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History and Future of Treatment for Acute Stage Kawasaki Disease

Ishii M, Ebato T, Kato H

Kawasaki disease is a form of vasculitis, mainly in small and medium arteries of unknown origin, occurring frequently in childhood. It is the leading form of childhood-onset acquired heart disease...
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Characteristics and Management of Cyclosporine-associated Adverse Gastrointestinal Events

Koh WS, Ko YW, Kim JE, Ko JY, Ro YS

  • KMID: 2470214
  • Korean J Dermatol.
  • 2019 Dec;57(10):608-616.
BACKGROUND: Cyclosporine (CS) is widely used to treat various skin diseases. Gastrointestinal (GI) discomfort is the most common adverse effect of orally administered CS for dermatologic indications. However, few studies...
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Cross-sectional analysis of immunosuppressive regimens focused on everolimus after liver transplantation in a Korean high-volume transplantation center

Kang SH, Hwang S, Ha TY, Song GW, Jung DH, Ahn CS, Moon DB, Kim KH, Park GC, Yoon YI, Park YH, Cho HD, Kwon JH, Chung YK, Choi JU, Lee SG

BACKGROUND: The mammalian target of the rapamycin inhibitor has dual inhibitory effects on cell growth and angiogenesis. This study aimed to analyze the usage of everolimus on actual immunosuppression (IS)...
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The Effect of Topical 10% N-acetylcysteine on Refractory Filamentary Keratitis

Lim HR, Koh JW

PURPOSE: To analyze the effects of topical 10% N-acetylcysteine on patients with refractory filamentary keratitis. METHODS: The present study included 29 eyes from 20 patients diagnosed with filamentary keratitis. We analyzed...
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The Effects of Systemic Psoriasis Therapies on the C-Reactive Protein and the Neutrophil-Lymphocyte Ratio

Aktaş Karabay E, Aksu Çerman A, Demir D, Kıvanç Altunay I

BACKGROUND: Currently, no generally accepted laboratory marker for monitorizing the disease activity and therapy response of psoriasis is known. OBJECTIVE: The aim of the study is to evaluate the effects of...
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Comparative Study of Quality of Life in Patients with Scalp Psoriasis Treated Using Topical Steroid Alone vs. Topical Steroid Combined with Cyclosporine

Kim M, Yang S, Kim BR, Youn SW

  • KMID: 2465915
  • Korean J Dermatol.
  • 2019 Nov;57(9):513-518.
BACKGROUND: Scalp psoriasis severely affects patients' quality of life, and patients may occasionally be refractory to topical steroid application. Although systemic therapy combined with topical steroid application is recommended for...
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A Case of Henoch-Schönlein Purpura with Fulminant Complications and Its Long-term Outcome

Lee DH, LEE ES, Hong J, Park KH, Pai KS

Henoch-Schönlein purpura (HSP) is a systemic vasculitis characterized by purpura, arthritis, abdominal pain, and nephritis. Gastrointestinal involvement can manifest as pain, intussusception, intestinal bleeding, and intestinal perforation. We report a...
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A Boy with Chronic Active EBV Infection Presented as Mosquito Bite Hypersensitivity Progressed to Fatal Hemophagocytic Lymphohistiocytosis due to NK Cell Neoplasm

Lee JA, Han SB, Chung NG, Kang JH, Kim M, Jeong DC

Chronic active Epstein-Barr virus (CAEBV) infection is characterized by recurrent infectious mononucleosis (IM)-like symptoms and an unusual pattern of anti-EBV antibodies. We report a boy with CAEBV who progressed to...
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Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases: Part 3. Idiopathic Nonspecific Interstitial Pneumonia

Lee J, Kim YH, Kang JY, Jegal Y, Park SY, on behalf of Korean Interstitial Lung Diseases Study Group

Idiopathic nonspecific interstitial pneumonia (NSIP) is one of the varieties of idiopathic interstitial pneumonias. Diagnosis of idiopathic NSIP can be done via multidisciplinary approach in which the clinical, radiologic, and...
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Cyclosporin A aggravates hydrogen peroxide-induced cell death in kidney proximal tubule epithelial cells

Moon D, Kim J

Cyclosporin A (CsA) does not only exert a toxic effect on kidney parenchymal cells, but also protects them against necrotic cell death by inhibiting opening of mitochondrial permeability transition pore....
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Fine dust and eye health

Choi SY, Eom Y, Song JS, Kim HM

This paper aims to make recommendations for the management of eye health related to fine dust exposure. Fine dust is one of the biggest problems related to air pollution in...
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Effectiveness of Cyclosporine-steroid Treatment after Cataract Surgery according to Dry Eye Severity

Park JY, Yang SC, Park YM, Lee JE, Park CY, Lee JS

PURPOSE: To evaluate the effectiveness of topically administered 0.05% cyclosporine combined with a topical steroid in the early postoperative period after cataract surgery, and to compare the therapeutic efficacy according...
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Development of a physiologically-based pharmacokinetic model for cyclosporine in Asian children with renal impairment

Yoon S, Yi S, Rhee SJ, Lee HA, Kim Y, Yu KS, Chung JY

This study aimed to assess the pharmacokinetics of cyclosporine A (CsA) in Asian children with renal impairment (RI) by developing a physiologically-based pharmacokinetic (PBPK) model with Simcyp Simulator. The PBPK...
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Clinical outcomes and effects of treatment in older patients with idiopathic membranous nephropathy

Kim Y, Yoon HE, Chung BH, Choi BS, Park CW, Yang CW, Kim YS, Hong YA, Kim SY, Chang YK, Hwang HS

BACKGROUND/AIMS: Membranous nephropathy (MN) is the most common primary glomerular disease diagnosed in older patients. Few reports describe the clinical outcomes in older patients with idiopathic MN. METHODS: The outcomes of...
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Factors Predicting the Response to Cyclosporin Treatment in Patients With Chronic Spontaneous Urticaria: A Systematic Review

Kulthanan , Subchookul C, Hunnangkul S, Chularojanamontri L, Tuchinda P

PURPOSE: This study aimed to systemically review literature relating to factors that could potentially predict a favorable response to cyclosporine A (CsA) treatment for chronic spontaneous urticaria (CSU). METHODS: A systematic...
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Pustulotic Arthro-osteitis Improved with Anti TNF-α Inhibitor

Park HS, Kim JH, Kim HW, Kim SC

  • KMID: 2457688
  • Korean J Dermatol.
  • 2019 Aug;57(7):378-382.
Pustulotic arthro-osteitis (PAO) is a rare chronic inflammatory disorder characterized by inflammatory osteitis of the sternoclavicular joint and palmoplantar pustulosis. Here, we report a case of PAO that was successfully...
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The Korean Organ Transplant Registry (KOTRY): Second Official Adult Heart Transplant Report

Kim D, Choi JO, Oh J, Cho HJ, Jung SH, Lee HY, Kang SM, Kim JJ, Jeon ES

BACKGROUND AND OBJECTIVES: This second adult heart transplantation (HTx) report is based on Korean Organ Transplant Registry data submitted on 400 HTxs in recipients of all ages. METHODS: From March 2014...
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Efficacy of Topical Cyclosporine Nanoemulsion 0.05% Compared with Topical Cyclosporine Emulsion 0.05% and Diquafosol 3% in Dry Eye

Park CH, Kim MK, Kim EC, Kim JY, Kim TI, Kim HK, Song JS, Yoon KC, Lee DH, Lee HK, Chung TY, Choi CY, Kim HS

PURPOSE: To evaluate the efficacy and safety of cyclosporine nanoemulsion 0.05% compared to cyclosporine emulsion 0.05% and diquafosol sodium 3%. METHODS: This was a multicenter, randomized, evaluator-masked, active control, parallel, phase...
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Comparative Study of Clinical Characteristics according to Therapeutic Efficacy and Drug Survival of Cyclosporine or Methotrexate in Psoriasis Vulgaris

Lee HS, Kwon SH, Lee ES

No abstract available.
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Cold Urticaria: Clinical Features and Natural Course in a Tropical Country

Kulthanan , Tuchinda P, Chularojanamontri L, Kiratiwongwan R

PURPOSE: To review the clinical features and natural courses of cold urticaria (ColdU) in a tropical country. METHODS: A retrospective chart review was performed of patients who visited Siriraj Urticaria Clinic,...
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