Sleep Med Psychophysiol.  2012 Jun;19(1):5-10.

The Effect of Sleep Loss on Energy and Metabolism

• Kang SG

Abstract

The release of hormones and the metabolism of human body are controlled by the circadian rhythm related to sleep-wake cycle. Growth hormone, prolactin, thyroid stimulating hormone, cortisol, glucose, and insulin-secretion rates fluctuate according to the sleep-wake cycle. In addition, sleep is related to the appetite regulation and carbohydrate and other energy metabolism. Hypocretin (orexin), an excitatory neuropeptide, regulates waking and diet intake, and the poor sleep increases diet intake. The short sleep duration increases one's body mass index and impairs the function of the endocrine and metabolism, causing increases in the risk of glucose intolerance and diabetes. The poor sleep quality and sleep disorders have similar impact on the metabolic function. In short, the sleep loss and the poor quality of sleep have a detrimental effect on the endocrine and energy metabolism. The improvement of sleep quality by the future research and appropriate clinical treatment would contribute to the decrease of the metabolic diseases such as diabetes.

Keyword

Sleep loss; Energy; Metabolism

MeSH Terms

Appetite Regulation
Body Mass Index
Circadian Rhythm
Diet
Energy Metabolism
Glucose
Glucose Intolerance
Growth Hormone
Human Body
Hydrocortisone
Intracellular Signaling Peptides and Proteins
Metabolic Diseases
Neuropeptides
Prolactin
Sleep Wake Disorders
Thyrotropin
Orexins
Glucose
Growth Hormone
Hydrocortisone
Intracellular Signaling Peptides and Proteins
Neuropeptides
Prolactin
Thyrotropin