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Malignant melanoma of the gallbladder: A case report and literature review

Jeon HJ, Kwon HJ, Kim SG, Hwang YJ

Metastatic melanoma of the gallbladder is extremely rare. It has a poor prognosis. Its optimal treatment remains unclear. Surgical resection is generally considered the mainstay of treatment. However, there are...
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Cherry Hemangioma Treated Using the Pharaon Lipo Laser: A Report of Two Cases

Kwon HJ, Kim JH, Yoon JH, Bang JH, Kim KH

  • KMID: 2518992
  • Korean J Dermatol.
  • 2021 Jul;59(6):477-482.
A cherry hemangioma is a type of capillary hemangioma that commonly occurs in older adults. Despite its benign nature, treatment is often required for cosmetically unacceptable lesions, and therapeutic options...
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Thymoma-Associated Paraneoplastic Myositis, Presenting with Rapidly Progressive Muscle Contractures

Kim JH, Jang H, Kwon HJ, Suh YL, Min JH

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Dexamethasone reduces infectious bursal disease mortality in chickens

Shin SY, Han TH, Kwon HJ, Kim SJ, Ryu PD

Very virulent infectious bursal disease virus (vvIBDV) causes high mortality in chickens but measures to reduce the mortality have not been explored. Chickens (8–9 weeks) were treated with 3 agents...
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Differential Signaling and Virus Production in Calu-3 Cells and Vero Cells upon SARS-CoV-2 Infection

Park BK, Kim D, Park S, Maharjan S, Kim J, Choi JK, Akauliya M, Lee Y, Kwon HJ

Severe acute respiratory syndrome CoV-2 (SARS-CoV-2) is responsible for the current coronavirus disease 2019 (COVID-19) pandemic. Signaling pathways that are essential for virus production have potential as therapeutic targets against...
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Protective Role of Transduced Tat-Thioredoxin1 (Trx1) against Oxidative Stress-Induced Neuronal Cell Death via ASK1-MAPK Signal Pathway

Yeo EJ, Eum WS, Yeo HJ, Choi YJ, Sohn EJ, Kwon HJ, Kim DW, Kim DS, Cho SW, Park J, Han KH, Lee KW, Park JK, Shin MJ, Choi SY

Oxidative stress plays a crucial role in the development of neuronal disorders including brain ischemic injury. Thioredoxin 1 (Trx1), a 12 kDa oxidoreductase, has anti-oxidant and anti-apoptotic functions in various...
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Discovery of New Fusion Inhibitor Peptides against SARS-CoV-2 by Targeting the Spike S2 Subunit

Kandeel M, Yamamoto M, Tani H, Kobayashi A, Gohda J, Kawaguchi Y, Park BK, Kwon HJ, Inoue Ji, Alkattan A

A novel coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), caused a worldwide pandemic. Our aim in this study is to produce new fusion inhibitors against SARS-CoV-2, which can be the...
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BF-7 Improved Memory Function and Protected Neuron from Oxidative Stress

Lee M, Lee S, Lee J, Min K, Lee K, Yeo J, Kwon H, Lee J, Kang Y, Lee D, Chung Y, Kim K, Kim S, Lee W

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Effect of Pressure Based Customized 3-Dimensional Printing Insole in Pediatric Flexible Flat Foot Patients

Lee SW, Choi JH, Kwon HJ, Song KS

Purpose: A flatfoot that fails to form a longitudinal foot arch is a common lower limb deformity in children. This study evaluated the structural and functional effects of the insole...
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Quisqualis indica extract ameliorates low urinary tract symptoms in testosterone propionate-induced benign prostatic hyperplasia rats

Kim Dg, Kim Jh, Kwon HJ, Lim JH, Lee KP

Benign prostate hyperplasia (BPH) is a common disease in old-age males, accounting for approximately 77% of morbidity within the age range of 40 to 70 years. It has been shown that...
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Changes of fat-mass and obesity-associated protein expression in the hippocampus in animal models of high-fat diet-induced obesity and D-galactose-induced aging

Kang MS, Kim TH, Choi JH, Kim W, Jung HY, Hwang IK, Kim W, Kwon HJ, Kim DW

Fat-mass and obesity-associated protein (Fto) is highly expressed in the brain including, the hippocampus, and its expression is significantly decreased in the brain of Alzheimer’s disease patients. In the present...
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Epidemiological Characteristics of COVID-19 Outbreak at Fitness Centers in Cheonan, Korea

Bae S, Kim H, Jung TY, Lim JA, Jo DH, Kang GS, Jeong SH, Choi DK, Kim HJ, Cheon YH, Chun Mk, Kim M, Choi S, Chun C, Shin SH, Kim HK, Park YJ, Park O, Kwon HJ

Background: In February 2020, a coronavirus disease 2019 (COVID-19) outbreak was reported in fitness centers in Cheonan, Korea. Methods: From February 24 to March 13, an epidemiological investigation was conducted on...
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Unilateral Diaphragm Paralysis Associated With Neurosyphilis: A Case Report

Huh S, Chung JH, Kwon HJ, Ko HY

Diaphragm dysfunction can originate from various etiologies, and bilaterality of the dysfunction depends on the cause. Symptoms of diaphragm dysfunction vary depending on the degree of phrenic nerve denervation, spinal...
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Association of Sleep Duration with Hand Grip Strength in Adults: Korea National Health and Nutrition Examination Survey (2014–2017)

Kim WJ, Choi JK, Kwon HJ, Shin JY, Oh EJ, Kim KJ

Background: Hand grip strength (HGS) is used clinically with regards to rehabilitation and recommended as a basic measure in determiningmusculoskeletal function, weakness, and disability. The purpose of this study was...
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Ischemic Colitis due to Fibromuscular Dysplasia Limited to the Inferior Mesenteric Artery: A Case Report

Park JH, Kwon HJ, Chang KS, Kang KA, Kim MS

Fibromuscular dysplasia is a nonatheromatous, noninflammatory arterial disorder that results in stenosis and/or aneurysm formation and rarely involves the mesenteric arteries. Herein, we report a case of fibromuscular dysplasia limited...
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Small Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Fusion by Targeting Cavities on Heptad Repeat Trimers

Kandeel M, Yamamoto M, Al-Taher A, Watanabe A, Oh-hashi K, Park BK, Kwon HJ, Inoue Ji, Al-Nazawi M

Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a newly emerging viral disease with fatal outcomes. However, no MERS-CoV-specific treatment is commercially available. Given the absence of previous structure-based drug discovery...
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Gastric cancer and adenomatous colorectal polyp concomitant with pyogenic liver abscess and bacteremia

Kang MK, Kwon HJ, Kim MC

Synchronous gastric cancer and adenomatous colorectal polyp in patients with Klebsiella pneumoniae-induced pyogenic liver abscess (KP-PLA) and bacteremia is a rare presentation. A 58-year-old man with a 6-month history of...
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Anti-microbial and anti-inflammatory effects of Cheonwangbosim-dan against Helicobacter pylori-induced gastritis

Park HS, Jeong HY, Kim YS, Seo CS, Ha H, Kwon HJ

Background: There are various Helicobacter species colonizing the stomachs of animals. Although Helicobacter species usually cause asymptomatic infection in the hosts, clinical signs can occur due to gastritis associated with...
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Associations between Exposure to Bisphenol A and Behavioral and Cognitive Function in Children with Attention-deficit/Hyperactivity Disorder: A Case-control Study

Yoo SJ, Joo H, Kim D, Lim MH, Kim E, Ha M, Kwon HJ, Paik KC, Kim KM

Objective: Bisphenol A (BPA) is a widely produced synthetic chemical used to manufacture polycarbonate plastics and epoxy resins. We aimed to investigate the association between exposure to BPA and behavioral...
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Mosapride Improves Lower Esophageal Sphincter and Esophageal Body Function in Patients With Minor Disorders of Esophageal Peristalsis

Kim SE, Park MI, Park SJ, Moon W, Kim JH, Jung K, Kwon HJ, Kim GM, Joo HK

  • KMID: 2500680
  • J Neurogastroenterol Motil.
  • 2020 Apr;26(2):232-240.
  • doi: 10.5056/jnm19062
Background/Aims High-resolution manometry (HRM) has broadened the awareness of minor esophageal peristaltic disorders. However, the treatments for these minor disorders are limited and the role of prokinetics has been controversial....
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