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Justicidin A Reduces β-Amyloid via Inhibiting Endocytosis of β-Amyloid Precursor Protein

Chun YS, Kwon OH, Oh HG, Cho YY, Yang HO, Chung S

β-amyloid precursor protein (APP) can be cleaved by α-, and γ-secretase at plasma membrane producing soluble ectodomain fragment (sAPPα). Alternatively, following endocytosis, APP is cleaved by β-, and γ-secretase at...
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Restoration of the Spinous Process Following Muscle-Preserving Posterior Lumbar Decompression via Sagittal Splitting of the Spinous Process

Wi SM, Lee HJ, Chang SY, Kwon OH, Lee CK, Chang BS, Kim H

BACKGROUND: In lumbar spinal stenosis, spinous process-splitting decompression has demonstrated good clinical outcomes with preservation of the posterior ligamentous complex and paraspinal muscles in comparison to conventional laminectomy, but the...
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Growth Behavior of Endothelial Cells According to Electrospun poly(D,L-Lactic-Co-Glycolic Acid) Fiber Diameter as a Tissue Engineering Scaffold

Ko YG, Park JH, Lee JB, Oh HH, Park WH, Cho D, Kwon OH

Investigating the effect of electrospun fiber diameter on endothelial cell proliferation provides an important guidance for the design of a fabric scaffold. In this study, we prepared biodegradable poly(D,L-lactic-co-glycolic acid)...
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Uremic Pericarditis Accompanying Cardiac Tamponade after Emergency Hemodialysis

Park HY, Kang SS, Kim YR, Kwon OH, Jin KB, Han SY, Park SB, Park WY

Although the incidence of uremic pericarditis was high in the past, it has decreased in recent decades with early and appropriate dialysis. However, cardiac tamponade caused by uremic pericarditis is...
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Hepatic Actinomycosis Mimicking a Malignant Tumor: Three Case Reports

Kwon OH, Kim JW

Various forms of hepatic actinomycosis can be observed on the imaging studies. We report here the imaging findings of three cases of hepatic actinomycosis, which presented as a solid mass...
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Our Experiences in Nipple Reconstruction Using the Hammond flap

Yang JD, Ryu JY, Ryu DW, Kwon OH, Bae SG, Lee JW, Choi KY, Chung HY, Cho BC

BACKGROUND: Nipple reconstruction following breast mound reconstruction is the final step in breast reconstruction. Although nipple reconstruction is a simple surgery, the psychological aspects of nipple reconstruction are thought to...
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Double Left Brachiocephalic Veins with Persistent Left Superior Vena Cava: A Case Report

Kwon OH, Lim JK, Lee JK, Hwang MS

Anomalous left brachiocephalic vein (ALBCV) is a rare condition of the major thoracic veins. It is usually associated with a congenital cardiac anomaly. Most reports on ALBCV are on aberrant...
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Valuable mobile applications for medical practice

Kwon OH

While the invention of computers has caused the rapid development of technology and civilization, the marriage of computers with mobile technology has continued to greatly change our daily lives in...
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Intra-Articular Nodular Fasciitis of the Knee: A Case Report of MRI Findings

Kwon OH, Cho KH, Suh JH, Choi JH

Nodular fasciitis, a benign soft tissue tumor consisting of myofibroblastic proliferation, is commonly located in the subcutaneous or inter- or intra-muscular layer of extremites. Intra-articular nodular fasciitis is extremely rare....
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Platelet-Rich Plasma: Quantitative Assessment of Growth Factor Levels and Comparative Analysis of Activated and Inactivated Groups

Lee JW, Kwon OH, Kim TK, Cho YK, Choi KY, Chung HY, Cho BC, Yang JD, Shin JH

BACKGROUND: Platelet-rich plasma (PRP) has more concentrated platelets than normal plasma (approximately 150-400x10(3) cell/dL). Platelets excrete several growth factors and cytokines that are associated with the healing and regeneration process....
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A known expressed sequence tag, BM742401, is a potent lincRNA inhibiting cancer metastasis

Park SM, Park SJ, Kim HJ, Kwon OH, Kang TW, Sohn HA, Kim SK, Moo Noh S, Song KS, Jang SJ, Sung Kim Y, Kim SY

  • KMID: 2154250
  • Exp Mol Med.
  • 2013 Jul;45(7):e31.
Long intergenic non-coding RNAs (lincRNAs) have historically been ignored in cancer biology. However, thousands of lincRNAs have been identified in mammals using recently developed genomic tools, including microarray and high-throughput...
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Peformance Evaluation of Bioporto Diagnostics' Neutrophil Gelatinase-associated Lipocalin Assay on Automated Clinical Chemistry Analyzer Hitachi 7600

Seo Y, Lee W, Kwon OH

  • KMID: 2200512
  • J Lab Med Qual Assur.
  • 2013 Jun;35(1):23-28.
BACKGROUND: Neutrophil gelatinase-associated lipocalin (NGAL) is known to be one of the ideal biomarkers for acute kidney injury providing early information on damage to the kidney. METHODS: We evaluated the performance...
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Evaluation of ACCU-CHEK(R) Inform II Blood Glucose Meter and ACCU-CHEK(R) Performa Strip

Seo Y, Won Y, Kim HS, Kwon OH, Lee W

  • KMID: 1820216
  • J Lab Med Qual Assur.
  • 2012 Jun;34(1):9-12.
BACKGROUND: Self-monitoring of blood glucose levels is recommended for all diabetic patients who receive insulin treatment, because such monitoring of glucose levels may aid in achieving better control in type...
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Evaluation of internal adaptation of dental adhesive restorations using micro-CT

Kwon OH, Park SH

OBJECTIVES: The internal adaptation of composite restorations with or without resin modified glass ionomer cement (RMGIC) was analyzed non-destructively using Microcomputed tomography (micro-CT). MATERIALS AND METHODS: Thirty intact human teeth were...
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Evaluation of the i-Smart 30 Point-of-Care Analyzer for Use in Clinical Laboratory Settings

Seok Y, Lee W, Yoon S, Won Y, Kwon OH

  • KMID: 1848729
  • J Lab Med Qual Assur.
  • 2011 Jun;33(1):25-30.
BACKGROUND: The i-Smart 30 point-of-care (POC) analyzer (i-SENS, Korea) is a compact and portable system used for the analysis of electrolytes (sodium, potassium, chloride) and hematocrit in whole blood samples....
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Annual Report on External Quality Assessment in Immunoassay in Korea (2009)

Kim HS, Kim YL, Park J, Kwon OH, Kim DA, Kim JQ, Sun YK, Shin S, Lim HS, Chun HS, Jung YS

  • KMID: 2200551
  • J Lab Med Qual Assur.
  • 2010 Jun;32(1):103-114.
Two trials with 15 test items of external quality assessment survey were performed in 2009. The test items were constituted three immunoassay categories, i.e., tumor markers, thyroid hormones and immunoproteins...
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Performance Characteristics of the UniCel DxI 800 Immunoassay for the Maternal Serum Quadruple Test, Including Median Values for Each Week of Gestation, in Korean Women

Lee JH, Park Y, Suh B, Song SM, Kwon OH, Kim JH

BACKGROUND: Maternal serum prenatal quadruple screening includes testing for alpha-fetoprotein (AFP), human chorionic gonadotrophin (hCG), unconjugated estriol (uE3), and dimeric inhibin A (DIA). We evaluated quadruple screening using an automated...
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Evaluation of HbA1c on COBAS INTEGRA 800 Closed Tube System Compared with Variant II Turbo

Lee E, Yoon S, Kim SH, Lee W, Kwon OH

  • KMID: 2200540
  • J Lab Med Qual Assur.
  • 2010 Dec;32(2):225-228.
BACKGROUND: We evaluated the HbA1c assay on COBAS INTEGRA 800 Closed Tube System (Roche Diagnostics, USA). METHODS: Precision was determined following Clinical and Laboratory Standards Institute (CLSI) EP5-A2 using the Lyphochek...
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Annual Report on External Quality Assessment of Immunoassay Subcommittee in Korean Clinical Laboratory Survey (2008)

Kim HS, Kim YL, Park J, Kwon OH, Kim DA, Kim JQ, Sun YK, Shin S, Lim HS, Chun HS, Jung YS

  • KMID: 2200579
  • J Lab Med Qual Assur.
  • 2009 Jun;31(1):105-124.
Two trials of external quality assessment were performed in 2008. The first and the second trials assessed by three test categories, i.e., tumor markers, thyroid hormones and immunoproteins (IgG, IgM,...
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Differences in Hemoglobin Levels as Measured by Blood Gas and Auto Blood Cell Count Analyzers

Yoon S, Cha Y, Kwon OH, Lee W

  • KMID: 2300052
  • Korean J Blood Transfus.
  • 2009 Dec;20(3):242-246.
BACKGROUND: While point-of-care testing is being used increasingly as a basis for making decisions about erythrocyte transfusion, no valid standards or guidelines have been developed concerning the accuracy of measuring...
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