J Obes Metab Syndr.  2018 Jun;27(2):78-83. 10.7570/jomes.2018.27.2.78.

The Effect of Circadian and Sleep Disruptions on Obesity Risk

Affiliations
  • 1Department of Internal Medicine, Inje University Ilsan Paik Hospital, Goyang, Korea. jhnoh@paik.ac.kr

Abstract

The prevalence of obesity continues to increase worldwide. Multiple risk factors and complex mechanisms are involved in the development and maintenance of obesity. Recently, emerging evidence has indicated that the circadian rhythm is important for regulating metabolism because the circadian system modulates energy metabolism and enhances certain energetic activities during day and night. Lifestyle also has a great impact on the circadian system. In addition to traditional risk factors, sleep and circadian disruptions are known modifiable risk factors for obesity and other metabolic disorders. This paper reviews recent evidence of relationships between energy metabolism and the circadian system and discusses how sleep disruption and circadian misalignment influence the development of obesity.

Keyword

Obesity; Circadian rhythm; Sleep wake disorders

MeSH Terms

Circadian Rhythm
Energy Metabolism
Life Style
Metabolism
Obesity*
Prevalence
Risk Factors
Sleep Wake Disorders
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