Restor Dent Endod.  2014 May;39(2):109-114.

Antibacterial properties of composite resins incorporating silver and zinc oxide nanoparticles on Streptococcus mutans and Lactobacillus

Affiliations
  • 1Dental Research Center, Department of Restorative Dentistry, Dental School, Hamadan University of Medical Sciences, Hamadan, Iran. zkhamverdi@yahoo.ca
  • 2Department of Oral Medicine, Dental School, Hamadan University of Medical Sciences, Hamadan, Iran.
  • 3Department of Endodontic, Dental School, Hamadan University of Medical Sciences, Hamadan, Iran.
  • 4Department of Microbiology, Dental School, Hamadan University of Medical Sciences, Hamadan, Iran.
  • 5Department of Restorative Dentistry, Dental School, Hamadan University of Medical Sciences, Hamadan, Iran.

Abstract


OBJECTIVES
Recurrent caries was partly ascribed to lack of antibacterial properties in composite resin. Silver and zinc nanoparticles are considered to be broad-spectrum antibacterial agents. The aim of the present study was to evaluate the antibacterial properties of composite resins containing 1% silver and zinc-oxide nanoparticles on Streptococcus mutans and Lactobacillus.
MATERIALS AND METHODS
Ninety discoid tablets containing 0%, 1% nano-silver and 1% nano zinc-oxide particles were prepared from flowable composite resin (n = 30). The antibacterial properties of composite resin discs were evaluated by direct contact test. Diluted solutions of Streptococcus mutans (PTCC 1683) and Lactobacillus (PTCC 1643) were prepared. 0.01 mL of each bacterial species was separately placed on the discs. The discs were transferred to liquid culture media and were incubated at 37degrees C for 8 hr. 0.01 mL of each solution was cultured on blood agar and the colonies were counted. Data was analyzed with Kruskall-Wallis and Mann-Whitney U tests.
RESULTS
Composites containing nano zinc-oxide particles or silver nanoparticles exhibited higher antibacterial activity against Streptococcus mutans and Lactobacillus compared to the control group (p < 0.05). The effect of zinc-oxide on Streptococcus mutans was significantly higher than that of silver (p < 0.05). There were no significant differences in the antibacterial activity against Lactobacillus between composites containing silver nanoparticles and those containing zinc-oxide nanoparticles.
CONCLUSIONS
Composite resins containing silver or zinc-oxide nanoparticles exhibited antibacterial activity against Streptococcus mutans and Lactobacillus.

Keyword

Anti-bacterial agents; Composite resin; Nanoparticles; Silver; Zinc oxide

MeSH Terms

Agar
Anti-Bacterial Agents
Composite Resins*
Culture Media
Lactobacillus*
Nanoparticles*
Silver*
Streptococcus mutans*
Streptococcus*
Tablets
Zinc Oxide*
Zinc*
Agar
Anti-Bacterial Agents
Composite Resins
Culture Media
Silver
Tablets
Zinc
Zinc Oxide
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