- Narcolepsy in Children
-
Seo WS
- KMID: 2317500
- Sleep Med Psychophysiol.
- 2011 Jun;18(1):17-22.
Childhood narcolepsy is one of the underdiagnosed diseases even the first symptoms often appear in childhood. Making diagnosis through history taking is not always easy because the symptoms of childhood... -
- CITED
-
- Close
- SHARE
-
- Close
- Current concepts of the podocyte in nephrotic syndrome
-
Ding WY, Saleem MA
- KMID: 1441573
- Kidney Res Clin Pract.
- 2012 Jun;31(2):87-93.
Nephrotic syndrome is a disorder of the glomerular filtration barrier, and central to the filtration mechanism of the glomerular filtration barrier is the podocyte. We are starting to better understand... -
- CITED
-
- Close
- SHARE
-
- Close
- Narcolepsy: Clinical Feature, Diagnosis and Treatment
-
Shin HB
- KMID: 2317492
- Sleep Med Psychophysiol.
- 2010 Dec;17(2):63-68.
Narcolepsy is a central neurologic system disease. It begins early in life with disabling symptoms including excessive daytime sleepiness, cataplexy, sleep paralysis, hypnagogic hallucination and nocturnal sleep fragmentation. Patient with... -
- CITED
-
- Close
- SHARE
-
- Close
- Can oliceridine (TRV130), an ideal novel µ receptor G protein pathway selective (µ-GPS) modulator, provide analgesia without opioid-related adverse reactions?
-
Ok HG, Kim SY, Lee SJ, Kim TK, Huh BK, Kim KH
- KMID: 2410828
- Korean J Pain.
- 2018 Apr;31(2):73-79.
- doi: 10.3344/kjp.2018.31.2.73
All drugs have both favorable therapeutic and untoward adverse effects. Conventional opioid analgesics possess both analgesia and adverse reactions, such as nausea, vomiting, and respiratory depression. The opioid ligand binds... -
- CITED
-
- Close
- SHARE
-
- Close
- Late-Onset Narcolepsy with Cataplexy Unresponsive to Intravenous High-Dose Immunoglobulin Treatment
-
Cho JW, Jung NY, Bae JW, Kim DJ, Lee JH, Kanbayashi T
- KMID: 2343436
- J Korean Neurol Assoc.
- 2012 Feb;30(1):57-59.
Narcolepsy with cataplexy (NC) is associated with hypocretin deficiency, and is thought to be an autoimmunity condition. The mean age at onset is estimated to be in the early 20s.... -
- CITED
-
- Close
- SHARE
-
- Close
- LGR5 and Downstream Intracellular Signaling Proteins Play Critical Roles in the Cell Proliferation of Neuroblastoma, Meningioma and Pituitary Adenoma
-
Hwang M, Han MH, Park HH, Choi H, Lee KY, Lee YJ, Kim JM, Cheong JH, Ryu JI, Min KW, Oh YH, Ko Y, Koh SH
- KMID: 2463717
- Exp Neurobiol.
- 2019 Oct;28(5):628-641.
- doi: 10.5607/en.2019.28.5.628
Leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5) has been reported to play critical roles in the proliferation of various cancer cells. However, the roles of LGR5 in brain tumors and... -
- CITED
-
- Close
- SHARE
-
- Close
- Polyubiquitin chain-dependent protein degradation in TRIM30 cytoplasmic bodies
-
Choi UY, Choi WY, Hur JY, Kim YJ
- KMID: 2070278
- Exp Mol Med.
- 2015 Apr;47(4):e159.
- doi: 10.1038/emm.2015.12
Viral infection induces numerous tripartite motif (TRIM) proteins to control antiviral immune signaling and viral replication. Particularly, SPRY-containing TRIM proteins are found only in vertebrates and they control target protein... -
- CITED
-
- Close
- SHARE
-
- Close
- The mutational landscape of hepatocellular carcinoma
-
Lee JS
- KMID: 2351021
- Clin Mol Hepatol.
- 2015 Sep;21(3):220-229.
- doi: 10.3350/cmh.2015.21.3.220
The development of hepatocellular carcinoma (HCC) is a complex process, and HCC arises from the accumulation of multiple genetic alterations leading to changes in the genomic landscape. Current advances in... -
- CITED
-
- Close
- SHARE
-
- Close
- Aralia cordata Extract Activates NF-κB and MAPK Signaling Pathways and Induces Pro-inflammatory Changes in RAW264.7 Macrophages
-
Seo DW, Cho YI, Yi YJ, Lee SM
- KMID: 2468022
- J Bacteriol Virol.
- 2019 Dec;49(4):153-161.
- doi: 10.4167/jbv.2019.49.4.153
Macrophages play essential roles in innate immune responses by producing various immune mediators. Therefore, modulating macrophage function is an attractive strategy to treat immune disorders. Aralia cordata var. continentalis (AC),... -
- CITED
-
- Close
- SHARE
-
- Close
- The Effect of Sleep Loss on Energy and Metabolism
-
Kang SG
- KMID: 2317512
- Sleep Med Psychophysiol.
- 2012 Jun;19(1):5-10.
The release of hormones and the metabolism of human body are controlled by the circadian rhythm related to sleep-wake cycle. Growth hormone, prolactin, thyroid stimulating hormone, cortisol, glucose, and insulin-secretion... -
- CITED
-
- Close
- SHARE
-
- Close
- Inhibitors of Apoptosis Proteins Expression and Their Prognostic Significance in Colorectal Carcinoma
-
Lee KH, Lee S, Lee HM, Back SC, Cho SB, Lee JH
- KMID: 2277504
- Korean J Pathol.
- 2011 Aug;45(4):397-405.
BACKGROUND: The expression of the inhibitor of apoptosis proteins (IAPs) family has not been fully investigated in colorectal carcinomas. This study investigated IAP expression in colorectal carcinomas and assessed their... -
- CITED
-
- Close
- SHARE
-
- Close
- RING Finger Proteins Are Involved in the Progression of Barrett Esophagus to Esophageal Adenocarcinoma: A Preliminary Study
-
Wang XW, Wei W, Wang WQ, Zhao XY, Guo H, Fang DC
- KMID: 2070058
- Gut Liver.
- 2014 Sep;8(5):487-494.
- doi: 10.5009/gnl13133
BACKGROUND/AIMS: To investigate the differential expression of RING finger (RNF) proteins in Barrett esophagus (BE) and esophageal adenocarcinoma (EAC). METHODS: The differential expression of RNFs in normal esophagus (NE), BE, and... -
- CITED
-
- Close
- SHARE
-
- Close
- Role of LPA and the Hippo pathway on apoptosis in salivary gland epithelial cells
-
Hwang SM, Jin M, Shin YH, Ki Choi S, Namkoong E, Kim M, Park MY, Park K
- KMID: 2155390
- Exp Mol Med.
- 2014 Dec;46(12):e125.
- doi: 10.1038/emm.2014.77
Lysophosphatidic acid (LPA) is a bioactive lysophospholipid involved in numerous physiological responses. However, the expression of LPA receptors and the role of the Hippo signaling pathway in epithelial cells have... -
- CITED
-
- Close
- SHARE
-
- Close
- Micropatterned grooves and acid-etching on titanium substrata alter viability and gene expression of adhered human gingival fibroblasts: A pilot study
-
Lee SW, Kim SY, Lee KW
- KMID: 2195660
- J Korean Acad Prosthodont.
- 2007 Jun;45(3):375-381.
STATEMENT OF PROBLEM: Prior to determining an optimal width of micropatterned grooves provided on titanium substrata, we have done a pilot study using surface topographies in combined microm and submicrom... -
- CITED
-
- Close
- SHARE
-
- Close
- The Changes of Slit Diaphragm Molecules After Using Sirolimus
-
Choi JY, Han GD, Kim YJ, Park YH
- KMID: 2196735
- J Korean Soc Pediatr Nephrol.
- 2010 Oct;14(2):143-153.
PURPOSE: Recently, massive proteinuria has been observed in some transplant patients after switching cyclosporine A (CsA) to sirolimus. To evaluate the pathogenesis of sirolimus-associated proteinuria, we investigated the early changes... -
- CITED
-
- Close
- SHARE
-
- Close
- Cyclooxygenase 2 in Gastric Carcinoma Is Expressed in Doublecortin- and CaM Kinase-Like-1-Positive Tuft Cells
-
Mutoh H, Sashikawa , Sakamoto H, Tateno T
- KMID: 2070061
- Gut Liver.
- 2014 Sep;8(5):508-518.
- doi: 10.5009/gnl13237
BACKGROUND/AIMS: Doublecortin and CaM kinase-like-1 (DCAMKL1) is a marker of stem cells expressed predominantly in the crypt base in the intestine. However, DCAMKL1-positive cells have been shown to be differentiated... -
- CITED
-
- Close
- SHARE
-
- Close
- Phosphoinositide 3-kinase (PI3K) as a New Therapeutic Target for Rheumatoid Arthritis
-
Kim HR
- KMID: 2223030
- J Rheum Dis.
- 2013 Apr;20(2):74-82.
- doi: 10.4078/jrd.2013.20.2.74
Dysregulated activation of immune and synovial cells and their reciprocal action play a key role in the pathogenesis of rheumatoid arthritis (RA). Various signal transduction molecules regulate cellular responses and... -
- CITED
-
- Close
- SHARE
-
- Close
- Molecules and their functions in autophagy
-
Pyo JO, Nah J, Jung YK
- KMID: 1120125
- Exp Mol Med.
- 2012 Feb;44(2):73-80.
- doi: 10.3858/emm.2012.44.2.029
Autophagy is a self-degradation system of cellular components through an autophagosomal-lysosomal pathway. Over the last 15 yr, yeast genetic screens led to the identification of a number of genes involved... -
- CITED
-
- Close
- SHARE
-
- Close
- Suppression of Heme Oxygenase-1 by Prostaglandin E2-Protein Kinase A-A-Kinase Anchoring Protein Signaling Is Central for Augmented Cyclooxygenase-2 Expression in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages
-
Lee JH, Jung NH, Lee BH, Kim SH, Jun JH
- KMID: 2260815
- Allergy Asthma Immunol Res.
- 2013 Sep;5(5):329-336.
- doi: 10.4168/aair.2013.5.5.329
PURPOSE: Prostaglandin (PG) E2 is an immunomodulatory lipid mediator generated mainly via the cyclooxygenase-2 (COX-2) pathway from arachidonic acid at sites of infection and inflammation. A positive feedback loop of... -
- CITED
-
- Close
- SHARE
-
- Close
- Nitric Oxide-mediated Relaxation by High K+ in Human Gastric Longitudinal Smooth Muscle
-
Kim YC, Choi W, Yun HY, Sung R, Yoo RY, Park SM, Yun SJ, Kim MJ, Song YJ, Xu WX, Lee SJ
- KMID: 2285428
- Korean J Physiol Pharmacol.
- 2011 Dec;15(6):405-413.
- doi: 10.4196/kjpp.2011.15.6.405
This study was designed to elucidate high-K+induced response of circular and longitudinal smooth muscle from human gastric corpus using isometric contraction. Contraction from circular and longitudinal muscle stripes of gastric... -
- CITED
-
- Close
- SHARE
-
- Close
