- A Single Arm, Phase II Study of Simvastatin Plus XELOX and Bevacizumab as First-Line Chemotherapy in Metastatic Colorectal Cancer Patients
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Kim Y, Kim TW, Han SW, Ahn JB, Kim ST, Lee J, Park JO, Park YS, Lim HY, Kang WK
- KMID: 2454304
- Cancer Res Treat.
- 2019 Jul;51(3):1128-1134.
- doi: 10.4143/crt.2018.379
PURPOSE: Simvastatin has demonstrated anti-tumor activity in preclinical studies via tumor cell senescence, apoptosis, and anti-angiogenesis. This phase II trial evaluated the efficacy and toxicity profile of conventional XELOX and... -
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- Comparison of pharmacokinetic characteristics of two Tegoprazan (CJ-12420) formulations in healthy male subjects
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Hwang JG, Yoo H, Lee JW, Song GS, Lee S, Kim MG
- KMID: 2457576
- Transl Clin Pharmacol.
- 2019 Jun;27(2):80-85.
- doi: 10.12793/tcp.2019.27.2.80
Proton-pump inhibitors (PPIs) are effectively used to treat acid-related diseases, including gastroesophageal reflux disease (GERD); however, many unmet medical needs still exist. As a new treatment option, potassium-competitive acid blockers... -
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- Elevation of Procalcitonin in an Adolescent Acetaminophen Intoxication
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Kim SE, Lee JB, Jin YH, Yoon JC, Jo SO, Jeong TO
- KMID: 2452742
- J Korean Soc Clin Toxicol.
- 2019 Jun;17(1):38-41.
- doi: 10.22537/jksct.2019.17.1.38
Procalcitonin (PCT) is commonly employed in medical practice as a diagnostic biomarker of bacterial infection and also as a monitoring biomarker for antimicrobial therapy. There have been a few published... -
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- The use of mobile computing devices in microsurgery
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Pafitanis , Hadjiandreou M, Miller R, Mason K, Theodorakopoulou E, Sadri A, Taylor K, Myers S
- KMID: 2446809
- Arch Plast Surg.
- 2019 Mar;46(2):102-107.
- doi: 10.5999/aps.2018.00150
Mobile computing devices (MCDs), such as smartphones and tablets, are revolutionizing medical practice. These devices are almost universally available and offer a multitude of capabilities, including online features, streaming capabilities,... -
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- The impacts of three-dimensional anatomical atlas on learning anatomy
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Park S, Kim Y, Park S, Shin JA
- KMID: 2442332
- Anat Cell Biol.
- 2019 Mar;52(1):76-81.
- doi: 10.5115/acb.2019.52.1.76
Gross anatomy has traditionally been the foundation of medical education. Medical students have learned the structure of the human body through dissection, lecture, and textbooks. As tablets and three-dimensional (3D)... -
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- Comparative Analysis of Prescription for Splitted Tablet using the HIRA-NPS (Health Insurance Review & Assessment Service-National Patient Sample)
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Kwon HJ, Jang KW, Ha D
- KMID: 2470460
- Korean J Clin Pharm.
- 2019 Dec;29(4):231-237.
- doi: 10.24304/kjcp.2019.29.4.231
OBJECTIVE: The aim of this study was to analyze the status of split tablet prescription in South Korea. METHODS: We conducted this analysis using 2016 National Patient Sample data from the... -
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- Effect of Commercial Effervescent Vitamin Tablets on Bovine Enamel
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Jeong MJ, Lee MH, Jeong SJ, Kim SJ, Ko MJ, Sim HW, Lee JY, Im AJ, Lim DS
- KMID: 2469742
- J Dent Hyg Sci.
- 2019 Dec;19(4):261-270.
- doi: 10.17135/jdhs.2019.19.4.261
BACKGROUND: In this study, four types of effervescent vitamins marketed in Korea were analyzed for their acidity and vitamin content. For this purpose, bovine teeth were immersed in vitamin, and... -
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- Characteristics of poisoning in younger children according to different forms of the drugs
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Jang M, Ko Y, Yang HW, Lee J
- KMID: 2469719
- Pediatr Emerg Med J.
- 2019 Dec;6(2):57-62.
- doi: 10.22470/pemj.2019.00108
PURPOSE: This study aimed to investigate the characteristics of poisoning drug ingested by younger children, and to compare the clinical outcome by drug forms. METHODS: This was a retrospective analysis based... -
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- Psychotic Symptoms of Hashimoto's Encephalopathy: A Diagnostic Challenge
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Savarimuthu MK, Tsheringla S, Mammen P
- KMID: 2438613
- J Korean Acad Child Adolesc Psychiatry.
- 2019 Jan;30(1):42-44.
- doi: 10.5765/jkacap.180022
Hashimoto's encephalopathy (HE) is a rare and underdiagnosed neuropsychiatric illness. We present the case of a 17-year-old girl who was admitted to a tertiary-care psychiatric center with acute onset psychosis... -
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- Randomized, crossover questionnaire survey of acceptabilities of controlled-release mesalazine tablets and granules in ulcerative colitis patients
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Yagisawa K, Kobayashi , Ozaki R, Okabayashi S, Toyonaga T, Miura M, Hayashida , Saito E, Nakano M, Matsubara , Hisamatsu , Hibi T
- KMID: 2438447
- Intest Res.
- 2019 Jan;17(1):87-93.
- doi: 10.5217/ir.2018.00078
BACKGROUND/AIMS: Oral mesalazine is an important treatment for ulcerative colitis (UC), and non-adherence to mesalazine increases the risk of relapse. Controlled-release (CR) mesalazine has 2 formulations: tablets and granules. The... -
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- Posaconazole for Prophylaxis of Fungal Infection in Pediatric Patients with Acute Myeloid Leukemia undergoing Induction Chemotherapy
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Kim SM, Ree YS, Kim JS, Kim SH, Son ES, Lyu CJ
- KMID: 2438543
- Korean J Clin Pharm.
- 2018 Sep;28(3):181-187.
- doi: 10.24304/kjcp.2018.28.3.181
BACKGROUND: Posaconazole is a broad-spectrum triazole antifungal agent and the most recommended prophylactic antifungal agent for patients with acute myeloid leukemia (AML) undergoing induction chemotherapy. In this study, we evaluated... -
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- Maternal Depression and Children's Screen Overuse
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Park S, Chang HY, Park EJ, Yoo H, Jo W, Kim SJ, Shin Y
- KMID: 2418616
- J Korean Med Sci.
- 2018 Aug;33(34):e219.
- doi: 10.3346/jkms.2018.33.e219
BACKGROUND: It is known that there are various factors associated with children's screen overuse. The aim of this study was to examine the effect of maternal depression on 2–5-year-old children's... -
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- The Beneficial Effect of Korean Red Ginseng Extract on Atopic Dermatitis Patients: An 8 Weeks Open, Noncomparative Clinical Study
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Kim H, Park CW, Cho SH
- KMID: 2419171
- Ann Dermatol.
- 2018 Jun;30(3):304-308.
- doi: 10.5021/ad.2018.30.3.304
BACKGROUND: Atopic dermatitis (AD) is a chronic or chronically relapsing, eczematous, severely pruritic inflammatory skin disorder. Korean red ginseng (KRG) has been shown previously to exhibit diverse biological effects including... -
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- Effect of preoperative pregabalin on postoperative pain after gastrectomy
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Park CY, Park SH, Lim DG, Choi EK
- KMID: 2415732
- Yeungnam Univ J Med.
- 2018 Jun;35(1):40-44.
- doi: 10.12701/yujm.2018.35.1.40
BACKGROUND: Pregabalin has been studied as a single or multimodal analgesic drug for postoperative pain management in different types of surgeries. We evaluated the analgesic effect of 150 mg of... -
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- Initial titration with 200 μg fentanyl buccal tablets: a retrospective safety analysis in Korean cancer patients
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Kwon MY, Cho HN, Koo DH, Lee YG, Oh S, Lee SS
- KMID: 2411586
- Korean J Intern Med.
- 2018 May;33(3):577-584.
- doi: 10.3904/kjim.2016.044
BACKGROUND/AIMS: Managing breakthrough pain (BTP) is important for many cancer patients because of the rapid onset and unpredictable nature of the pain episodes. Fentanyl buccal tablets (FBTs) are a rapid-onset... -
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- Pharmacokinetics of fixed-dose combination of rosuvastatin 20 mg and ezetimibe 10 mg compared to concurrent administration of individual tablets in healthy Korean subjects
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Hwang I, Park SI, Lee S, Lee B, Yu KS, Jeon JY, Kim MG
- KMID: 2420303
- Transl Clin Pharmacol.
- 2018 Mar;26(1):16-24.
- doi: 10.12793/tcp.2018.26.1.16
This study aimed to compare the pharmacokinetics of fixed-dose combination (FDC) tablet of rosuvastatin 20 mg/ezetimibe 10 mg with that of concurrent administration of individual rosuvastatin 20 mg tablet and... -
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- Albendazole and Praziquantel: Review and Safety Monitoring in Korea
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Hong ST
- KMID: 2407962
- Infect Chemother.
- 2018 Mar;50(1):1-10.
- doi: 10.3947/ic.2018.50.1.1
Albendazole (ADZ) and praziquantel (PZQT) have been used as anthelmintics for over 30 years. Worldwide, hundreds of millions tablets are administered to people and livestock every year. ADZ is poorly... -
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- A Case of a Visual Field Defect with Optical Coherence Tomography Changes after Sildenafil Citrate Overdose
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Park HS, Yang JY, Lee J
- KMID: 2406965
- J Korean Ophthalmol Soc.
- 2018 Mar;59(3):288-294.
- doi: 10.3341/jkos.2018.59.3.288
PURPOSE: A case of a transient visual field defect and a change in spectral-domain optical coherence tomography (SD-OCT) after an overdose of sildenafil citrate is described. CASE SUMMARY: A 67-year-old male... -
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- Pharmacokinetic Equivalence of the High Dose Strength Fixed-Dose Combination Tablet of Gemigliptin/Metformin Sustained Release (SR) and Individual Component Gemigliptin and Metformin XR Tablets in Healthy Subjects
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Cho YS, Lee SH, Lim HS, Bae KS
- KMID: 2421399
- J Korean Med Sci.
- 2018 Oct;33(41):e258.
- doi: 10.3346/jkms.2018.33.e258
BACKGROUND: In type 2 diabetes mellitus therapy, fixed-dose combination (FDC) can offer not only benefits in glucose control via the combined use of agents, but also increase patient compliance. The... -
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- Mortality from aluminum phosphide poisoning in Kermanshah Province, Iran: characteristics and predictive factors
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Navabi SM, Navabi J, Aghaei A, Shaahmadi , Heydari R
- KMID: 2438477
- Epidemiol Health.
- 2018;40:e2018022.
- doi: 10.4178/epih.e2018022
OBJECTIVES: Aluminum phosphide (ALP), also known in Iran as rice tablets, is one of the most effective rodenticides used to protect stored grain. However, ALP poisoning regularly causes mortality in... -
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