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Leisure Time Physical Activity to Reduce Metabolic Syndrome Risk: A 10-Year Community-Based Prospective Study in Korea

Jo H, Kim JY, Jung MY, Ahn YS, Chang SJ, Koh SB

PURPOSE: Metabolic syndrome (MetS) is a major public health problem related to increased risks of cardiovascular disease and type 2 diabetes. We investigated whether recommended levels of leisure time physical...
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Association Between Trp64arg Polymorphism of the β3 adrenoreceptor Gene and Female Sex in Obese Turkish Children and Adolescents

Yılmaz R, Ateş O, Gül A, Kasap T, Özer S, Ensari E

PURPOSE: The β3-adrenergic receptor (ADRB3) is expressed in visceral adipose tissue and has been speculated to contribute to lipolysis, energy metabolism, and regulation of the metabolic rate. In this study,...
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Validity of the dietary reference intakes for determining energy requirements in older adults

Ndahimana , Go NY, Ishikawa-Takata K, Park J, Kim EK

BACKGROUND/OBJECTIVES: The objectives of this study were to evaluate the accuracy of the Dietary Reference Intakes (DRI) for estimating the energy requirements of older adults, and to develop and validate...
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Serum osteocalcin levels in overweight children

Oh SB, Lee WY, Nam HK, Rhie YJ, Lee KH

PURPOSE: Bone plays a role in glucose metabolism through the release of uncarboxylated osteocalcin into the systemic circulation. The identified novel roles for osteocalcin include increasing insulin secretion and sensitivity,...
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Evaluation of bioenergetic and mitochondrial function in liver transplantation

Martins RM, Teodoro JS, Furtado E, Rolo AP, Palmeira C, Tralhão J

BACKGROUND/AIMS: We measured changes in mitochondrial function and bioenergetics that occur during ischemia/reperfusion in fresh liver samples of patients undergoing liver transplantation. These variations correlated with markers of liver function...
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Sodium-Glucose Cotransporter 2 Inhibitors: Mechanisms of Action and Various Effects

Kim KS

The basic action mechanism of sodium-glucose cotransporter 2 (SGLT2) inhibitor is to lower the glucose burden by excreting the glucose filtered by the kidney into the urine. Although SGLT2 inhibitors...
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Effects of Multifactorial and Follow-up Programs Applying a Capacity Building Strategy: Focusing on Older Adults Living in a Urban-rural Complex Area

Han SY, Ko Y, Kim HR, Kim J

PURPOSE: The purpose of this study is to examine effects of a multifactorial program for preventing the frailty of older adults and effects of a follow-up program applying a capacity...
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Lack of Current Recommendations for Resuming Sexual Activity Following Spinal Surgery

Thomas CM, Levene HB

Patients are faced with many questions surrounding the after effects of the various surgical procedures and their ability to return to preoperative activities. While patients often question whether surgery would...
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Metformin, an Activator of AMPK, Promotes the Growth of Hair Follicles via the AMPK/β-catenin Signaling Pathway

Moon HR, Park KY, Kang HJ, Lee WJ, Won CH, Chang SE, Lee MW, Choi JH, Park GH

  • KMID: 2449198
  • Korean J Dermatol.
  • 2019 May;57(4):175-181.
BACKGROUND: AMP-activated protein kinase (AMPK) is a serine/threonine protein kinase that plays a pivotal role in the balance of cellular energy metabolism. Recent studies have reported that AMPK has numerous...
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Intermittent Fasting: a Promising Approach for Preventing Vascular Dementia

Yoon G, Song J

Vascular dementia is the most common neuropsychiatric syndrome and is characterized by synaptic dysfunction, neuroinflammation, and cognitive dysfunction. Vascular dementia is associated with various environmental, genetic, and lifestyle risk factors....
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Asthma and obesity: Is asthma a risk factor for obesity?

Kim JK, Yang JH

Many studies have shown that asthma and obesity are linked and affect each other. Although obesity is an important risk factor for asthma, it is controversial whether asthma is a...
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Dysfunctional Mitochondrial Bioenergetics and Synaptic Degeneration in Alzheimer Disease

Tang J, Oliveros A, Jang MH

Synapses are sites of high energy demand which are dependent on high levels of mitochondrial derived adenosine triphosphate. Mitochondria within synaptic structures are key for maintenance of functional neurotransmission and...
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Two Faces of White Adipose Tissue with Heterogeneous Adipogenic Progenitors

Hwang I, Kim JB

Chronic energy surplus increases body fat, leading to obesity. Since obesity is closely associated with most metabolic complications, pathophysiological roles of adipose tissue in obesity have been intensively studied. White...
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Relationship Between Performance Improvement in Activities of Daily Living and Energy Intake in Older Patients With Hip Fracture Undergoing Rehabilitation

Umezawa H, Kokura Y, Abe S, Suzuki C, Nishida A, Uchiyama Y, Maeda K, Wakabayashi H, Momosaki R

OBJECTIVE: To analyze whether sufficient energy intake (EI) improves performance of activities of daily living (ADL) in patients with hip fracture admitted to rehabilitation hospitals. The adequate amount of EI...
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Augmentation of Doppler Radar Data Using Generative Adversarial Network for Human Motion Analysis

Alnujaim I, Kim Y

OBJECTIVES: Human motion analysis can be applied to the diagnosis of musculoskeletal diseases, rehabilitation therapies, fall detection, and estimation of energy expenditure. To analyze human motion with micro-Doppler signatures measured...
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Validation of Dietary Reference Intakes for predicting energy requirements in elementary school-age children

Kim EK, Ndahimana , Ishikawa-Takata K, Lee S, Kim H, Lim K, Lee IS, Tanaka S, Kim YJ, Choi YJ, Ju MJ, Park J

BACKGROUND/OBJECTIVES: Dietary Reference Intakes (DRI) for energy are derived from total energy expenditure (TEE) measured using the doubly labelled water (DLW) method. The objective of this study was to assess...
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Validity of predictive equations for resting energy expenditure in Korean non-obese adults

Ndahimana , Choi YJ, Park JH, Ju MJ, Kim EK

BACKGROUND/OBJECTIVES: Indirect calorimetry is the gold-standard method for the measurement of resting energy expenditure. However, this method is time consuming, expensive, and requires highly trained personnel. To overcome these limitations,...
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Quercetin Upregulates Uncoupling Protein 1 in White/Brown Adipose Tissues through Sympathetic Stimulation

Choi H, Kim CS, Yu R

BACKGROUND: Uncoupling protein 1 (UCP1) plays an important role in increasing energy expenditure; thus, it is being considered as a new target for preventing obesity and metabolic complications. In this...
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The Effect of Circadian and Sleep Disruptions on Obesity Risk

Noh J

The prevalence of obesity continues to increase worldwide. Multiple risk factors and complex mechanisms are involved in the development and maintenance of obesity. Recently, emerging evidence has indicated that the...
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Inhibition of Serotonin Synthesis Induces Negative Hepatic Lipid Balance

Namkung J, Shong KE, Kim H, Oh CM, Park S, Kim H

BACKGROUND: Hepatic steatosis is caused by metabolic stress associated with a positive lipid balance, such as insulin resistance and obesity. Previously we have shown the anti-obesity effects of inhibiting serotonin...
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