J Clin Pathol Qual Control.  1998 Jun;20(1):125-136.

Annual Report on External Quality Assessment in Therapeutic Drug Monitoring in Korea (1997)

• Kim JQ
• Kwon OH
• Kwon HJ
• Kim YK
• Kim JW
• Kim TJ
• Park IJ
• Song J
• Jung YS

Abstract

Two Trials of external quality assessment for therapeutic drug monitoring (TDM) were performed in 1997. A total of two specimens covering 26 test items were distributed. One specimen was distributed to 72 laboratories with 65 responses (90.3%) in the first trial and the other specimen to 75 laboratories with 66 responses (88.0%) in the second trial. Total twenty six test times including acetaminophen, amikacin, amitriptyline, carbamazepine, chloramphenicol, cyclosporine, digoxin, disopyramide, ethosuximide, free phenytoin, gentamicin, lidocaine, lithium, methotrexate, N-acetyl-procainamide, phenobarbital, phenytoin, primidone, procainamide, propranolol, quinidine, salicylate, theophylline, tobramycin, valproic acid, and vancomycin were evaluated. The results of two trials in 1997 were summarized as follows. 1. The percentage of laboratories able to perform TDM was less than 20% among all the members in the Korean Association of Quality Assurance for Clinical Pathology. 2. The most widely used TDM analyzer was Abbott TDx system but the kinds of analyzers became to be various. 3. The average number of test items per laboratory was around seven and the most common items were digoxin, phenytoin, phenobarbital, carbamazepine, theophylline and valproic acid.

MeSH Terms

Acetaminophen
Amikacin
Amitriptyline
Carbamazepine
Chloramphenicol
Cyclosporine
Digoxin
Disopyramide
Drug Monitoring*
Ethosuximide
Gentamicins
Korea*
Laboratories
Lidocaine
Lithium
Methotrexate
Pathology, Clinical
Phenobarbital
Phenytoin
Primidone
Procainamide
Propranolol
Quinidine
Theophylline
Tobramycin
Valproic Acid
Vancomycin
Acetaminophen
Amikacin
Amitriptyline
Carbamazepine
Chloramphenicol
Cyclosporine
Digoxin
Disopyramide
Ethosuximide
Gentamicins
Lidocaine
Lithium
Methotrexate
Phenobarbital
Phenytoin
Primidone
Procainamide
Propranolol
Quinidine
Theophylline
Tobramycin
Valproic Acid
Vancomycin