences in all groups. It has been confirmed that exposure to high frequency electromagnetic waves for a long time can affect the amount of exercise, body weight, and some inflammatory cytokines such as IL-6, IL-12 (p70) and TNF-α.
MeSH Terms
-
Animals
Body Weight
Cell Phones
Corticosterone*
Cytokines*
Electromagnetic Radiation
Enzyme-Linked Immunosorbent Assay
Granulocyte-Macrophage Colony-Stimulating Factor
Homeostasis
Human Body
Interleukin-12
Interleukin-6
Mice*
Radiation Exposure
Corticosterone
Cytokines
Granulocyte-Macrophage Colony-Stimulating Factor
Interleukin-12
Interleukin-6
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Activation of autophagy at cerebral cortex and apoptosis at brainstem are differential responses to 835 MHz RF-EMF exposure
- The Effect of 835 MHz Radiofrequency Radiation Exposure on the Immunohistochemical Distribution of Calbindin D28k and Calretinin in the Mouse Cerebellar Cortex
- Prediction of the Exposure to 1763MHz Radiofrequency Radiation Based on Gene Expression Patterns
- Local exposure of 849 MHz and 1763 MHz radiofrequency radiation to mouse heads does not induce cell death or cell proliferation in brain
- Classification of Biological Effect of 1,763 MHz Radiofrequency Radiation Based on Gene Expression Profiles
